Compounds > 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine
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8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and zm 241385

8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine has been researched along with zm 241385 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T1
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW1
Ahern, DG; Jacobson, KA; Ji, X; Kim, YC; Linden, J1
Castelhano, AL; Ma, C; MacLennan, SJ; McKibben, B; Song, JP; Steinig, AG; Stewart, M1
Andrews, SP; Congreve, M; Errey, JC; Marshall, FH; Mason, JS; Robertson, N; Tehan, B; Weir, M; Zhukov, A1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L1
Capuano, B; Jörg, M; Mak, FS; Miller, ND; Scammells, PJ; Shonberg, J; Yuriev, E1
Handa, C; Momose, T; Muranaka, H; Ozawa, T1
Azuaje, J; Brea, JM; Carbajales, C; Contino, M; Crespo, A; Díaz-Holguín, A; Estévez, JC; García-Mera, X; Gioé-Gallo, C; Gutiérrez-de-Terán, H; Loza, MI; Majellaro, M; Prieto-Díaz, R; Rodríguez-García, C; Sotelo, E; Stefanachi, A; Val, C1
Bennett, K; Congreve, M; Doré, AS; Errey, JC; Hollenstein, K; Hurrell, E; Magnani, F; Marshall, FH; Ng, I; Robertson, N; Tate, CG; Tehan, B; Weir, M1

Reviews

1 review(s) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and zm 241385

ArticleYear
Fluorescent ligands for adenosine receptors.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2013

Other Studies

9 other study(ies) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and zm 241385

ArticleYear
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
    Molecular pharmacology, 1999, Volume: 56, Issue:4

    Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines

1999
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
    Molecular pharmacology, 2000, Volume: 58, Issue:6

    Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine

2000
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium

2001
[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors.
    Biochemical pharmacology, 2004, Jul-15, Volume: 68, Issue:2

    Topics: Adenosine A2 Receptor Antagonists; Cells, Cultured; Humans; Pyrimidines; Pyrroles; Radioligand Assay; Time Factors; Tritium

2004
Biophysical mapping of the adenosine A2A receptor.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Drug Design; Ligands; Models, Molecular; Mutation; Pyrimidines; Receptor, Adenosine A2A; Small Molecule Libraries; Triazines; Triazoles; Xanthines

2011
Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space.
    Bioorganic & medicinal chemistry letters, 2013, Jun-01, Volume: 23, Issue:11

    Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Humans; Hydrogen Bonding; Ligands; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Receptor, Adenosine A2A; Triazines; Triazoles

2013
Photoaffinity Labeling of the Human A
    ACS medicinal chemistry letters, 2017, Jun-08, Volume: 8, Issue:6

    Topics:

2017
Optimization of 2-Amino-4,6-diarylpyrimidine-5-carbonitriles as Potent and Selective A
    Journal of medicinal chemistry, 2022, 02-10, Volume: 65, Issue:3

    Topics: Adenosine A1 Receptor Antagonists; Binding Sites; Cell Line; Drug Design; Drug Stability; Humans; Kinetics; Molecular Docking Simulation; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Structure-Activity Relationship

2022
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine.
    Structure (London, England : 1993), 2011, Sep-07, Volume: 19, Issue:9

    Topics: Adenosine A2 Receptor Agonists; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Caffeine; Crystallography, X-Ray; HEK293 Cells; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Stability; Protein Structure, Tertiary; Receptor, Adenosine A2A; Surface Properties; Triazines; Triazoles; Xanthines

2011