7-methoxytacrine has been researched along with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid in 2 studies
| Studies (7-methoxytacrine) | Trials (7-methoxytacrine) | Recent Studies (post-2010) (7-methoxytacrine) | Studies (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) | Trials (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) | Recent Studies (post-2010) (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid) |
|---|---|---|---|---|---|
| 52 | 1 | 28 | 1,541 | 16 | 580 |
| Protein | Taxonomy | 7-methoxytacrine (IC50) | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.13 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.15 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrs, M; Babkova, K; Bukum, N; Dolezal, R; Horova, A; Hrabinova, M; Jost, P; Jun, D; Kassa, J; Korabecny, J; Kuca, K; Malinak, D; Muckova, L; Nepovimova, E; Ondrejicek, A; Sepsova, V; Soukup, O | 1 |
| Bartolini, M; Bolognesi, ML; Guidotti, L; Hrabinova, M; Jeřábek, J; Korábečný, J; Kuča, K; Monti, B; Peña-Altamira, LE; Petralla, S; Roberti, M; Sepsova, V; Soukup, O; Uliassi, E | 1 |
2 other study(ies) available for 7-methoxytacrine and 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
| Article | Year |
|---|---|
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.
Topics: Acetylcholinesterase; Animals; Antioxidants; Blood-Brain Barrier; Catalysis; Cholinesterase Inhibitors; Chromans; Drug Design; Free Radical Scavengers; Hepatocytes; Humans; Injections, Intramuscular; Kinetics; Ligands; Male; Microsomes, Liver; Models, Molecular; Rats; Rats, Wistar; Tacrine | 2015 |
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Liver; Molecular Targeted Therapy; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats; Resveratrol; Stilbenes; Tacrine | 2017 |