Compounds > 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

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8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and theophylline

8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine has been researched along with theophylline in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (15.79)	18.7374
1990's	13 (68.42)	18.2507
2000's	1 (5.26)	29.6817
2010's	2 (10.53)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F	1
Ichikawa, S; Ishii, A; Nonaka, H; Shimada, J; Suzuki, F	1
Jacobson, KA; van Galen, PJ; Williams, M	1
Barone, S; Bradbury, BJ; Campagne, JM; Daly, JW; Jacobson, KA; Kammula, U; Kiriasis, L; Neumeyer, JL; Pfleiderer, W; Secunda, S	1
Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD	1
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL	1
Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andrews, SP; Congreve, M; Errey, JC; Marshall, FH; Mason, JS; Robertson, N; Tehan, B; Weir, M; Zhukov, A	1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L	1
Baumgold, J; Jacobson, KA; Nikodijevic, O	1
Jacobson, KA; Ji, XD; Stiles, GL	1
Gobran, LI; Griese, M; Rooney, SA	1
Bealer, SL; Proctor, KG; Stojanov, I	1
Daly, JW; Deckert, J; Jacobson, KA; Marangos, PJ; Morgan, PF	1
Churchill, PC; Jacobson, KA; Leahy, AE; Rossi, NF	1
el-Sawalhi, MM; Ismail, NA; Megahed, YM; Shaheen, AA	1
Richardt, G; Schreieck, J	1

Reviews

2 review(s) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and theophylline

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Fluorescent ligands for adenosine receptors. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	2013

Other Studies

17 other study(ies) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and theophylline

Article	Year
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure. Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16 Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines	1992
(E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists. Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Corpus Striatum; Guinea Pigs; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Structure-Activity Relationship; Xanthines	1992
Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. Journal of medicinal chemistry, 1989, Volume: 32, Issue:8 Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; In Vitro Techniques; Radioligand Assay; Rats; Receptors, Purinergic; Structure-Activity Relationship; Sulfur; Xanthines	1989
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor. The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51 Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity	1994
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines	1994
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. British journal of pharmacology, 1997, Volume: 121, Issue:3 Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles	1997
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Biophysical mapping of the adenosine A2A receptor. Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13 Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Drug Design; Ligands; Models, Molecular; Mutation; Pyrimidines; Receptor, Adenosine A2A; Small Molecule Libraries; Triazines; Triazoles; Xanthines	2011
Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding. Biochemical pharmacology, 1992, Feb-18, Volume: 43, Issue:4 Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Injections, Intraperitoneal; Locomotion; Male; Mice; Receptors, Purinergic; Theophylline; Time Factors; Xanthines	1992
Chemical modification and irreversible inhibition of striatal A2a adenosine receptors. Molecular pharmacology, 1992, Volume: 42, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Amino Acid Sequence; Animals; Corpus Striatum; Diethyl Pyrocarbonate; Drug Antagonism; Hydroxylamine; Hydroxylamines; Molecular Sequence Data; Phenethylamines; Purinergic Antagonists; Rabbits; Radioligand Assay; Receptors, Purinergic; Theophylline; Xanthines	1992
A2 and P2 purine receptor interactions and surfactant secretion in primary cultures of type II cells. The American journal of physiology, 1991, Volume: 261, Issue:2 Pt 1 Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); AMP Deaminase; Animals; Cells, Cultured; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Lung; Phosphatidylcholines; Pulmonary Surfactants; Receptors, Purinergic; Terbutaline; Theophylline; Thionucleotides; Xanthines	1991
Activation of brain adenosine receptors evokes vasodilation in skin arterioles. The American journal of physiology, 1991, Volume: 261, Issue:2 Pt 2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Brain; Cricetinae; Injections, Intraventricular; Male; Mesocricetus; Receptors, Purinergic; Skin; Theophylline; Vasodilation; Vasodilator Agents; Xanthines	1991
Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC). Life sciences, 1989, Volume: 45, Issue:8 Topics: Animals; Caffeine; Convulsants; Diazepam; Dipyridamole; Male; Mice; Purinergic Antagonists; Random Allocation; Seizures; Theophylline; Xanthines	1989
Further characterization of the renovascular effects of N6-cyclohexyladenosine in the isolated perfused rat kidney. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:3 Topics: Adenosine; Animals; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Theophylline; Vasoconstriction; Xanthines	1987
Combined effect of adenosine, alpha adrenergic and adenosine antagonists on serum insulin and insulin secretion from rat pancreatic islets. The International journal of biochemistry, 1994, Volume: 26, Issue:3 Topics: Adenosine; Animals; Drug Interactions; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Prazosin; Rats; Rats, Wistar; Theophylline; Xanthines; Yohimbine	1994
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1 Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines	1999