Page last updated: 2024-09-03

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and caffeine

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine has been researched along with caffeine in 4 studies

Compound Research Comparison

Studies
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Trials
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Recent Studies (post-2010)
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Studies
(caffeine)
Trials
(caffeine)
Recent Studies (post-2010) (caffeine)
160325,5012,3936,825

Protein Interaction Comparison

ProteinTaxonomy8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine (IC50)caffeine (IC50)
AcetylcholinesteraseHomo sapiens (human)7.25

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; van Galen, PJ; Williams, M1
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE1
Dunwiddie, TV; Thümmler, S1

Reviews

1 review(s) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and caffeine

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

3 other study(ies) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and caffeine

ArticleYear
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines

1994
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

    Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines

2002
Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism.
    Journal of neurophysiology, 2000, Volume: 83, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Adrenergic Antagonists; Animals; Caffeine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Periodicity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Theophylline; Xanthines

2000