7-hydroxycoumarin glucuronide has been researched along with warfarin in 9 studies
| Studies (7-hydroxycoumarin glucuronide) | Trials (7-hydroxycoumarin glucuronide) | Recent Studies (post-2010) (7-hydroxycoumarin glucuronide) | Studies (warfarin) | Trials (warfarin) | Recent Studies (post-2010) (warfarin) |
|---|---|---|---|---|---|
| 15 | 1 | 3 | 36,573 | 2,143 | 14,728 |
| Protein | Taxonomy | 7-hydroxycoumarin glucuronide (IC50) | warfarin (IC50) |
|---|---|---|---|
| Vitamin K epoxide reductase complex subunit 1 | Homo sapiens (human) | 0.0088 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, YN; Dong, MS; Hong, SS | 1 |
| Hardt, TJ; Ritschel, WA | 1 |
| Cole, RO; Hiller, DL | 1 |
| Bogan, DP; Killard, AJ; O'Kennedy, R | 1 |
| Bogan, DP; O'Kennedy, R | 1 |
| Siegers, CP; Steffen, B; Weber, US | 1 |
| Duffy, CF; O'Kennedy, R | 1 |
| Ashton, M; Asimus, S; Hai, TN; Van Huong, N | 1 |
| de Graaf, IA; Groothuis, GM; Koenderink, JB; Russel, FG; Siissalo, S; van den Broek, PH; van den Heuvel, JJ; Wittgen, HG | 1 |
1 trial(s) available for 7-hydroxycoumarin glucuronide and warfarin
| Article | Year |
|---|---|
Artemisinin and CYP2A6 activity in healthy subjects.
Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Enzyme Induction; Humans; Male; Mixed Function Oxygenases; Nicotine; Tandem Mass Spectrometry; Umbelliferones; Vietnam | 2008 |
8 other study(ies) available for 7-hydroxycoumarin glucuronide and warfarin
| Article | Year |
|---|---|
Functional relationship between initial oxidation of 7-ethoxycoumarin and subsequent conjugation of 7-hydroxycoumarin in isolated perfused rat livers.
Topics: Animals; Coumarins; Kinetics; Liver; Male; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains; Umbelliferones | 1987 |
Dose-related pharmacokinetics of coumarin, 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide upon intraperitoneal administration of coumarin and 7-hydroxycoumarin in the rat.
Topics: Animals; Coumarins; Dose-Response Relationship, Drug; Half-Life; Injections, Intraperitoneal; Kinetics; Rats; Rats, Inbred Strains; Umbelliferones | 1983 |
Short-column gradient elution high-performance liquid chromatography for the rapid determination of 7-ethoxycoumarin metabolites in liver-slice incubates.
Topics: Animals; Chromatography, High Pressure Liquid; Coumarins; Culture Techniques; Humans; Liver; Mice; Reproducibility of Results; Umbelliferones | 1995 |
Analysis of the glucuronidation of 7-hydroxycoumarin by HPLC.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Coumarins; Glucuronosyltransferase; In Vitro Techniques; Liver; Umbelliferones | 1996 |
Simultaneous determination of coumarin, 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide in human serum and plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Coumarins; Humans; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Umbelliferones | 1996 |
Antitumor-activities of coumarin, 7-hydroxy-coumarin and its glucuronide in several human tumor cell lines.
Topics: Antineoplastic Agents; Caco-2 Cells; Carcinoma, Hepatocellular; Coumarins; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Leukemia, Lymphoid; Liver Neoplasms; Stomach Neoplasms; Tumor Cells, Cultured; Umbelliferones | 1998 |
Determination of 7-hydroxycoumarin and its glucuronide and sulphate conjugates in liver slice incubates by capillary zone electrophoresis.
Topics: Animals; Antineoplastic Agents; Coumarins; Electrophoresis, Capillary; Liver; Mice; Mice, Inbred BALB C; Umbelliferones | 1998 |
Transport of the coumarin metabolite 7-hydroxycoumarin glucuronide is mediated via multidrug resistance-associated proteins 3 and 4.
Topics: Biological Transport, Active; Coumarins; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Umbelliferones | 2012 |