Page last updated: 2024-09-03

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 2-amino-5-phosphonovalerate

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine has been researched along with 2-amino-5-phosphonovalerate in 1 studies

*2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. [MeSH]

*2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors. [MeSH]

Compound Research Comparison

Studies
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Trials
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Recent Studies (post-2010)
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Studies
(2-amino-5-phosphonovalerate)
Trials
(2-amino-5-phosphonovalerate)
Recent Studies (post-2010) (2-amino-5-phosphonovalerate)
16034,3931539

Protein Interaction Comparison

ProteinTaxonomy8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine (IC50)2-amino-5-phosphonovalerate (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.29
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.29

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dunwiddie, TV; Thümmler, S1

Other Studies

1 other study(ies) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 2-amino-5-phosphonovalerate

ArticleYear
Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism.
    Journal of neurophysiology, 2000, Volume: 83, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; Adrenergic Antagonists; Animals; Caffeine; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Male; N-Methylaspartate; Neuronal Plasticity; Neurons; Periodicity; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Theophylline; Xanthines

2000