Page last updated: 2024-08-16

8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and phenylisopropyladenosine

8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine has been researched along with phenylisopropyladenosine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (61.54)18.2507
2000's5 (38.46)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; van Galen, PJ; Williams, M1
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J1
Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD1
Jacobson, KA; Olah, ME; Stiles, GL1
Jacobson, MA; Johnson, RG; Linden, J; Salvatore, CA; Taylor, HE1
Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T1
Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K1
Barili, PL; Betti, L; Ferrarini, PL; Giannaccini, G; Lucacchini, A; Manera, C; Martinelli, A; Mori, C; Mori, F; Saccomanni, G; Trincavelli, L1
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW1
Ahern, DG; Jacobson, KA; Ji, X; Kim, YC; Linden, J1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1

Reviews

1 review(s) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and phenylisopropyladenosine

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

12 other study(ies) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and phenylisopropyladenosine

ArticleYear
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship

1995
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity

1994
Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.
    The Journal of biological chemistry, 1994, Oct-07, Volume: 269, Issue:40

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Binding Sites; Cattle; Cells, Cultured; Molecular Sequence Data; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Structure-Activity Relationship; Xanthines

1994
Molecular cloning and characterization of the human A3 adenosine receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Nov-01, Volume: 90, Issue:21

    Topics: Adenosine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Consensus Sequence; Corpus Striatum; Cricetinae; DNA Primers; Gene Expression; Humans; Iodobenzenes; Kinetics; Liver; Lung; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Sheep; Transfection

1993
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
    British journal of pharmacology, 1997, Volume: 121, Issue:3

    Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles

1997
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines

1998
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
    Molecular pharmacology, 1999, Volume: 56, Issue:4

    Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines

1999
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
    Molecular pharmacology, 2000, Volume: 57, Issue:5

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium

2000
A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: Adenylyl Cyclases; Animals; Cattle; Cerebral Cortex; Corpus Striatum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Naphthyridines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Structure-Activity Relationship

2000
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
    Molecular pharmacology, 2000, Volume: 58, Issue:6

    Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine

2000
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
    Biochemical pharmacology, 2001, Mar-15, Volume: 61, Issue:6

    Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007