Compounds > 7-hydroxy-6-4--dimethoxyisoflavone

7-hydroxy-6-4--dimethoxyisoflavone and psi-baptigenin

7-hydroxy-6-4--dimethoxyisoflavone has been researched along with psi-baptigenin* in 2 studies

Other Studies

2 other study(ies) available for 7-hydroxy-6-4--dimethoxyisoflavone and psi-baptigenin

Article	Year
LC-ESI-MS characterisation of phytoalexins induced in chickpea and pea tissues in response to a biotic elicitor of Hypnea musciformis (red algae). Natural product research, 2011, Volume: 25, Issue:14 A simple extraction procedure and HPLC method was developed to analyse the major and minor components of induced phytoalexins of elicited tissues (seeds) of chickpeas (Cicer arietinum L.) and peas (Pisum sativum L.) treated with a biotic elicitor (k-carrageenan) of Hypnea musciformis (red algae) from the Karachi coast. The level and timing of the induced phytoalexin production were estimated on the basis of various elicitor dilutions and as a function of time; the results are presented and discussed. A LC-ESI-MS/MS technique has been employed for the detection and characterisation of the induced phytochemical components (flavonoids and their glyco-conjugates). Nine flavonoids were identified from chickpeas: naringin, naringin malonate, liquiritigenin, naringenin, biochanin A, daidzein, formononetin, maackiain and medicarpin, while five flavonoids were identified from peas: afrormosin, anhydropisatin, pisatin, pseudobaptigenin and maackiain. These compounds play a vital role as phytoalexins because of their antimicrobial activity. Topics: Carrageenan; Chromatography, High Pressure Liquid; Cicer; Flavanones; Flavonoids; Genistein; Isoflavones; Phytoalexins; Pisum sativum; Pterocarpans; Rhodophyta; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization	2011
Antigiardial activity of isoflavones from Dalbergia frutescens bark. Journal of natural products, 2000, Volume: 63, Issue:10 Several isoflavones [formononetin (1), castanin (5), odoratin (6), glycitein (7), pseudobaptogenin (8), fujikinetin (9), and cuneatin (10)] were isolated from Dalbergia frutescens, and their antiprotozoal activities were determined against Giardia intestinalis. Among these compounds, formononetin (1) was the most potent antigiardial agent, with an IC(50) value of 30 ng/mL (approximately 0.1 microM), as compared to the value for metronidazole, the current drug of choice, of 100 ng/mL (approximately 0.6 microM). Three isoflavones closely related to formononetin [daidzein (2), biochanin A (3) and genistein (4)] were also evaluated, but they were at least 100 times less active than 1. Formononetin (1) may thus be an interesting lead for development of new antigiardial agents or as a probe for a new mechanistic target. Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drugs, Chinese Herbal; Fabaceae; Female; Giardia lamblia; Isoflavones; Magnetic Resonance Spectroscopy; Mice; Plants, Medicinal	2000

Article

Year

LC-ESI-MS characterisation of phytoalexins induced in chickpea and pea tissues in response to a biotic elicitor of Hypnea musciformis (red algae).

Natural product research, 2011, Volume: 25, Issue:14

A simple extraction procedure and HPLC method was developed to analyse the major and minor components of induced phytoalexins of elicited tissues (seeds) of chickpeas (Cicer arietinum L.) and peas (Pisum sativum L.) treated with a biotic elicitor (k-carrageenan) of Hypnea musciformis (red algae) from the Karachi coast. The level and timing of the induced phytoalexin production were estimated on the basis of various elicitor dilutions and as a function of time; the results are presented and discussed. A LC-ESI-MS/MS technique has been employed for the detection and characterisation of the induced phytochemical components (flavonoids and their glyco-conjugates). Nine flavonoids were identified from chickpeas: naringin, naringin malonate, liquiritigenin, naringenin, biochanin A, daidzein, formononetin, maackiain and medicarpin, while five flavonoids were identified from peas: afrormosin, anhydropisatin, pisatin, pseudobaptigenin and maackiain. These compounds play a vital role as phytoalexins because of their antimicrobial activity.

Topics: Carrageenan; Chromatography, High Pressure Liquid; Cicer; Flavanones; Flavonoids; Genistein; Isoflavones; Phytoalexins; Pisum sativum; Pterocarpans; Rhodophyta; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization

2011

Antigiardial activity of isoflavones from Dalbergia frutescens bark.

Journal of natural products, 2000, Volume: 63, Issue:10

Several isoflavones [formononetin (1), castanin (5), odoratin (6), glycitein (7), pseudobaptogenin (8), fujikinetin (9), and cuneatin (10)] were isolated from Dalbergia frutescens, and their antiprotozoal activities were determined against Giardia intestinalis. Among these compounds, formononetin (1) was the most potent antigiardial agent, with an IC(50) value of 30 ng/mL (approximately 0.1 microM), as compared to the value for metronidazole, the current drug of choice, of 100 ng/mL (approximately 0.6 microM). Three isoflavones closely related to formononetin [daidzein (2), biochanin A (3) and genistein (4)] were also evaluated, but they were at least 100 times less active than 1. Formononetin (1) may thus be an interesting lead for development of new antigiardial agents or as a probe for a new mechanistic target.

Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drugs, Chinese Herbal; Fabaceae; Female; Giardia lamblia; Isoflavones; Magnetic Resonance Spectroscopy; Mice; Plants, Medicinal

2000