8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 8-(3-chlorostyryl)caffeine

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine has been researched along with 8-(3-chlorostyryl)caffeine in 2 studies

Compound Research Comparison

Studies (8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)	Trials (8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)	Recent Studies (post-2010) (8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)	Studies (8-(3-chlorostyryl)caffeine)	Trials (8-(3-chlorostyryl)caffeine)	Recent Studies (post-2010) (8-(3-chlorostyryl)caffeine)
16	0	3	101	0	22

Protein Interaction Comparison

Protein	Taxonomy	8-(3-chlorostyryl)caffeine (IC50)
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	0.0385
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.0385
Amine oxidase [flavin-containing] B	Homo sapiens (human)	0.1603

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL	1
Dunwiddie, TV; Thümmler, S	1

Other Studies

2 other study(ies) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 8-(3-chlorostyryl)caffeine

Article	Year
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines	1994
Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. Journal of neurophysiology, 2000, Volume: 83, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Adrenergic Antagonists; Animals; Caffeine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Periodicity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Theophylline; Xanthines	2000

Article

Year

Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.

Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20

Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines

1994

Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism.

Journal of neurophysiology, 2000, Volume: 83, Issue:4

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Adrenergic Antagonists; Animals; Caffeine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Periodicity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Theophylline; Xanthines

2000