Page last updated: 2024-09-03

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 1,3-diethyl-8-phenylxanthine

8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine has been researched along with 1,3-diethyl-8-phenylxanthine in 4 studies

Compound Research Comparison

Studies
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Trials
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Recent Studies (post-2010)
(8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine)
Studies
(1,3-diethyl-8-phenylxanthine)
Trials
(1,3-diethyl-8-phenylxanthine)
Recent Studies (post-2010) (1,3-diethyl-8-phenylxanthine)
16033601

Protein Interaction Comparison

ProteinTaxonomy8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine (IC50)1,3-diethyl-8-phenylxanthine (IC50)
Adenosine receptor A1Rattus norvegicus (Norway rat)0.04
Adenosine receptor A1Bos taurus (cattle)0.003

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S1
Craig, RH; Daluge, SM; Earl, CQ; Linden, J; Patel, A1
Daly, JW; Jacobson, KA; Kirk, KL; Padgett, W; Ukena, D1
Jacobson, KA; Kim, HS; Kim, SA; Linden, J; Marshall, MA; Melman, N; Müller, CE1

Other Studies

4 other study(ies) available for 8-(4-carboxymethyloxy)phenyl-1,3-dipropylxanthine and 1,3-diethyl-8-phenylxanthine

ArticleYear
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:8

    Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines

1989
125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Affinity Labels; Algorithms; Animals; Binding, Competitive; Brain; Cattle; Humans; Iodine Radioisotopes; Iodobenzenes; Isotope Labeling; Kinetics; Ligands; Membranes; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Chloride; Structure-Activity Relationship; Theophylline; Xanthines

1988
Xanthine functionalized congeners as potent ligands at A2-adenosine receptors.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Adenylyl Cyclases; Blood Platelets; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Receptors, Purinergic; Structure-Activity Relationship; Xanthines

1987
Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.
    Journal of medicinal chemistry, 2002, May-23, Volume: 45, Issue:11

    Topics: Animals; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Ligands; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship; Xanthines

2002