7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine has been researched along with 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole in 1 studies
*3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source [MeSH]
*3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source [MeSH]
| Studies (7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine) | Trials (7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine) | Recent Studies (post-2010) (7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine) | Studies (3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole) | Trials (3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole) | Recent Studies (post-2010) (3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole) |
|---|---|---|---|---|---|
| 6 | 1 | 3 | 377 | 2 | 154 |
| Protein | Taxonomy | 7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine (IC50) | 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole (IC50) |
|---|---|---|---|
| Histone acetyltransferase p300 | Homo sapiens (human) | 1.3 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 2.935 | |
| CREB-binding protein | Homo sapiens (human) | 1.3 | |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | 1.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SG; Lee, JM; Lee, YH; Lee, YS | 1 |
1 other study(ies) available for 7-methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine and 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole
| Article | Year |
|---|---|
Synthesis and biological evaluation of 1,2-dithiol-3-thiones and pyrrolo[1,2-a]pyrazines as novel hypoxia inducible factor-1 (HIF-1) inhibitor.
Topics: Antineoplastic Agents; Glucose Transporter Type 1; HCT116 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Pyrazines; Thiones; Thiophenes; Transcriptional Activation; Vascular Endothelial Growth Factor A | 2016 |