7-ketocholesterol has been researched along with cholest-5-en-3 beta,7 alpha-diol, (3beta,7beta)-isomer in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carvalho, JF; Moreira, JN; Sá e Melo, ML; Silva, MM; Simões, S | 2 |
| Dodo, K; Hashimoto, Y; Karaki, F; Ohgane, K | 1 |
| Lizard, G; Nury, T; Riedinger, JM; Samadi, M; Zarrouk, A | 1 |
| Dodo, K; Hashimoto, Y; Karaki, F; Noguchi-Yachide, T; Ohgane, K | 1 |
5 other study(ies) available for 7-ketocholesterol and cholest-5-en-3 beta,7 alpha-diol, (3beta,7beta)-isomer
| Article | Year |
|---|---|
Sterols as anticancer agents: synthesis of ring-B oxygenated steroids, cytotoxic profile, and comprehensive SAR analysis.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Line, Tumor; Cell Proliferation; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Sterols; Structure-Activity Relationship | 2010 |
Selective cytotoxicity of oxysterols through structural modulation on rings A and B. Synthesis, in vitro evaluation, and SAR.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Sterols; Structure-Activity Relationship | 2011 |
Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.
Topics: Anticholesteremic Agents; Azetidines; Binding Sites; Biological Transport; Carbamates; Ezetimibe; HEK293 Cells; Humans; Ligands; Membrane Proteins; Membrane Transport Proteins; Mutation; Steroids; Structure-Activity Relationship | 2013 |
Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4α- and 4β-hydroxycholesterol) and C7 (7-ketocholesterol, 7α- and 7β-hydroxycholesterol) on cells of the central nervous system.
Topics: Cell Line; Cell Proliferation; Cell Survival; Central Nervous System; Dose-Response Relationship, Drug; Humans; Hydroxycholesterols; Ketocholesterols; Molecular Conformation; Oxidation-Reduction; Sterols; Structure-Activity Relationship | 2013 |
Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.
Topics: Carrier Proteins; Dose-Response Relationship, Drug; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Molecular Structure; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Sterols; Structure-Activity Relationship | 2014 |