7432-s has been researched along with cefuroxime-axetil* in 3 studies
1 review(s) available for 7432-s and cefuroxime-axetil
| Article | Year |
|---|---|
The role of newer oral cephalosporins, fluoroquinolones, and macrolides in the treatment of pediatric infections.
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Bacterial Infections; Cefixime; Cefotaxime; Cefpodoxime Proxetil; Cefprozil; Ceftibuten; Ceftizoxime; Cefuroxime; Cephalosporins; Child; Clarithromycin; Fluoroquinolones; Humans | 1994 |
2 other study(ies) available for 7432-s and cefuroxime-axetil
| Article | Year |
|---|---|
[Comparative clinical efficacy and tolerance of cefuroxime axetil (zinnat) and ceftibuten (cedex) in patients with acute sinusitis].
The aim of the study was to substantiate clinically and microbiologically administration of such oral cephalosporins as cefuroxime axetil and ceftibuten in acute sinusitis. The spectrum of causative agents of acute sinusitis was determined, most common pathogens were identified and their sensitivity to antibiotics was tested. The conclusion is made that cephalosporins of the II-III generation meet the requirements to antibacterial drugs for treatment of acute sinusitis. Topics: Acute Disease; Adult; Ceftibuten; Cefuroxime; Cephalosporins; Drug Tolerance; Female; Humans; Male; Sinusitis; Treatment Outcome | 2001 |
The relationship between an increase in beta-lactamase activity after oral administration of three new cephalosporins and protection against intestinal ecological disturbances.
Forty-four healthy volunteers were given either amoxycillin (ten subjects), cefpodoxime proxetil (ten subjects), ceftibuten (14 subjects) or cefuroxime axetil (ten subjects) orally for 7-10 days, in order to study the ecological effects on the intestinal microflora. In all three groups receiving oral cephalosporins there was a significant increase in beta-lactamase activity during administration (P < 0.05). There was also an inverse correlation between enzyme activity in faeces during administration compared with the concentration of drug in the intestines and the level of ecological disturbance in the normal intestinal microflora. In volunteers given amoxycillin, only small alterations in the faecal microflora were observed although overgrowth by new amoxycillin resistant enterobacteria occurred in all volunteers. There was an overgrowth of enterococci and yeasts during treatment with cefpodoxime proxetil, ceftibuten or cefuroxime axetil, whereas the numbers of enterobacteria were reduced. Colonization with resistant enterobacteria did not occur, but 14 of 34 subjects receiving oral cephalosporins were colonized by Clostridium difficile. Side-effects were mild and not associated with the ecological alterations in the intestinal microflora. Topics: Administration, Oral; Adult; Amoxicillin; beta-Lactamases; Cefpodoxime Proxetil; Ceftibuten; Ceftizoxime; Cefuroxime; Cephalosporins; Feces; Female; Humans; Intestines; Male; Middle Aged; Prodrugs | 1994 |