8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 3 studies

Compound Research Comparison

Studies (8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)	Trials (8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)	Recent Studies (post-2010) (8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)	Studies (adenosine-5'-(n-ethylcarboxamide))	Trials (adenosine-5'-(n-ethylcarboxamide))	Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide))
16	0	3	1,333	4	133

Protein Interaction Comparison

Protein	Taxonomy	adenosine-5'-(n-ethylcarboxamide) (IC50)
Adenosine receptor A3	Homo sapiens (human)	0.0097
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.4498
Adenosine receptor A2a	Homo sapiens (human)	0.0336
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	0.0175
Adenosine receptor A1	Homo sapiens (human)	0.0007
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	0.0513
Adenosine receptor A1	Gallus gallus (chicken)	0.017

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Craig, RH; Daluge, SM; Earl, CQ; Linden, J; Patel, A	1
Ahern, DG; Jacobson, KA; Ji, X; Kim, YC; Linden, J	1

Reviews

1 review(s) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992

Other Studies

2 other study(ies) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)

Article	Year
125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors. Journal of medicinal chemistry, 1988, Volume: 31, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Affinity Labels; Algorithms; Animals; Binding, Competitive; Brain; Cattle; Humans; Iodine Radioisotopes; Iodobenzenes; Isotope Labeling; Kinetics; Ligands; Membranes; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Chloride; Structure-Activity Relationship; Theophylline; Xanthines	1988
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors. Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6 Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium	2001

Article

Year

125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.

Journal of medicinal chemistry, 1988, Volume: 31, Issue:4

Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Affinity Labels; Algorithms; Animals; Binding, Competitive; Brain; Cattle; Humans; Iodine Radioisotopes; Iodobenzenes; Isotope Labeling; Kinetics; Ligands; Membranes; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Chloride; Structure-Activity Relationship; Theophylline; Xanthines

1988

[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.

Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium

2001