Compounds > 7-hydroxymethyl-12-methylbenz(a)anthracene
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7-hydroxymethyl-12-methylbenz(a)anthracene and 7-(hydroxymethyl)-12-methylbenz(a)anthracene sulfate ester

7-hydroxymethyl-12-methylbenz(a)anthracene has been researched along with 7-(hydroxymethyl)-12-methylbenz(a)anthracene sulfate ester in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liem, A; Miller, EC; Miller, JA; Surh, YJ2
Lai, CC; Miller, EC; Miller, JA; Surh, YJ1
Aizawa, T; Hakamata, Y; Ishizuka, T; Isobe, M; Watabe, T1
Ishizuka, T; Isobe, M; Ozawa, N; Watabe, T1
Flesher, JW; Horn, J; Lehner, AF1

Other Studies

6 other study(ies) available for 7-hydroxymethyl-12-methylbenz(a)anthracene and 7-(hydroxymethyl)-12-methylbenz(a)anthracene sulfate ester

ArticleYear
Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activity.
    Biochemical pharmacology, 1991, Jan-15, Volume: 41, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Biotransformation; Castration; Dehydroepiandrosterone; Estradiol; Female; Liver; Male; Pentachlorophenol; Rats; Rats, Inbred Strains; Sex Factors; Sulfotransferases; Sulfurtransferases; Testosterone

1991
7-Sulfooxymethyl-12-methylbenz[a]anthracene is an electrophilic mutagen, but does not appear to play a role in carcinogenesis by 7,12-dimethylbenz[a]anthracene or 7-hydroxymethyl-12-methylbenz[a]anthracene.
    Carcinogenesis, 1991, Volume: 12, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Administration, Topical; Animals; Chlorides; Cytosol; DNA; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Mutagens; Papilloma; Rats; Rats, Inbred Strains; Salmonella typhimurium; Skin Neoplasms; Sulfotransferases

1991
Hepatic DNA and RNA adduct formation from the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene and its electrophilic sulfuric acid ester metabolite in preweanling rats and mice.
    Biochemical and biophysical research communications, 1987, Apr-29, Volume: 144, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromatography, High Pressure Liquid; DNA; Female; Liver; Male; Mice; Rats; RNA; Sulfurtransferases; Tritium

1987
Covalent binding of the proximate carcinogen, 7-hydroxymethyl-12-methylbenz[a]anthracene (7-HMBA) to rat liver cytosolic protein via 7-HMBA sulphate.
    Biochemical pharmacology, 1983, Jul-01, Volume: 32, Issue:13

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Chemical Phenomena; Chemistry; Cytosol; In Vitro Techniques; Liver; Male; Protein Binding; Proteins; Rats; Rats, Inbred Strains

1983
A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[alpha]anthracene.
    Science (New York, N.Y.), 1982, Jan-22, Volume: 215, Issue:4531

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Biotransformation; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Structure-Activity Relationship; Sulfuric Acids

1982
7-Sulfooxymethyl-12-methylbenz[a]anthracene is an exceptionally reactive electrophilic mutagen and ultimate carcinogen.
    Biochemical and biophysical research communications, 1997, Feb-03, Volume: 231, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mutagens; Rats; Rats, Sprague-Dawley; Sarcoma, Experimental

1997