8-(4-sulfophenyl)theophylline has been researched along with 8-phenyltheophylline in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Daly, JW; Padgett, WL; Shamim, MT; Ukena, D | 1 |
| Butts-Lamb, P; Daly, JW; Padgett, W; Shamim, MT; Waters, J | 1 |
| Badger, EW; Bristol, JA; Bruns, RF; Haleen, SJ; Hamilton, HW; Ortwine, DF; Steffen, RP; Worth, DF | 1 |
| Bristol, JA; Hamilton, HW; Ortwine, DF; Worth, DF | 1 |
| Daly, JW; Gallo-Rodriguez, C; Jacobson, KA; Kiriasis, L; Manning, M; Müller, C; Neumeyer, JL; Pfleiderer, W; Shi, D | 1 |
| Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE | 1 |
| Müller, CE; Yan, L | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Birch, BD; Gaba, DM; Louie, GL; Maze, M; Vickery, RG | 1 |
| Geiger, JD; Westerberg, VS | 1 |
| Macgregor, DG; Stone, TW | 1 |
| Coney, AM; Marshall, JM | 1 |
| Feigl, EO; Gorman, MW; Olsson, RA; Richmond, KN; Tune, JD | 1 |
| Goshgarian, HG; Nantwi, KD | 1 |
1 review(s) available for 8-(4-sulfophenyl)theophylline and 8-phenyltheophylline
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
15 other study(ies) available for 8-(4-sulfophenyl)theophylline and 8-phenyltheophylline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions.
Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Brain; Caffeine; Chemical Phenomena; Chemistry; Humans; Molecular Structure; Phenylisopropyladenosine; Pheochromocytoma; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Tumor Cells, Cultured; Xanthines | 1989 |
1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors.
Topics: Adenosine; Animals; Cerebral Cortex; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Solubility; Structure-Activity Relationship | 1985 |
Synthesis of xanthines as adenosine antagonists, a practical quantitative structure-activity relationship application.
Topics: Adenosine; Animals; Brain; Cattle; Heart; In Vitro Techniques; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1985 |
Synthesis and structure-activity relationships of pyrazolo[4,3-d]pyrimidin-7-ones as adenosine receptor antagonists.
Topics: Adenosine; Animals; Binding, Competitive; Brain; Cattle; Cell Membrane; Indicators and Reagents; Magnetic Resonance Spectroscopy; Pyrazoles; Pyrimidinones; Receptors, Purinergic; Spectrophotometry, Infrared; Structure-Activity Relationship | 1987 |
Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.
Topics: Acylation; Alkylation; Animals; Brain; Caffeine; Cell Membrane; Cyclization; Molecular Structure; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Trifluoroacetic Acid; Xanthines | 1993 |
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines | 2002 |
Preparation, properties, reactions, and adenosine receptor affinities of sulfophenylxanthine nitrophenyl esters: toward the development of sulfonic acid prodrugs with peroral bioavailability.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Administration, Oral; Animals; Biological Availability; Brain; Cattle; Cell Line; Cricetinae; Drug Stability; Esters; Humans; Hydrolysis; In Vitro Techniques; Liver; Nitrobenzenes; Prodrugs; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Sulfonic Acids; Xanthines | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
L-phenylisopropyladenosine (L-PIA) diminishes halothane anesthetic requirements and decreases noradrenergic neurotransmission in rats.
Topics: Adenosine; Anesthesia; Animals; Brain; Halothane; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1988 |
Central effects of adenosine analogs on stress-induced gastric ulcer formation.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Injections, Intraventricular; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Stomach Ulcer; Stress, Physiological; Theophylline | 1987 |
Blockade by 1,3-dipropyl-8-cyclopentylxanthine (CPX) of purine protection against kainate neurotoxicity.
Topics: Animals; Kainic Acid; Male; Nerve Degeneration; Phenylisopropyladenosine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation | 1998 |
Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Endothelin; Tetrazoles; Theophylline | 2000 |
Alkylxanthine-induced recovery of respiratory function following cervical spinal cord injury in adult rats.
Topics: Animals; Bronchodilator Agents; Cervical Vertebrae; Diaphragm; Dose-Response Relationship, Drug; Female; Functional Laterality; Phrenic Nerve; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Spinal Cord Injuries; Theophylline; Xanthines | 2001 |