7-ethylcamptothecin has been researched along with camptothecin in 7 studies
| Studies (7-ethylcamptothecin) | Trials (7-ethylcamptothecin) | Recent Studies (post-2010) (7-ethylcamptothecin) | Studies (camptothecin) | Trials (camptothecin) | Recent Studies (post-2010) (camptothecin) |
|---|---|---|---|---|---|
| 8 | 0 | 1 | 13,002 | 2,229 | 5,391 |
| Protein | Taxonomy | 7-ethylcamptothecin (IC50) | camptothecin (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.05 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 7.4 | |
| DNA topoisomerase 1 | Homo sapiens (human) | 1.9799 | |
| Somatostatin receptor type 1 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 2 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 4 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 3 | Homo sapiens (human) | 0.0022 | |
| Somatostatin receptor type 5 | Homo sapiens (human) | 0.0022 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.97 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.05 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 9 | Homo sapiens (human) | 0.05 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.05 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, H; Kunimoto, T; Miyasaka, T; Mutai, M; Nitta, K; Sawada, S; Takeuchi, M; Tanaka, T; Uehara, N; Yokokura, T | 2 |
| Fukada, M; Furuta, T; Kaneda, N; Miyasaka, T; Nagata, H; Notake, K; Sawada, S; Yokokura, T | 1 |
| Fujita, Y; Oyama, H; Sawada, S; Tsuru, D; Yaegashi, T; Yoshimoto, T | 1 |
| Furuta, T; Miyasaka, T; Sawada, S; Yaegashi, T; Yokokura, T | 1 |
| Bordovská, S; Meloun, M; Vrána, A | 1 |
| Alferiev, IS; Brodeur, GM; Chorny, M; Fishbein, I; Guan, P; Guerrero, DT; Kolla, V; Nguyen, F; Pressly, BB; Soberman, D | 1 |
7 other study(ies) available for 7-ethylcamptothecin and camptothecin
| Article | Year |
|---|---|
[Antitumor activity of new derivatives of camptothecin].
Topics: Animals; Antineoplastic Agents; Camptothecin; Doxorubicin; Irinotecan; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasms, Experimental | 1987 |
Antitumor activity of a new camptothecin derivative, SN-22, against various murine tumors.
Topics: Animals; Antineoplastic Agents; Camptothecin; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred Strains; Neoplasms, Experimental | 1987 |
Action of 7-ethylcamptothecin on tumor cells and its disposition in mice.
Topics: Animals; Camptothecin; Cell Cycle; Cell Division; Chromatography, High Pressure Liquid; Female; Flow Cytometry; Kinetics; Leukemia L1210; Mice; Tissue Distribution | 1987 |
Partial purification and characterization of an esterase acting on the anticancer pro-drugs, 7-ethylcamptothecin derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chromatography, High Pressure Liquid; Esterases; Irinotecan; Liver; Male; Pancreas; Prodrugs; Rats; Rats, Wistar | 1995 |
Chemical modification of an antitumor alkaloid, 20(S)-camptothecin: E-lactone ring-modified water-soluble derivatives of 7-ethylcamptothecin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Lactones; Leukemia L1210; Mice; Solubility; Water | 1993 |
The thermodynamic dissociation constants of the anticancer drugs camptothecine, 7-ethyl-10-hydroxycamptothecine, 10-hydroxycamptothecine and 7-ethylcamptothecine by the least-squares nonlinear regression of multiwavelength spectrophotometric pH-titration
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Hydrogen-Ion Concentration; Irinotecan; Least-Squares Analysis; Spectrophotometry, Ultraviolet; Thermodynamics; Titrimetry | 2007 |
Nanocarrier-Based Delivery of SN22 as a Tocopheryl Oxamate Prodrug Achieves Rapid Tumor Regression and Extends Survival in High-Risk Neuroblastoma Models.
Topics: Camptothecin; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Humans; Nanoparticles; Neuroblastoma; Prodrugs; Risk Factors; Survival Analysis; Tocopherols; Xenograft Model Antitumor Assays | 2022 |