Page last updated: 2024-09-03

7-ethylcamptothecin and irinotecan

7-ethylcamptothecin has been researched along with irinotecan in 3 studies

Compound Research Comparison

Studies
(7-ethylcamptothecin)
Trials
(7-ethylcamptothecin)
Recent Studies (post-2010)
(7-ethylcamptothecin)
Studies
(irinotecan)
Trials
(irinotecan)
Recent Studies (post-2010) (irinotecan)
8018,0021,8853,752

Protein Interaction Comparison

ProteinTaxonomy7-ethylcamptothecin (IC50)irinotecan (IC50)
Solute carrier family 22 member 2Homo sapiens (human)2.7
Interstitial collagenaseHomo sapiens (human)6.06
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.556
Alpha-2C adrenergic receptorHomo sapiens (human)3.171
AcetylcholinesteraseHomo sapiens (human)1.827
Multidrug and toxin extrusion protein 2Homo sapiens (human)7.9
Multidrug and toxin extrusion protein 1Homo sapiens (human)4.7667

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, H; Kunimoto, T; Miyasaka, T; Mutai, M; Nitta, K; Sawada, S; Takeuchi, M; Tanaka, T; Uehara, N; Yokokura, T1
Fujita, Y; Oyama, H; Sawada, S; Tsuru, D; Yaegashi, T; Yoshimoto, T1
Bordovská, S; Meloun, M; Vrána, A1

Other Studies

3 other study(ies) available for 7-ethylcamptothecin and irinotecan

ArticleYear
[Antitumor activity of new derivatives of camptothecin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Camptothecin; Doxorubicin; Irinotecan; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasms, Experimental

1987
Partial purification and characterization of an esterase acting on the anticancer pro-drugs, 7-ethylcamptothecin derivatives.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chromatography, High Pressure Liquid; Esterases; Irinotecan; Liver; Male; Pancreas; Prodrugs; Rats; Rats, Wistar

1995
The thermodynamic dissociation constants of the anticancer drugs camptothecine, 7-ethyl-10-hydroxycamptothecine, 10-hydroxycamptothecine and 7-ethylcamptothecine by the least-squares nonlinear regression of multiwavelength spectrophotometric pH-titration
    Analytica chimica acta, 2007, Feb-19, Volume: 584, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Hydrogen-Ion Concentration; Irinotecan; Least-Squares Analysis; Spectrophotometry, Ultraviolet; Thermodynamics; Titrimetry

2007