Compounds > 7h-pyrido(4,3-c)carbazole
Page last updated: 2024-09-03

7h-pyrido(4,3-c)carbazole and astemizole

7h-pyrido(4,3-c)carbazole has been researched along with astemizole in 2 studies

Compound Research Comparison

Studies
(7h-pyrido(4,3-c)carbazole)		Trials
(7h-pyrido(4,3-c)carbazole)		Recent Studies (post-2010)
(7h-pyrido(4,3-c)carbazole)		Studies
(astemizole)		Trials
(astemizole)		Recent Studies (post-2010) (astemizole)
6011,130117578

Protein Interaction Comparison

ProteinTaxonomy7h-pyrido(4,3-c)carbazole (IC50)astemizole (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.1
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.179
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)6.057
Tyrosine-protein kinase FynHomo sapiens (human)2.847
ATP-dependent translocase ABCB1Mus musculus (house mouse)1.7
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.375
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.409
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.861
ATP-dependent translocase ABCB1Homo sapiens (human)0.9667
Cytochrome P450 3A4Homo sapiens (human)3.3
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.703
Alpha-2A adrenergic receptorHomo sapiens (human)4.846
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.066
Beta-3 adrenergic receptorHomo sapiens (human)8.06
D(2) dopamine receptorHomo sapiens (human)4.521
Alpha-2B adrenergic receptorHomo sapiens (human)3.839
Alpha-2C adrenergic receptorHomo sapiens (human)1.959
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.767
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.84
ATP-dependent translocase ABCB1Mus musculus (house mouse)1.3
Substance-K receptorHomo sapiens (human)2.986
D(1A) dopamine receptorHomo sapiens (human)4.01
D(4) dopamine receptorHomo sapiens (human)6.087
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.375
Histamine H2 receptorHomo sapiens (human)1.682
Alpha-1D adrenergic receptorHomo sapiens (human)0.769
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.02
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.179
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.767
Sodium-dependent serotonin transporterHomo sapiens (human)1.318
Melanocortin receptor 5Homo sapiens (human)2.263
Histamine H1 receptorHomo sapiens (human)0.014
Mu-type opioid receptorHomo sapiens (human)1.492
D(3) dopamine receptorHomo sapiens (human)0.436
Kappa-type opioid receptorHomo sapiens (human)6.616
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.012
5-hydroxytryptamine receptor 6Homo sapiens (human)3.266
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.1
Sodium-dependent dopamine transporter Homo sapiens (human)0.998
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2857
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.1
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.1
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.246

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adrián, F; Anderson, P; Brinker, A; Caldwell, JS; Chatterjee, A; Gray, NS; Henson, K; Janes, J; Kato, N; Kuhen, K; Matzen, JT; McNamara, C; Nagle, A; Nam, TG; Plouffe, D; Schultz, PG; Trager, R; Winzeler, EA; Yan, SF; Zhou, Y1
Barnes, SW; Bonamy, GM; Bopp, SE; Borboa, R; Bright, AT; Chatterjee, A; Che, J; Cohen, S; Dharia, NV; Diagana, TT; Fidock, DA; Froissard, P; Gagaring, K; Gettayacamin, M; Glynne, RJ; Gordon, P; Groessl, T; Kato, N; Kuhen, KL; Lee, MC; Mazier, D; McNamara, CW; Meister, S; Nagle, A; Nam, TG; Plouffe, DM; Richmond, W; Roland, J; Rottmann, M; Sattabongkot, J; Schultz, PG; Tuntland, T; Walker, JR; Winzeler, EA; Wu, T; Zhou, B; Zhou, Y1

Other Studies

2 other study(ies) available for 7h-pyrido(4,3-c)carbazole and astemizole

ArticleYear
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Jul-01, Volume: 105, Issue:26

    Topics: Animals; Antimalarials; Cluster Analysis; Computational Biology; Drug Evaluation, Preclinical; Drug Resistance; Folic Acid Antagonists; Malaria; Models, Molecular; Parasites; Plasmodium falciparum; Reproducibility of Results; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase

2008
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.
    Science (New York, N.Y.), 2011, Dec-09, Volume: 334, Issue:6061

    Topics: Animals; Antimalarials; Cell Line, Tumor; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance; Erythrocytes; Humans; Imidazoles; Liver; Malaria; Mice; Mice, Inbred BALB C; Molecular Structure; Piperazines; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Polymorphism, Single Nucleotide; Protozoan Proteins; Random Allocation; Small Molecule Libraries; Sporozoites

2011