7-methoxyresorufin has been researched along with ethoxyresorufin in 7 studies
Studies (7-methoxyresorufin) | Trials (7-methoxyresorufin) | Recent Studies (post-2010) (7-methoxyresorufin) | Studies (ethoxyresorufin) | Trials (ethoxyresorufin) | Recent Studies (post-2010) (ethoxyresorufin) |
---|---|---|---|---|---|
18 | 0 | 3 | 241 | 1 | 39 |
Protein | Taxonomy | 7-methoxyresorufin (IC50) | ethoxyresorufin (IC50) |
---|---|---|---|
Cytochrome P450 1A2 | Homo sapiens (human) | 0.5 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (57.14) | 18.2507 |
2000's | 2 (28.57) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hatano, M; Hiroya, K; Krainev, AG; Shimizu, T | 1 |
Lubet, RA; Nerurkar, PV; Nims, RW; Park, SS; Thomas, PE | 1 |
Cheung, YL; Gray, TJ; Ioannides, C | 1 |
Chun, YJ; Guengerich, FP; Jeong, TC; Roh, JK | 1 |
Paulsen, MD; Szklarz, GD | 1 |
Bursian, SJ; Giesy, JP; Hecker, M; Jones, PD; Moore, JN; Newsted, JL; Zhang, X; Zwiernik, MJ | 1 |
Henderson, CJ; Kapelyukh, Y; Rode, A; Scheer, N; Wolf, CR | 1 |
7 other study(ies) available for 7-methoxyresorufin and ethoxyresorufin
Article | Year |
---|---|
Effect of mutations at Lys250, Arg251, and Lys253 of cytochrome P450 1A2 on the catalytic activities and the bindings of bifunctional axial ligands.
Topics: Amino Acid Sequence; Animals; Arginine; Catalysis; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Kinetics; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxazines; Oxidoreductases; Protein Conformation; Spectrum Analysis; Structure-Activity Relationship | 1992 |
Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse.
Topics: Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mice; Microsomes; Oxazines; Oxidoreductases; Rats; Rats, Inbred F344; Xenobiotics | 1993 |
Mutagenicity of chrysene, its methyl and benzo derivatives, and their interactions with cytochromes P-450 and the Ah-receptor; relevance to their carcinogenic potency.
Topics: Animals; Chrysenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxazines; Polychlorinated Dibenzodioxins; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1993 |
Characterization of a fusion protein between human cytochrome P450 1A1 and rat NADPH-P450 oxidoreductase in Escherichia coli.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; DNA, Complementary; Escherichia coli; Humans; Kinetics; NADPH-Ferrihemoprotein Reductase; Oxazines; Rats; Recombinant Fusion Proteins; Substrate Specificity | 1997 |
Molecular modeling of cytochrome P450 1A1: enzyme-substrate interactions and substrate binding affinities.
Topics: Amino Acid Sequence; Benzo(a)pyrene; Binding Sites; Computer Simulation; Crystallography, X-Ray; Cytochrome P-450 CYP1A1; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Oxazines; Protein Binding; Protein Structure, Secondary; Sequence Homology, Amino Acid; Substrate Specificity; Water | 2002 |
Sequencing and characterization of mixed function monooxygenase genes CYP1A1 and CYP1A2 of Mink (Mustela vison) to facilitate study of dioxin-like compounds.
Topics: Animals; Benzofurans; Blotting, Western; Cloning, Molecular; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Induction; Female; Kinetics; Liver; Mink; Oxazines; Phylogeny; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Substrate Specificity | 2009 |
Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Drug Evaluation, Preclinical; Gene Knock-In Techniques; Liver; Mice, Knockout; Models, Animal; Oxazines | 2019 |