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8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine has been researched along with 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine in 7 studies

Compound Research Comparison

Studies
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Trials
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Recent Studies (post-2010)
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Studies
(8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine)
Trials
(8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine)
Recent Studies (post-2010) (8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine)
1603108014

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; van Galen, PJ; Williams, M1
Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S1
Daly, JW; Jacobson, KA; Kirk, KL; Padgett, WL1
Daly, JW; Jacobson, KA; Kirk, KL; Padgett, W; Ukena, D1
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL1
Jacobson, KA; Ji, X; Kim, YC; Linden, J; Melman, N1
Ahern, DG; Jacobson, KA; Ji, X; Kim, YC; Linden, J1

Reviews

1 review(s) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

6 other study(ies) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

ArticleYear
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines

1989
Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Adenosine; Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Esterification; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthenes; Xanthines

1985
Xanthine functionalized congeners as potent ligands at A2-adenosine receptors.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Adenylyl Cyclases; Blood Platelets; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1987
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.
    Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines

1994
Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors.
    Journal of medicinal chemistry, 2000, Mar-23, Volume: 43, Issue:6

    Topics: Anilides; Animals; Calcium; Cell Line; Humans; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship; Xanthines

2000
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium

2001