8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.86) | 18.7374 |
1990's | 18 (51.43) | 18.2507 |
2000's | 11 (31.43) | 29.6817 |
2010's | 5 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Jacobson, KA; van Galen, PJ; Williams, M | 1 |
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J | 1 |
Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD | 1 |
Jacobson, KA; Olah, ME; Stiles, GL | 1 |
Jacobson, MA; Johnson, RG; Linden, J; Salvatore, CA; Taylor, HE | 1 |
Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C | 1 |
Glashofer, M; Jacobson, KA; Jiang, Q; Lee, BX; van Rhee, AM | 1 |
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C | 1 |
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T | 1 |
Baraldi, PG; Borea, PA; Cacciari, B; Gessi, S; Klotz, KN; Leung, E; Merighi, S; Romagnoli, R; Spalluto, G; Varani, K | 1 |
Barili, PL; Betti, L; Ferrarini, PL; Giannaccini, G; Lucacchini, A; Manera, C; Martinelli, A; Mori, C; Mori, F; Saccomanni, G; Trincavelli, L | 1 |
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW | 1 |
Ahern, DG; Jacobson, KA; Ji, X; Kim, YC; Linden, J | 1 |
Barak, D; Chen, A; Gao, ZG; Jacobson, KA; Kim, SA; Lee, K; Liang, BT; Link, A; Rompaey, PV; van Calenbergh, S | 1 |
Castelhano, AL; Ma, C; MacLennan, SJ; McKibben, B; Song, JP; Steinig, AG; Stewart, M | 1 |
Ishiyama, H; Kobayashi, J; Nakata, H; Ohshita, K; Oyanagi, K | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Abe, T; Ishiyama, H; Kobayashi, J; Nakata, H; Ohshita, K | 1 |
Ishiyama, H; Kobayashi, J; Nakajima, H; Nakata, H | 1 |
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L | 1 |
Handa, C; Momose, T; Muranaka, H; Ozawa, T | 1 |
Gobran, LI; Griese, M; Rooney, SA | 3 |
Jacobson, KA; Ji, XD; Stiles, GL | 1 |
Holtzman, SG; Mante, S; Minneman, KP | 1 |
Bealer, SL; Proctor, KG; Stojanov, I | 1 |
Klotz, KN; Lohse, MJ; Schwabe, U | 1 |
Prostran, M; Varagić, VM | 1 |
Nakata, H; Saitoh, O; Saitoh, Y | 1 |
Basavappa, S; Fitz, JG; Mangel, AW; McGill, JM; Middleton, JP; Shimokura, GH | 1 |
Bourgoin, S; Cesselin, F; Hamon, M; Mauborgne, A; Poliénor, H | 1 |
Briddon, SJ; Hill, SJ; May, LT | 1 |
Adams, L; Baker, JG; Briddon, SJ; Hill, SJ; Kellam, B; May, LT; Middleton, R | 1 |
Briddon, SJ; Bridge, LJ; Hill, SJ; May, LT; Stoddart, LA | 1 |
2 review(s) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)
Article | Year |
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Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
Fluorescent ligands for adenosine receptors.
Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 2013 |
33 other study(ies) available for 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine and adenosine-5'-(n-ethylcarboxamide)
Article | Year |
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Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship | 1995 |
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity | 1994 |
Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Binding Sites; Cattle; Cells, Cultured; Molecular Sequence Data; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Structure-Activity Relationship; Xanthines | 1994 |
Molecular cloning and characterization of the human A3 adenosine receptor.
Topics: Adenosine; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Consensus Sequence; Corpus Striatum; Cricetinae; DNA Primers; Gene Expression; Humans; Iodobenzenes; Kinetics; Liver; Lung; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Sheep; Transfection | 1993 |
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles | 1997 |
Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; COS Cells; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Humans; Hydrogen-Ion Concentration; Iodobenzenes; Ligands; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptor, Adenosine A2A; Receptors, Biogenic Amine; Receptors, Purinergic P1; Structure-Activity Relationship; Xanthines | 1997 |
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines | 1998 |
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines | 1999 |
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Phenylurea Compounds; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Triazoles; Tritium | 2000 |
A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives.
Topics: Adenylyl Cyclases; Animals; Cattle; Cerebral Cortex; Corpus Striatum; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Naphthyridines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Structure-Activity Relationship | 2000 |
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2000 |
[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.
Topics: Acetamides; Cells, Cultured; Humans; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Radiopharmaceuticals; Receptor, Adenosine A2B; Tritium | 2001 |
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
Topics: Adenosine; Amines; Animals; Cell Line; Cerebral Cortex; Cyclic AMP; GTP-Binding Proteins; Humans; In Vitro Techniques; Ligands; Models, Molecular; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1 | 2001 |
[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors.
Topics: Adenosine A2 Receptor Antagonists; Cells, Cultured; Humans; Pyrimidines; Pyrroles; Radioligand Assay; Time Factors; Tritium | 2004 |
Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors.
Topics: Binding Sites; Caffeine; Carbolines; Cell Line; Humans; Ligands; Molecular Structure; Receptors, Purinergic P1; Structure-Activity Relationship | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis of eudistomin D analogues and its effects on adenosine receptors.
Topics: Carbolines; Cell Line; Humans; Molecular Structure; Receptors, Purinergic P1; Structure-Activity Relationship | 2008 |
Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors.
Topics: Binding, Competitive; Caffeine; Carbolines; Cell Line; Humans; Ligands; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship | 2009 |
Photoaffinity Labeling of the Human A
Topics: | 2017 |
Cibacron blue stimulation of surfactant secretion in rat type II pneumocytes.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; L-Lactate Dehydrogenase; Lung; Phosphatidylcholines; Protein Synthesis Inhibitors; Pulmonary Surfactants; Rats; Second Messenger Systems; Stimulation, Chemical; Suramin; Terbutaline; Triazines; Xanthines | 1992 |
Chemical modification and irreversible inhibition of striatal A2a adenosine receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Amino Acid Sequence; Animals; Corpus Striatum; Diethyl Pyrocarbonate; Drug Antagonism; Hydroxylamine; Hydroxylamines; Molecular Sequence Data; Phenethylamines; Purinergic Antagonists; Rabbits; Radioligand Assay; Receptors, Purinergic; Theophylline; Xanthines | 1992 |
A2 and P2 purine receptor interactions and surfactant secretion in primary cultures of type II cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); AMP Deaminase; Animals; Cells, Cultured; Cyclic AMP; Inositol 1,4,5-Trisphosphate; Lung; Phosphatidylcholines; Pulmonary Surfactants; Receptors, Purinergic; Terbutaline; Theophylline; Thionucleotides; Xanthines | 1991 |
Role of adenosine receptors in caffeine tolerance.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Oral; Animals; Binding Sites; Brain; Caffeine; Cyclic AMP; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Time Factors; Tritium; Xanthines | 1991 |
Activation of brain adenosine receptors evokes vasodilation in skin arterioles.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Brain; Cricetinae; Injections, Intraventricular; Male; Mesocricetus; Receptors, Purinergic; Skin; Theophylline; Vasodilation; Vasodilator Agents; Xanthines | 1991 |
Mechanism of A2 adenosine receptor activation. I. Blockade of A2 adenosine receptors by photoaffinity labeling.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Alprostadil; Azides; Blood Platelets; Humans; Kinetics; Membranes; Phenylisopropyladenosine; Purinergic Antagonists; Radioligand Assay; Receptors, Purinergic; Tritium; Vasodilator Agents; Xanthines | 1991 |
The effect of 5'-N-ethylcarboxamideadenosine on the isolated hemidiaphragm of the rat during direct and indirect electrical stimulation.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminophylline; Animals; Diaphragm; Dipyridamole; Electric Stimulation; Female; In Vitro Techniques; Isometric Contraction; Male; Neuromuscular Blocking Agents; Rats; Receptors, Purinergic; Respiratory Muscles; Tubocurarine; Xanthines | 1989 |
Regulation of A2a adenosine receptor mRNA expression by agonists and forskolin in PC12 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; PC12 Cells; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; RNA, Messenger; Second Messenger Systems; Xanthines | 1994 |
Adenosine triphosphate activates ion permeabilities in biliary epithelial cells.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Bile Duct Neoplasms; Bile Ducts; Calcium; Cell Membrane Permeability; Cells, Cultured; Chlorides; Cholangiocarcinoma; Humans; Iodine Radioisotopes; Ion Transport; Male; Potassium; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Tumor Cells, Cultured; Uridine Triphosphate; Xanthines | 1994 |
Signal-transduction mechanisms of ATP-stimulated phosphatidylcholine secretion in rat type II pneumocytes: interactions between ATP and other surfactant secretagogues.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Drug Interactions; Ionomycin; Isoquinolines; L-Lactate Dehydrogenase; Lung; Male; Phosphatidylcholines; Piperazines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfonamides; Terbutaline; Tetradecanoylphorbol Acetate; Xanthines | 1993 |
Adenosine receptor-mediated control of in vitro release of pain-related neuropeptides from the rat spinal cord.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcitonin Gene-Related Peptide; Cholecystokinin; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Neuropeptides; Pain; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Spinal Cord; Substance P; Xanthines | 2002 |
Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Allosteric Regulation; Animals; Azo Compounds; Calcium; CHO Cells; Cricetinae; Cricetulus; Humans; Receptor, Adenosine A1; Receptor, Adenosine A3; Xanthines | 2010 |
Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.
Topics: Adenosine-5'-(N-ethylcarboxamide); Alkaline Phosphatase; Animals; Boron Compounds; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dansyl Compounds; Fluorescent Dyes; Genes, Reporter; GPI-Linked Proteins; Humans; Isoenzymes; Ligands; Microscopy, Confocal; Molecular Imaging; Molecular Probe Techniques; Molecular Structure; Radioligand Assay; Receptor, Adenosine A1; Response Elements; Transfection; Xanthines | 2010 |
Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Allosteric Regulation; Animals; CHO Cells; Cricetinae; Cricetulus; Gene Expression Regulation; Humans; Kinetics; Protein Binding; Receptor, Adenosine A3; Xanthines | 2011 |