Page last updated: 2024-09-03

7-methoxytacrine and thiourea

7-methoxytacrine has been researched along with thiourea in 3 studies

Compound Research Comparison

Studies (7-methoxytacrine)	Trials (7-methoxytacrine)	Recent Studies (post-2010) (7-methoxytacrine)	Studies (thiourea)	Trials (thiourea)	Recent Studies (post-2010) (thiourea)
52	1	28	6,959	46	1,737

Protein Interaction Comparison

Protein	Taxonomy	thiourea (IC50)
Urease	Canavalia ensiformis (jack bean)	0.56
Serine-protein kinase ATM	Homo sapiens (human)	0.2
Serine/threonine-protein kinase ATR	Homo sapiens (human)	0.2

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ibrar, A; Khan, I; Saeed, F; Shehzadi, SA	1
Drtinova, L; Gazova, Z; Horova, A; Korabecny, J; Kral, J; Kuca, K; Musilek, K; Siposova, K; Soukup, O; Spilovska, K	1
Babkova, K; Brabec, V; Fedorocko, P; Hamulakova, S; Janockova, J; Jendzelovsky, R; Kasparkova, J; Konkolova, E; Korabecny, J; Koval, J; Kozurkova, M; Kuca, K; Kucerova, D; Plsikova, J; Rosocha, J; Soukup, O; Vargova, J	1

Reviews

1 review(s) available for 7-methoxytacrine and thiourea

Article	Year
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery. Bioorganic & medicinal chemistry, 2018, 07-30, Volume: 26, Issue:13 Topics: Aldehyde Reductase; Alkaline Phosphatase; Cholinesterases; Coumarins; Drug Design; Enzymes; Glucosidases; Humans; Molecular Docking Simulation; Monoamine Oxidase	2018

Other Studies

2 other study(ies) available for 7-methoxytacrine and thiourea

Article	Year
7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies. Molecules (Basel, Switzerland), 2013, Feb-20, Volume: 18, Issue:2 Topics: Acetylcholinesterase; Alzheimer Disease; Amantadine; Cholinesterase Inhibitors; Dimerization; Enzyme Assays; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Docking Simulation; Reference Standards; Tacrine; Thiourea	2013
In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers. Journal of enzyme inhibition and medicinal chemistry, 2019, Volume: 34, Issue:1 Topics: A549 Cells; Acridines; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; HL-60 Cells; Humans; Structure-Activity Relationship; Tacrine; Thiourea	2019

Article

Year

7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.

Molecules (Basel, Switzerland), 2013, Feb-20, Volume: 18, Issue:2

Topics: Acetylcholinesterase; Alzheimer Disease; Amantadine; Cholinesterase Inhibitors; Dimerization; Enzyme Assays; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Docking Simulation; Reference Standards; Tacrine; Thiourea

2013

In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.

Journal of enzyme inhibition and medicinal chemistry, 2019, Volume: 34, Issue:1

Topics: A549 Cells; Acridines; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; HL-60 Cells; Humans; Structure-Activity Relationship; Tacrine; Thiourea

2019