7-hydroxy-6-4--dimethoxyisoflavone has been researched along with lupeol* in 1 studies
1 other study(ies) available for 7-hydroxy-6-4--dimethoxyisoflavone and lupeol
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Chemical constituents of the bark of Dipteryx alata vogel, an active species against Bothrops jararacussu venom.
The effect of four sub-extracts prepared from the lyophilized hydroalcoholic bark of Dipteryx alata (Leguminosae-Papilionoideae) dissolved in a methanol-water (80:20) mixture through a liquid-liquid partition procedure has been investigated against the neuromuscular blockade of the venom of the snake Bothrops jararacussu. The active CH₂Cl₂ sub-extract has been extensively analyzed for its chemical constituents, resulting in the isolation of four lupane-type triterpenoids: lupeol, lupenone, 28-hydroxylup-20(29)-en-3-one, betulin, nine isoflavonoids: 8-O-methylretusin, 7-hydroxy-5,6,4'-trimethoxyisoflavone, afrormosin, 7-hydroxy-8,3',4'-trimethoxyisoflavone, 7,3'-dihydroxy-8,4'-dimethoxyisoflavone, odoratin, 7,8,3'-trihydroxy-4'-methoxyisoflavone, 7,8,3'-trihydroxy-6,4'-dimethoxyisoflavone, dipteryxin, one chalcone: isoliquiritigenin, one aurone: sulfuretin and three phenolic compounds: vanillic acid, vanillin, and protocatechuic acid. Their chemical structures were elucidated on the basis of spectroscopic analysis, including HRMS, 1D- and 2D-NMR techniques. Topics: Animals; Bothrops; Crotalid Venoms; Diaphragm; Dipteryx; In Vitro Techniques; Isoflavones; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Structure; Neuromuscular Blockade; Pentacyclic Triterpenes; Phrenic Nerve; Plant Bark; Plant Extracts; Triterpenes | 2010 |