Page last updated: 2024-09-03

7-hydroxycoumarin glucuronide and coumarin

7-hydroxycoumarin glucuronide has been researched along with coumarin in 7 studies

*coumarin: effective in reducing edema following crush & thermal injury; structure in Merck Index, 9th ed, #2547; Coumarin itself occurs in the Tonka bean [MeSH]

*coumarin: effective in reducing edema following crush & thermal injury; structure in Merck Index, 9th ed, #2547; Coumarin itself occurs in the Tonka bean [MeSH]

Compound Research Comparison

Studies
(7-hydroxycoumarin glucuronide)
Trials
(7-hydroxycoumarin glucuronide)
Recent Studies (post-2010)
(7-hydroxycoumarin glucuronide)
Studies
(coumarin)
Trials
(coumarin)
Recent Studies (post-2010) (coumarin)
15133,436621,302

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hardt, TJ; Ritschel, WA1
Bogan, DP; Killard, AJ; O'Kennedy, R1
Bogan, DP; O'Kennedy, R1
Siegers, CP; Steffen, B; Weber, US1
Duffy, CF; O'Kennedy, R1
Ashton, M; Asimus, S; Hai, TN; Van Huong, N1
de Graaf, IA; Groothuis, GM; Koenderink, JB; Russel, FG; Siissalo, S; van den Broek, PH; van den Heuvel, JJ; Wittgen, HG1

Trials

1 trial(s) available for 7-hydroxycoumarin glucuronide and coumarin

ArticleYear
Artemisinin and CYP2A6 activity in healthy subjects.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

    Topics: Adult; Antimalarials; Area Under Curve; Artemisinins; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Enzyme Induction; Humans; Male; Mixed Function Oxygenases; Nicotine; Tandem Mass Spectrometry; Umbelliferones; Vietnam

2008

Other Studies

6 other study(ies) available for 7-hydroxycoumarin glucuronide and coumarin

ArticleYear
Dose-related pharmacokinetics of coumarin, 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide upon intraperitoneal administration of coumarin and 7-hydroxycoumarin in the rat.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:10

    Topics: Animals; Coumarins; Dose-Response Relationship, Drug; Half-Life; Injections, Intraperitoneal; Kinetics; Rats; Rats, Inbred Strains; Umbelliferones

1983
Analysis of the glucuronidation of 7-hydroxycoumarin by HPLC.
    Journal of pharmaceutical and biomedical analysis, 1996, Volume: 14, Issue:11

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Coumarins; Glucuronosyltransferase; In Vitro Techniques; Liver; Umbelliferones

1996
Simultaneous determination of coumarin, 7-hydroxycoumarin and 7-hydroxycoumarin glucuronide in human serum and plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1996, Nov-15, Volume: 686, Issue:2

    Topics: Chromatography, High Pressure Liquid; Coumarins; Humans; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Umbelliferones

1996
Antitumor-activities of coumarin, 7-hydroxy-coumarin and its glucuronide in several human tumor cell lines.
    Research communications in molecular pathology and pharmacology, 1998, Volume: 99, Issue:2

    Topics: Antineoplastic Agents; Caco-2 Cells; Carcinoma, Hepatocellular; Coumarins; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Leukemia, Lymphoid; Liver Neoplasms; Stomach Neoplasms; Tumor Cells, Cultured; Umbelliferones

1998
Determination of 7-hydroxycoumarin and its glucuronide and sulphate conjugates in liver slice incubates by capillary zone electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Coumarins; Electrophoresis, Capillary; Liver; Mice; Mice, Inbred BALB C; Umbelliferones

1998
Transport of the coumarin metabolite 7-hydroxycoumarin glucuronide is mediated via multidrug resistance-associated proteins 3 and 4.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:6

    Topics: Biological Transport, Active; Coumarins; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Umbelliferones

2012