Page last updated: 2024-09-03

8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline and carmustine

8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline has been researched along with carmustine in 2 studies

*Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) [MeSH]

*Carmustine: A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) [MeSH]

Compound Research Comparison

Studies
(8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline)
Trials
(8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline)
Recent Studies (post-2010)
(8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline)
Studies
(carmustine)
Trials
(carmustine)
Recent Studies (post-2010) (carmustine)
263124,168686540

Protein Interaction Comparison

ProteinTaxonomy8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline (IC50)carmustine (IC50)
Glutathione reductase, mitochondrialHomo sapiens (human)8.1

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmad, T; Frischer, H; Mellovitz, RL; Nora, MV1
Ahmad, T; Carson, PE; Chow, HS; Frischer, H; Kaizer, H; Mellovitz, R; Nora, MV; Parkhurst, GW; Ptak, L; Sivarajan, M1

Other Studies

2 other study(ies) available for 8-(3-carboxy-1-methylpropylamino)-6-methoxyquinoline and carmustine

ArticleYear
The conversion of primaquine into primaquine-aldehyde, primaquine-alcohol, and carboxyprimaquine, a major plasma metabolite.
    The Journal of laboratory and clinical medicine, 1991, Volume: 117, Issue:6

    Topics: Alcohols; Aldehydes; Biotransformation; Blood; Bone Marrow; Bone Marrow Cells; Carmustine; Chromatography; Chromatography, High Pressure Liquid; Embryo, Mammalian; Humans; Leukemia, Erythroblastic, Acute; Liver; Primaquine; Tumor Cells, Cultured

1991
Biotransformation of primaquine in vitro with human K562 and bone marrow cells.
    The Journal of laboratory and clinical medicine, 1987, Volume: 109, Issue:4

    Topics: Biotransformation; Bone Marrow; Carmustine; Cell Line; Cells, Cultured; Chromatography, High Pressure Liquid; Humans; Primaquine

1987