7-hydroxyamoxapine has been researched along with amoxapine in 9 studies
| Studies (7-hydroxyamoxapine) | Trials (7-hydroxyamoxapine) | Recent Studies (post-2010) (7-hydroxyamoxapine) | Studies (amoxapine) | Trials (amoxapine) | Recent Studies (post-2010) (amoxapine) |
|---|---|---|---|---|---|
| 9 | 1 | 2 | 392 | 50 | 52 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, K; Kobayashi, A; Nakazawa, K | 1 |
| Calvo, B; Domínguez-Gil, A; García, MJ; Mariño, EL; Pedraz, JL | 1 |
| Cooper, TB; Suckow, RF | 1 |
| Calvo, MB; Domínguez-Gil, A; García, MJ; Ledesma, A; Pedraz, JL; Prieto Aguirre, F | 1 |
| Kobayashi, A; Nakazawa, K; Sugita, S | 1 |
| Johnson, SM; Khalil, SK; Nygard, G | 1 |
| Hsia, D; Hubbard, JW; McKay, G; Midha, KK; Rawson, MJ | 1 |
| Wo, SK; Wong, YC; Zuo, Z | 1 |
| Ahmad, S; Kong, R; Liu, T; Phan, AT; Scott, JE; Williams, AL; Wong, ST; Yeh, LA; Zhao, H; Zhu, X | 1 |
1 trial(s) available for 7-hydroxyamoxapine and amoxapine
| Article | Year |
|---|---|
The role of metabolites in a bioequivalence study II: amoxapine, 7-hydroxyamoxapine, and 8-hydroxyamoxapine.
Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Amoxapine; Animals; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Middle Aged; Time Factors | 1999 |
8 other study(ies) available for 7-hydroxyamoxapine and amoxapine
| Article | Year |
|---|---|
In rat brain amoxapine enhances dopamine metabolism: pharmacokinetic variations of the effect.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amoxapine; Animals; Brain; Corpus Striatum; Dopamine; Drug Synergism; Frontal Lobe; Genetic Variation; Homovanillic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains | 1992 |
Pharmacokinetics of amoxapine and its active metabolites.
Topics: Adult; Amoxapine; Chromatography, Gas; Dibenzoxazepines; Female; Half-Life; Humans; Kinetics; Male; Time Factors | 1985 |
Determination of amoxapine and metabolites in plasma by liquid chromatography with electrochemical detection.
Topics: Amoxapine; Chromatography, Liquid; Dibenzoxazepines; Electrochemistry; Humans | 1985 |
[Relation of blood levels of amoxapine and its active metabolites to its pharmacologic response and toxicity].
Topics: Adolescent; Adult; Aged; Amoxapine; Depressive Disorder; Dibenzoxazepines; Half-Life; Humans; Kinetics; Middle Aged | 1985 |
Determination of amoxapine and its metabolites in human serum by high-performance liquid chromatography.
Topics: Amoxapine; Chromatography, High Pressure Liquid; Dibenzoxazepines; Humans | 1985 |
Isocratic liquid chromatographic method for the determination of amoxapine and its metabolites.
Topics: Amoxapine; Chromatography, Liquid; Dibenzoxazepines; Humans; Solutions; Spectrophotometry, Ultraviolet | 1984 |
Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS.
Topics: Administration, Oral; Amoxapine; Animals; Brain; Chromatography, Liquid; Hydroxylation; Loxapine; Male; Methanol; Perchlorates; Rats; Rats, Wistar; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |
Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity.
Topics: Amoxapine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glycoproteins; Irinotecan; Mice; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Protective Agents; Protein Binding; Xenograft Model Antitumor Assays | 2014 |