Compounds > 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

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8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and caffeine

8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine has been researched along with caffeine in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (6.67)	18.7374
1990's	6 (40.00)	18.2507
2000's	4 (26.67)	29.6817
2010's	4 (26.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ishii, A; Karasawa, A; Kawakita, T; Kubo, K; Mizumoto, H; Nonaka, H; Shimada, J; Suzuki, F	1
Ichikawa, S; Ishii, A; Nonaka, H; Shimada, J; Suzuki, F	1
Jacobson, KA; van Galen, PJ; Williams, M	1
Jacobson, KA; Ji, XD; Kim, HO; Melman, N; Olah, ME; Stiles, GL	1
Ishiyama, H; Kobayashi, J; Nakata, H; Ohshita, K; Oyanagi, K	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Abe, T; Ishiyama, H; Kobayashi, J; Nakata, H; Ohshita, K	1
Ishiyama, H; Kobayashi, J; Nakajima, H; Nakata, H	1
Andrews, SP; Congreve, M; Errey, JC; Marshall, FH; Mason, JS; Robertson, N; Tehan, B; Weir, M; Zhukov, A	1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L	1
Capuano, B; Jörg, M; Mak, FS; Miller, ND; Scammells, PJ; Shonberg, J; Yuriev, E	1
Holtzman, SG; Mante, S; Minneman, KP	1
Daly, JW; Deckert, J; Jacobson, KA; Marangos, PJ; Morgan, PF	1
Richardt, G; Schreieck, J	1
Bennett, K; Congreve, M; Doré, AS; Errey, JC; Hollenstein, K; Hurrell, E; Magnani, F; Marshall, FH; Ng, I; Robertson, N; Tate, CG; Tehan, B; Weir, M	1

Reviews

2 review(s) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and caffeine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Fluorescent ligands for adenosine receptors. Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1 Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1	2013

Other Studies

13 other study(ies) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and caffeine

Article	Year
Adenosine A1 antagonists. 2. Structure-activity relationships on diuretic activities and protective effects against acute renal failure. Journal of medicinal chemistry, 1992, Aug-07, Volume: 35, Issue:16 Topics: Acute Kidney Injury; Adenosine; Animals; Cations, Monovalent; Diuretics; Male; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium; Structure-Activity Relationship; Xanthines	1992
(E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists. Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Corpus Striatum; Guinea Pigs; Molecular Structure; Prosencephalon; Purinergic Antagonists; Rats; Structure-Activity Relationship; Xanthines	1992
Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. Journal of medicinal chemistry, 1994, Sep-30, Volume: 37, Issue:20 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Brain Chemistry; Caffeine; CHO Cells; Cricetinae; Gene Expression; Iodine Radioisotopes; Molecular Structure; Phenethylamines; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Structure-Activity Relationship; Transfection; Xanthines	1994
Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors. Bioorganic & medicinal chemistry, 2007, May-01, Volume: 15, Issue:9 Topics: Binding Sites; Caffeine; Carbolines; Cell Line; Humans; Ligands; Molecular Structure; Receptors, Purinergic P1; Structure-Activity Relationship	2007
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Synthesis of eudistomin D analogues and its effects on adenosine receptors. Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7 Topics: Carbolines; Cell Line; Humans; Molecular Structure; Receptors, Purinergic P1; Structure-Activity Relationship	2008
Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors. Bioorganic & medicinal chemistry, 2009, Jul-01, Volume: 17, Issue:13 Topics: Binding, Competitive; Caffeine; Carbolines; Cell Line; Humans; Ligands; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship	2009
Biophysical mapping of the adenosine A2A receptor. Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13 Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Drug Design; Ligands; Models, Molecular; Mutation; Pyrimidines; Receptor, Adenosine A2A; Small Molecule Libraries; Triazines; Triazoles; Xanthines	2011
Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space. Bioorganic & medicinal chemistry letters, 2013, Jun-01, Volume: 23, Issue:11 Topics: Adenosine A2 Receptor Antagonists; Binding Sites; Humans; Hydrogen Bonding; Ligands; Molecular Docking Simulation; Protein Binding; Protein Structure, Tertiary; Receptor, Adenosine A2A; Triazines; Triazoles	2013
Role of adenosine receptors in caffeine tolerance. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Oral; Animals; Binding Sites; Brain; Caffeine; Cyclic AMP; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Time Factors; Tritium; Xanthines	1991
Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC). Life sciences, 1989, Volume: 45, Issue:8 Topics: Animals; Caffeine; Convulsants; Diazepam; Dipyridamole; Male; Mice; Purinergic Antagonists; Random Allocation; Seizures; Theophylline; Xanthines	1989
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart. Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1 Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines	1999
Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine. Structure (London, England : 1993), 2011, Sep-07, Volume: 19, Issue:9 Topics: Adenosine A2 Receptor Agonists; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Caffeine; Crystallography, X-Ray; HEK293 Cells; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Stability; Protein Structure, Tertiary; Receptor, Adenosine A2A; Surface Properties; Triazines; Triazoles; Xanthines	2011