7-hydroxychlorpromazine has been researched along with chlorpromazine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Pajeva, I; Wiese, M | 1 |
| Dalvie, D; Loi, CM; Smith, DA | 1 |
| Chibale, K; Kigondu, EM; Warner, DF; Wasuna, A | 1 |
| Chetty, M; Miller, R | 1 |
| Braff, L; Craig, JC; Fischer, A; Glick, ID; Gruenke, LD; Hitzemann, BA; Holaday, JW; Klein, FD; Loh, HH; Nguyen, TL | 1 |
| Hubbard, JW; Korchinski, ED; Midha, KK; Yeung, PK | 1 |
| Chakraborty, BS; Cooper, JK; Gurnsey, T; Hawes, EM; Hubbard, JW; McKay, G; Midha, KK; Yeung, PK | 1 |
| Hubbard, JW; McKay, G; Midha, KK; Ramshaw, IA; Yeung, PK | 1 |
| Alfredsson, G; Bjerkenstedt, L; Edman, G; Härnryd, C; Oxenstierna, G; Sedvall, G; Wiesel, FA | 1 |
| Kagan, VE; Kovaleva, ES; Muranov, KO; Prilipko, LL | 1 |
| Alfredsson, G; Wode-Helgodt, B | 1 |
| Alfredsson, G; Lindberg, M; Sedvall, G | 1 |
| FISHMAN, V; GOLDENBERG, H | 2 |
| BERRY, K; CULLING, CF; HANSEN, S; PERRY, TL | 1 |
| GUDZINOWICZ, BJ; MARTIN, HF; PRICE, S | 1 |
| Fu, T; Guo, Y; Huang, S; Wang, X; Yao, B; Zhang, Y | 1 |
1 review(s) available for 7-hydroxychlorpromazine and chlorpromazine
| Article | Year |
|---|---|
Pharmacologically active metabolites, combination screening and target identification-driven drug repositioning in antituberculosis drug discovery.
Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Drug Discovery; Fusidic Acid; Humans; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis | 2014 |
2 trial(s) available for 7-hydroxychlorpromazine and chlorpromazine
| Article | Year |
|---|---|
Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Patient Compliance; Prolactin; Schizophrenia; Sulpiride | 1984 |
Concentrations of chlorpromazine and two of its active metabolites in plasma and cerebrospinal fluid of psychotic patients treated with fixed drug doses.
Topics: Adult; Aging; Chlorpromazine; Female; Humans; Male; Middle Aged; Psychotic Disorders; Sex Factors; Time Factors | 1981 |
14 other study(ies) available for 7-hydroxychlorpromazine and chlorpromazine
| Article | Year |
|---|---|
Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.
Topics: Antineoplastic Agents; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Conformation; Phenothiazines; Thioxanthenes; Tumor Cells, Cultured | 1998 |
Which metabolites circulate?
Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations | 2013 |
Effect of storage on the plasma concentration of chlorpromazine and six of its metabolites.
Topics: Chlorpromazine; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Humans; Schizophrenia | 1991 |
Determination of chlorpromazine and its major metabolites by gas chromatography/mass spectrometry: application to biological fluids.
Topics: Biotransformation; Body Fluids; Chlorpromazine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Humans; Schizophrenia | 1985 |
Radioimmunoassay for the N-oxide metabolite of chlorpromazine in human plasma and its application to a pharmacokinetic study in healthy humans.
Topics: Adult; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Half-Life; Humans; Male; Plasma; Radioimmunoassay; Spectrophotometry, Ultraviolet | 1987 |
Therapeutic monitoring of chlorpromazine. IV: Comparison of a new high-performance liquid chromatographic method with radioimmunoassays for parent drug and some of its major metabolites.
Topics: Chlorpromazine; Chromatography, High Pressure Liquid; Male; Monitoring, Physiologic; Radioimmunoassay; Regression Analysis | 1987 |
A comparison of two radioimmunoassays for 7-hydroxychlorpromazine: rabbit polyclonal antibodies vs. mouse monoclonal antibodies.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Chlorpromazine; Cross Reactions; Female; Humans; Male; Mice; Mice, Inbred BALB C; Rabbits; Radioimmunoassay | 1985 |
[Effect of antioxidants on the release of 3H-serotonin by rat brain synaptosomes].
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Cerebral Cortex; Chlorpromazine; In Vitro Techniques; Picolines; Rats; Serotonin; Synaptosomes; Tritium; Vitamin E | 1983 |
The presence of 7-hydroxychlorpromazine in CSF of chloropromazine-treated patients.
Topics: Adult; Chlorpromazine; Female; Humans; Male | 1982 |
Metabolism of chlorpromazine. IV. Identification of 7-hydroxychlorpromazine and its sulfoxide and desmethyl derivatives.
Topics: Chlorpromazine; Phenols; Safrole; Sulfoxides | 1963 |
7-HYDROXYCHLORPROMAZINE: POTENTIAL TOXIC DRUG METABOLITE IN PSYCHIATRIC PATIENTS.
Topics: Body Fluids; Chlorpromazine; Humans; Lens, Crystalline; Liver; Melanins; Mental Disorders; Metabolism; Pigmentation; Pigmentation Disorders; Skin; Toxicology; Urine | 1964 |
7-HYDROXYCHLORPROMAZINE IN THE URINES OF SCHIZOPHRENICS RECEIVING CHLROPROMAZINE.
Topics: Antipsychotic Agents; Chlorpromazine; Chromatography; Drug Therapy; Humans; Metabolism; Phenothiazines; Schizophrenia; Spectrophotometry; Urine | 1964 |
(COMMENTS ON "7-HYDROXYCHLORPROMAZINE IN THE URINES OF SCHIZOPHRENICS RECEIVING CHLORPROMAZINE".)
Topics: Chlorpromazine; Chromatography; Humans; Metabolism; Schizophrenia; Urine | 1965 |
Establishment of LC-MS/MS method for quantifying chlorpromazine metabolites with application to its metabolism in liver and placenta microsomes.
Topics: Animals; Chlorpromazine; Chromatography, Liquid; Humans; Liver; Microsomes, Liver; Rats; Tandem Mass Spectrometry | 2023 |