7-propyl spirolactone has been researched along with mifepristone in 6 studies
| Studies (7-propyl spirolactone) | Trials (7-propyl spirolactone) | Recent Studies (post-2010) (7-propyl spirolactone) | Studies (mifepristone) | Trials (mifepristone) | Recent Studies (post-2010) (mifepristone) |
|---|---|---|---|---|---|
| 31 | 0 | 0 | 6,536 | 595 | 1,758 |
| Protein | Taxonomy | 7-propyl spirolactone (IC50) | mifepristone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Canis lupus familiaris (dog) | 0.0264 | |
| Bile salt export pump | Homo sapiens (human) | 2.02 | |
| Estrogen receptor | Homo sapiens (human) | 4.311 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.0249 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.0003 | |
| Progesterone receptor | Homo sapiens (human) | 0.1347 | |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.774 | |
| Glucocorticoid receptor | Mus musculus (house mouse) | 0.0022 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 2.0938 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 9.5 | |
| Coagulation factor VII | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Homo sapiens (human) | 0.2988 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 1.5 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4.9 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 0.0016 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.555 | |
| Tissue factor | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0083 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0014 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.0022 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0078 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Mu-type opioid receptor | Homo sapiens (human) | 2.457 | |
| Estrogen receptor beta | Homo sapiens (human) | 1.528 | |
| Glucocorticoid receptor | Sus scrofa (pig) | 0.0153 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davda, MM; Kang, CG; Luttge, WG; Rupp, ME | 1 |
| Boadle-Biber, MC; Corley, KC; Krieg, RJ; Phan, TH; Singh, VB | 1 |
| Ricketts, ML; Stewart, PM; Whorwood, CB | 1 |
| Barker, KS; Davis, AT; Rollins-Smith, LA | 1 |
| Cluzeaud, F; Le Menuet, D; Lombès, M; Penfornis, P; Viengchareun, S; Zennaro, MC | 1 |
| Coca-Prados, M; Hewison, M; Hughes, SV; Murray, PI; Rauz, S; Stewart, PM; Walker, EA | 1 |
6 other study(ies) available for 7-propyl spirolactone and mifepristone
| Article | Year |
|---|---|
High affinity binding and regulatory actions of dexamethasone-type I receptor complexes in mouse brain.
Topics: Aldosterone; Animals; Brain; Cytosol; Dexamethasone; DNA-Binding Proteins; Estrenes; Female; Glucocorticoids; Kinetics; Mice; Mifepristone; Organ Specificity; Receptors, Glucocorticoid; Spironolactone | 1989 |
Sound stress activation of tryptophan hydroxylase blocked by hypophysectomy and intracranial RU 38486.
Topics: Acoustic Stimulation; Animals; Cerebral Cortex; Dexamethasone; Enzyme Activation; Hypophysectomy; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Mesencephalon; Mifepristone; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Spironolactone; Stress, Psychological; Tryptophan Hydroxylase | 1994 |
Regulation of sodium-potassium adenosine triphosphate subunit gene expression by corticosteroids and 11 beta-hydroxysteroid dehydrogenase activity.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Animals; Gene Expression Regulation; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hydroxysteroid Dehydrogenases; Kidney; Male; Mifepristone; Rats; Rats, Wistar; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone | 1994 |
Involvement of glucocorticoids in the reorganization of the amphibian immune system at metamorphosis.
Topics: Aldosterone; Animals; Apoptosis; Corticosterone; Glucocorticoids; Hormone Antagonists; Lymphocyte Activation; Lymphocytes; Metamorphosis, Biological; Mifepristone; Spironolactone; Spleen; Thymus Gland; Xenopus laevis | 1997 |
The mineralocorticoid receptor mediates aldosterone-induced differentiation of T37i cells into brown adipocytes.
Topics: Adipose Tissue, Brown; Aldosterone; Animals; Carrier Proteins; Cell Differentiation; Dose-Response Relationship, Drug; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Hormone Antagonists; Lipoma; Lipoprotein Lipase; Mice; Mifepristone; Mineralocorticoid Receptor Antagonists; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Receptors, Cytoplasmic and Nuclear; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Transcription Factors; Transcription, Genetic; Triglycerides; Tumor Cells, Cultured | 2000 |
Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium.
Topics: Aldosterone; Blotting, Northern; Cell Line; Ciliary Body; Dexamethasone; Dose-Response Relationship, Drug; Drug Combinations; Epithelial Sodium Channels; Gene Expression Regulation; Glucocorticoids; Hormone Antagonists; Humans; Immediate-Early Proteins; In Situ Hybridization; Isoenzymes; Mifepristone; Mineralocorticoid Receptor Antagonists; Nuclear Proteins; Pigment Epithelium of Eye; Protein Serine-Threonine Kinases; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Spironolactone | 2003 |