7-hydroxymethyl-12-methylbenz(a)anthracene has been researched along with 9,10-dimethyl-1,2-benzanthracene in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (61.54) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bigger, CA; Dipple, A; Egan, M; Moschel, RC; Nebzydoski, JA; Tomaszewski, JE | 1 |
| Barnes, S; Coward, L; Falany, CN; Falany, JL; Keehan, D; Wheeler, J | 1 |
| Bandyopadhyay, AM; Banerjee, MR; Das, SK; Jia, TZ | 1 |
| Baldwin, DM; Hollingsworth, L; Vater, ST; Warshawsky, D | 1 |
| Liem, A; Miller, EC; Miller, JA; Surh, YJ | 3 |
| Hiratsuka, A; Ogura, K; Okuda, H; Sohtome, T; Sugiyama, A; Watabe, T | 1 |
| Hallberg, E; Rydström, J | 4 |
| Lai, CC; Miller, EC; Miller, JA; Surh, YJ | 1 |
| Christou, M; Gould, MN; Jefcoate, CR; Moore, CJ | 1 |
| Fujieda, T; Hakamata, Y; Hiratsuka, A; Ishizuka, T; Ogura, K; Watabe, T | 1 |
| Aizawa, T; Hakamata, Y; Ishizuka, T; Isobe, M; Watabe, T | 1 |
| Decina, PC; DiGiovanni, J; Nebzydoski, AP | 1 |
| Grover, PL; Pal, K; Phillips, DH; Sims, P; Swallow, WH | 1 |
| Christou, M; Jefcoate, CR; Wilson, NM | 1 |
| Cazer, FD; Hart, RW; Sheikh, YM; Witiak, DT | 1 |
| Chou, MW; Sydor, W; Yang, CS; Yang, SK | 1 |
| Ishizuka, T; Isobe, M; Ozawa, N; Watabe, T | 2 |
| Daniel, FB; Joyce, NJ | 1 |
| Flesher, JW; Horn, J; Lehner, AF | 1 |
| Flesher, JW; Gupta, RC; Horn, J; Vadhanam, MV | 1 |
1 review(s) available for 7-hydroxymethyl-12-methylbenz(a)anthracene and 9,10-dimethyl-1,2-benzanthracene
| Article | Year |
|---|---|
Electrophilic sulfuric acid ester metabolites of hydroxy-methyl aromatic hydrocarbons as precursors of hepatic benzylic DNA adducts in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA; Esters; Liver; Polycyclic Compounds; Rats; Sulfotransferases; Sulfuric Acids | 1991 |
25 other study(ies) available for 7-hydroxymethyl-12-methylbenz(a)anthracene and 9,10-dimethyl-1,2-benzanthracene
| Article | Year |
|---|---|
Comparison of metabolism-mediated binding to DNA of 7-hydroxymethyl-12-methylbenz(a)anthracene and 7, 12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cells, Cultured; Chemical Phenomena; Chemistry; DNA; Embryo, Mammalian; Epoxide Hydrolases; Epoxy Compounds; Hydrocarbons, Chlorinated; In Vitro Techniques; Mice; Microsomes, Liver; Rats; Spectrometry, Fluorescence | 1979 |
Bioactivation of 7-hydroxymethyl-12-methylbenz[a]anthracene by rat liver bile acid sulfotransferase I.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Cytosol; DNA; Female; Liver; Male; Rats; Rats, Sprague-Dawley; Sulfotransferases | 1992 |
beta-Carotene-mediated inhibition of a DNA adduct induced by 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene in mouse mammary gland in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C | 1992 |
Comparative metabolism of 7,12-dimethylbenz[a]anthracene by the perfused liver and liver microsomal preparations from Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains | 1991 |
Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Biotransformation; Castration; Dehydroepiandrosterone; Estradiol; Female; Liver; Male; Pentachlorophenol; Rats; Rats, Inbred Strains; Sex Factors; Sulfotransferases; Sulfurtransferases; Testosterone | 1991 |
7-Sulfooxymethyl-12-methylbenz[a]anthracene is an electrophilic mutagen, but does not appear to play a role in carcinogenesis by 7,12-dimethylbenz[a]anthracene or 7-hydroxymethyl-12-methylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Administration, Topical; Animals; Chlorides; Cytosol; DNA; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Mutagens; Papilloma; Rats; Rats, Inbred Strains; Salmonella typhimurium; Skin Neoplasms; Sulfotransferases | 1991 |
Rat liver cytosolic hydroxysteroid sulfotransferase (sulfotransferase a) catalyzing the formation of reactive sulfate esters from carcinogenic polycyclic hydroxymethylarenes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Binding, Competitive; Biotransformation; Carcinogens; Chrysenes; Cytosol; Female; Liver; Polycyclic Compounds; Rabbits; Rats; Sex Differentiation; Sulfates; Sulfotransferases; Sulfurtransferases | 1990 |
Influence of effectors of prostaglandin metabolism on the toxicity induced by 7-hydroxymethyl-12-methylbenz(a)anthracene in cultured rat adrenal cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Animals; Arachidonic Acid; Arachidonic Acids; Benzo(a)pyrene; Bradykinin; Cells, Cultured; Dexamethasone; Drug Synergism; Hydrocortisone; Masoprocol; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats | 1990 |
Hepatic DNA and RNA adduct formation from the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene and its electrophilic sulfuric acid ester metabolite in preweanling rats and mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; Female; Liver; Male; Mice; Rats; RNA; Sulfurtransferases; Tritium | 1987 |
Selective oxidation of mitochondrial glutathione in cultured rat adrenal cells and its relation to polycyclic aromatic hydrocarbon-induced cytotoxicity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Cytosol; Digitonin; Glutathione; L-Lactate Dehydrogenase; Microscopy, Phase-Contrast; Mitochondria; Oxidation-Reduction; Polycyclic Compounds; Rats | 1989 |
Effect of 7-hydroxymethyl-12-methylbenz[a]anthracene and 1,3-bis-(2-chloroethyl)-1-nitrosourea on enzyme activities and oxidation of glutathione in cultured rat adrenal cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Glands; Animals; Carmustine; Cells, Cultured; Citrate (si)-Synthase; Electron Transport Complex IV; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Isocitrate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; NADP Transhydrogenases; Rats | 1989 |
Toxicity of 7,12-dimethylbenz[a]anthracene and 7-hydroxymethyl-12-methylbenz[a]anthracene and its prevention in cultured rat adrenal cells. Evidence for a peroxidative mechanism of action.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Antioxidants; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme System; Female; Kinetics; Rats; Rats, Inbred Strains | 1987 |
Induction of mammary cytochromes P-450: an essential first step in the metabolism of 7,12-dimethylbenz[a]anthracene by rat mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Antibodies; Cells, Cultured; Cytochrome P-450 Enzyme System; Epithelium; Female; Isoenzymes; Mammary Glands, Animal; Rats; Rats, Inbred Strains; Solubility; Water | 1987 |
The carcinogen, 7-hydroxymethyl-12-methylbenz[a]anthracene, is activated and covalently binds to DNA via a sulphate ester.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Carcinogens; DNA; Fluorescence; In Vitro Techniques; Male; Mass Spectrometry; Rats; Rats, Inbred Strains; Sulfuric Acids | 1985 |
Covalent binding of the proximate carcinogen, 7-hydroxymethyl-12-methylbenz[a]anthracene (7-HMBA) to rat liver cytosolic protein via 7-HMBA sulphate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Chemical Phenomena; Chemistry; Cytosol; In Vitro Techniques; Liver; Male; Protein Binding; Proteins; Rats; Rats, Inbred Strains | 1983 |
Formation of 7-hydroxymethyl-12-methylbenz(a)anthracene-DNA adducts from 7,12-dimethylbenz(a)anthracene in mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; DNA; Female; Mice; Mice, Inbred Strains; Skin; Tritium | 1983 |
The metabolism of 7,12-dimethylbenz[a]anthracene and 7-hydroxymethyl-12-methylbenz[a]anthracene by rat liver and adrenal homogenates and by rat adrenocortical cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Adrenal Glands; Animals; Benz(a)Anthracenes; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Liver; Rats; Rats, Inbred Strains | 1983 |
The role of secondary metabolism in the metabolic activation of 7,12-dimethylbenz[a]anthracene by rat liver microsomes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Cytochrome P-450 Enzyme System; In Vitro Techniques; Microsomes, Liver; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Biotransformation of 7, 12-dimethylbenz(a)anthracene(DMBA): on the genesis of DMBA-trans-dihydrodiols and DMBA-7- and 12-methylhydroxylated metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Carbon Disulfide; Flavonoids; Liver; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship | 1980 |
Metabolism of 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene by rat liver and microsomes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cell Nucleus; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats | 1981 |
A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[alpha]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Biotransformation; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Structure-Activity Relationship; Sulfuric Acids | 1982 |
7, 12-dimethylbenz [a] anthracene-deoxyribonucleoside adduct formation in vivo: evidence for the formation and binding of a mono-hydroxymethyl-DMBA metabolite to rat liver DNA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Deoxyribonucleosides; DNA; Female; Liver; Rats; Rats, Inbred Strains | 1982 |
Conjugation of 7-hydroxymethyl-12-methylbenz[a]anthracene (7-HMBA) with glutathione via a sulphate ester in hepatic cytosol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cytosol; Glutathione; In Vitro Techniques; Liver; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sulfates | 1982 |
7-Sulfooxymethyl-12-methylbenz[a]anthracene is an exceptionally reactive electrophilic mutagen and ultimate carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mutagens; Rats; Rats, Sprague-Dawley; Sarcoma, Experimental | 1997 |
Detection of benzylic adducts in DNA and nucleotides from 7-sulfooxymethyl-12-methylbenz[a]anthracene and related compounds by 32P-postlabeling using new TLC systems.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cattle; Chromatography, Thin Layer; Deoxyribonucleosides; DNA Adducts; DNA Damage; Phosphorus Radioisotopes | 2003 |