7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2-3-dihydro-1h-indol-5-yl)-7h-pyrrolo(2-3-d)pyrimidin-4-amine has been researched along with 3-methyladenine* in 1 studies
1 other study(ies) available for 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2-3-dihydro-1h-indol-5-yl)-7h-pyrrolo(2-3-d)pyrimidin-4-amine and 3-methyladenine
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Suppressing endoplasmic reticulum stress-related autophagy attenuates retinal light injury.
Excessive light exposure is a principal environmental factor, which can cause damage to photoreceptors and retinal pigment epithelium (RPE) cells and may accelerate the progression of age-related macular degeneration (AMD). In this study, oxidative stress, endoplasmic reticulum (ER) stress and autophagy caused by light exposure were evaluated Topics: Acetylcysteine; Adenine; Animals; Antioxidants; Autophagy; Cell Line; eIF-2 Kinase; Endoplasmic Reticulum Stress; Humans; Indoles; Light; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Photoreceptor Cells, Vertebrate; Retinal Pigment Epithelium | 2020 |