Page last updated: 2024-09-05

7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid and dinoprostone

7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid has been researched along with dinoprostone in 13 studies

Compound Research Comparison

Studies
(7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid)
Trials
(7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid)
Recent Studies (post-2010)
(7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
39151429,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomy7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (38.46)18.2507
2000's6 (46.15)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mayatepek, E; Nützenadel, W; Seyberth, HW1
Schweer, H; Seyberth, HW; Watzer, B1
Hoffmann, GF; Linderkamp, O; Mayatepek, E; Meyburg, J; Seyberth, HW1
Frölich, JC; Stichtenoth, DO; Wagner, B1
Girschick, HJ; Huppertz, HI; Seyberth, HW1
Bernhard, M; Hoch, B1
Byrne, LM; Csiki, I; Johnson, DH; Morrow, JD; Murphey, LJ; Oates, JA; Sanchez, SC; Williams, MK1
Boyle, JO; Dannenberg, AJ; Duffield-Lillico, AJ; Gross, ND; Morrow, JD; Moskowitz, CS; Subbaramaiah, K; Williams, MK1
Carbone, DP; Csiki, I; Dang, T; Johnson, DH; Morrow, JD; Oates, J; Sandler, A; Shyr, Y; Williams, MK1
Frölich, JC; Gutzki, FM; Marhauer, V; Stichtenoth, DO; Tsikas, D1
Cohen, DA; Haack, M; Lee, E; Mullington, JM1
Cai, Q; Chen, Z; Milne, G; Ness, RM; Shrubsole, MJ; Smalley, WE; Wen, W; Zheng, W1
Fu, WZ; He, JW; Zhang, CQ; Zhang, Z; Zhang, ZL1

Trials

5 trial(s) available for 7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid and dinoprostone

ArticleYear
Effects of meloxicam and indomethacin on cyclooxygenase pathways in healthy volunteers.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1997, Volume: 45, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Indomethacin; Meloxicam; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Therapeutic Equivalency; Thiazines; Thiazoles; Thromboxane B2

1997
Central apnoea and endogenous prostaglandins in neonates.
    Acta paediatrica (Oslo, Norway : 1992), 2000, Volume: 89, Issue:11

    Topics: Apnea; Bradycardia; Chromatography, Gas; Data Interpretation, Statistical; Dinoprostone; Electrocardiography; Female; Heart Rate; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Mass Spectrometry; Oximetry; Oxygen; Plethysmography; Polysomnography; Prostaglandins; Time Factors

2000
Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase II trial of celecoxib and docetaxel.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inducing Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Celecoxib; Cohort Studies; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Docetaxel; Endostatins; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Membrane Proteins; Middle Aged; Nausea; Neoplasm Recurrence, Local; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Sulfonamides; Survival Analysis; Taxoids; Treatment Outcome; Vascular Endothelial Growth Factor A; Vomiting

2005
Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Body Weight; Celecoxib; Creatinine; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Diuretics; Female; Furosemide; Humans; Indomethacin; Kidney; Potassium; Prostaglandins; Pyrazoles; Renin; Sodium; Sulfonamides; Thromboxane B2

2005
Activation of the prostaglandin system in response to sleep loss in healthy humans: potential mediator of increased spontaneous pain.
    Pain, 2009, Volume: 145, Issue:1-2

    Topics: Adult; Affect; Dinoprostone; Female; Humans; Linear Models; Male; Middle Aged; Pain Measurement; Pain Threshold; Polysomnography; Prostaglandins; Sleep; Sleep Deprivation; Wakefulness; Young Adult

2009

Other Studies

8 other study(ies) available for 7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid and dinoprostone

ArticleYear
Effects of indomethacin in congenital chloride diarrhea.
    Journal of pediatric gastroenterology and nutrition, 1992, Volume: 14, Issue:3

    Topics: 18-Hydroxycorticosterone; Aldosterone; Chlorine; Diarrhea; Dinoprost; Dinoprostone; Humans; Indomethacin; Infant; Male; Potassium Chloride; Prostaglandins; Renin; Sodium Chloride; Water-Electrolyte Balance

1992
Determination of seven prostanoids in 1 ml of urine by gas chromatography-negative ion chemical ionization triple stage quadrupole mass spectrometry.
    Journal of chromatography, 1994, Feb-11, Volume: 652, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Chromatography, Thin Layer; Dinoprostone; Gas Chromatography-Mass Spectrometry; Humans; Prostaglandins; Thromboxane B2

1994
Severe hyperchloriduria-hyperkaliuria: a new congenital renal tubular abnormality?
    The Journal of pediatrics, 1996, Volume: 128, Issue:3

    Topics: Bartter Syndrome; Calcium; Chlorides; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; Indomethacin; Infant; Potassium; Prostaglandins; Renal Tubular Transport, Inborn Errors; Syndrome

1996
Treatment of childhood hypophosphatasia with nonsteroidal antiinflammatory drugs.
    Bone, 1999, Volume: 25, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Dinoprostone; Follow-Up Studies; Gait; Humans; Hypophosphatasia; Infant; Kidney; Leg; Male; Pain; Prostaglandins

1999
Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer.
    Analytical biochemistry, 2004, Nov-15, Volume: 334, Issue:2

    Topics: Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Chromatography, Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Health; Humans; Lung Neoplasms; Membrane Proteins; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2004
Levels of prostaglandin E metabolite, the major urinary metabolite of prostaglandin E2, are increased in smokers.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Dinoprostone; Female; Head and Neck Neoplasms; Humans; Logistic Models; Male; Mass Spectrometry; Middle Aged; Prostaglandins; Prostaglandins E; Smoking

2005
Urinary prostaglandin E2 metabolite and risk for colorectal adenoma.
    Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:2

    Topics: Adenoma; Adult; Aged; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Female; Humans; Male; Middle Aged; Prognosis; Prostaglandins

2012
Mutations in the SLCO2A1 gene and primary hypertrophic osteoarthropathy: a clinical and biochemical characterization.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:5

    Topics: Adolescent; Adult; Age Factors; Amino Acid Sequence; China; Cohort Studies; Dinoprostone; DNA Mutational Analysis; Family Health; Female; Genetic Association Studies; Humans; Male; Molecular Sequence Data; Mutation; Organic Anion Transporters; Osteoarthropathy, Primary Hypertrophic; Pedigree; Prostaglandins; Protein Structure, Secondary; Sequence Alignment; Young Adult

2013