7-thiomethylspirolactone has been researched along with canrenone in 11 studies
| Studies (7-thiomethylspirolactone) | Trials (7-thiomethylspirolactone) | Recent Studies (post-2010) (7-thiomethylspirolactone) | Studies (canrenone) | Trials (canrenone) | Recent Studies (post-2010) (canrenone) |
|---|---|---|---|---|---|
| 13 | 4 | 1 | 268 | 39 | 59 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Gadsden, RH; Pleasants, RA; Porter, RS; Williams, DM | 1 |
| Colby, HD; O'Donnell, JP; Sherry, JH | 1 |
| Hermens, WA; Merkus, FW; Overdiek, JW | 1 |
| Hermens, WA; Merkus, FW; Overdiek, HW | 1 |
| Colby, HD; Los, LE | 1 |
| Jankowski, A; Lamparczyk, H; Skorek-Jankowska, A | 1 |
| Abosehmah-Albidy, AZ; Chrystyn, H; Losowsky, MS; Wong, V; York, P | 1 |
| Eichinger, A; Mahr, G; Martens, H; Metz, R; Nitsche, V; Vergin, H | 1 |
| Eichinger, A; Mahr, G; Metz, R; Nitsche, V; Vergin, H | 1 |
| Collier, PS; McElnay, JC; Millership, JS; Sandall, JM | 1 |
| Behar-Cohen, F; Dahmana, N; Gabriel, D; Gurny, R; Kalia, YN; Kowalczuk, L | 1 |
3 trial(s) available for 7-thiomethylspirolactone and canrenone
| Article | Year |
|---|---|
Improved bioavailability and clinical response in patients with chronic liver disease following the administration of a spironolactone: beta-cyclodextrin complex.
Topics: beta-Cyclodextrins; Biological Availability; Canrenone; Chronic Disease; Cross-Over Studies; Cyclodextrins; Diuresis; Diuretics; Female; Humans; Liver Diseases; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Spironolactone; Treatment Outcome; Water-Electrolyte Balance | 1997 |
Analysis of metabolites--a new approach to bioequivalence studies of spironolactone formulations.
Topics: Administration, Oral; Adult; Analysis of Variance; Canrenone; Cross-Over Studies; Humans; Male; Mineralocorticoid Receptor Antagonists; Spironolactone; Therapeutic Equivalency; Time Factors | 1997 |
Investigation on the bioequivalence of 2 oral preparations containing spironolactone and furosemide.
Topics: Adult; Area Under Curve; Canrenone; Chromatography, High Pressure Liquid; Diuretics; Furosemide; Humans; Male; Mineralocorticoid Receptor Antagonists; Spironolactone; Therapeutic Equivalency | 1998 |
8 other study(ies) available for 7-thiomethylspirolactone and canrenone
| Article | Year |
|---|---|
Reassessment of cross-reactivity of spironolactone metabolites with four digoxin immunoassays.
Topics: Adult; Canrenone; Cross Reactions; Digoxin; Humans; Immunoassay; Immunoenzyme Techniques; Male; Radioimmunoassay; Spironolactone | 1989 |
Separation of spironolactone and its biologically active sulfur-containing metabolites by high-performance liquid chromatography.
Topics: Animals; Canrenone; Chromatography, High Pressure Liquid; Guinea Pigs; Male; Mass Spectrometry; Spironolactone | 1986 |
Determination of the serum concentration of spironolactone and its metabolites by high-performance liquid chromatography.
Topics: Canrenone; Chromatography, High Pressure Liquid; Humans; Spectrophotometry, Ultraviolet; Spironolactone | 1985 |
New insights into the pharmacokinetics of spironolactone.
Topics: Absorption; Administration, Oral; Adult; Biotransformation; Canrenone; Half-Life; Humans; Kinetics; Male; Spironolactone | 1985 |
Binding of spironolactone metabolites in vivo to renal mineralocorticoid receptors in guinea pigs.
Topics: Aldosterone; Animals; Binding, Competitive; Canrenone; Guinea Pigs; Kidney; Male; Receptors, Mineralocorticoid; Spironolactone | 1994 |
Simultaneous determination of spironolactone and its metabolites in human plasma.
Topics: Canrenone; Chromatography, High Pressure Liquid; Humans; Osmolar Concentration; Reproducibility of Results; Spectrophotometry, Ultraviolet; Spironolactone | 1996 |
Development and validation of an HPLC method for the determination of spironolactone and its metabolites in paediatric plasma samples.
Topics: Canrenone; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Drug Stability; Humans; Reference Standards; Reproducibility of Results; Spironolactone; Time Factors | 2006 |
Ocular Biodistribution of Spironolactone after a Single Intravitreal Injection of a Biodegradable Sustained-Release Polymer in Rats.
Topics: Animals; Canrenone; Chromatography, Liquid; Delayed-Action Preparations; Fundus Oculi; Intravitreal Injections; Mass Spectrometry; Polyesters; Rats; Rats, Wistar; Retina; Spironolactone; Time Factors; Tissue Distribution; Tomography, Optical Coherence | 2020 |