Page last updated: 2024-09-05

7-epipaclitaxel and paclitaxel

7-epipaclitaxel has been researched along with paclitaxel in 6 studies

Compound Research Comparison

Studies
(7-epipaclitaxel)
Trials
(7-epipaclitaxel)
Recent Studies (post-2010)
(7-epipaclitaxel)
Studies
(paclitaxel)
Trials
(paclitaxel)
Recent Studies (post-2010) (paclitaxel)
80331,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomy7-epipaclitaxel (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Kobayashi, J; Shigemori, H1
Awale, S; Dang, PH; Duong, TTT; Nguyen, HX; Nguyen, MTT; Nguyen, NT; Nguyen, PT; Phan, NHT; Tran, TKT; Vu, TKT; Vuong, HC1
Hao, X; Liu, Y; Ma, X; Zhou, M; Zhu, X1
Cenacchi, V; Fraier, D; Frigerio, E1
Ai, CZ; Ge, GB; He, YQ; Liu, XB; Wang, ZT; Yang, L; Zhang, R; Zhang, YY1
Gao, JM; Li, J; Shi, YQ; Zhang, CY; Zhang, QM1

Reviews

1 review(s) available for 7-epipaclitaxel and paclitaxel

ArticleYear
Biological activity and chemistry of taxoids from the Japanese yew, Taxus cuspidata.
    Journal of natural products, 2004, Volume: 67, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Molecular Structure; Paclitaxel; Plants, Medicinal; Stereoisomerism; Structure-Activity Relationship; Taxoids; Taxus

2004

Other Studies

5 other study(ies) available for 7-epipaclitaxel and paclitaxel

ArticleYear
α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: alpha-Glucosidases; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Diterpenes; Glycoside Hydrolase Inhibitors; Humans; Molecular Structure; Paclitaxel; Plant Bark; Taxoids; Taxus

2017
An effective method to produce 7-epitaxol from taxol in HCO
    Bioorganic & medicinal chemistry letters, 2020, 08-01, Volume: 30, Issue:15

    Topics: Acetonitriles; Antifungal Agents; Microbial Sensitivity Tests; Molecular Conformation; Paclitaxel; Saccharomyces cerevisiae; Sodium Bicarbonate

2020
Determination of a new polymer-bound paclitaxel derivative (PNU 166945), free paclitaxel and 7-epipaclitaxel in dog plasma and urine by reversed-phase high-performance liquid chromatography with UV detection.
    Journal of chromatography. A, 1998, Feb-27, Volume: 797, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Dogs; Drug Stability; Hydrolysis; Kinetics; Paclitaxel; Polymers; Spectrophotometry, Ultraviolet; Taxoids

1998
Stereochemical differentiation of C-7 hydroxyltaxane isomers by electrospray ionization mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2009, Volume: 23, Issue:3

    Topics: Chromatography, Liquid; Models, Molecular; Molecular Structure; Paclitaxel; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Taxoids

2009
[The impurity profiling of paclitaxel and its injection by UPLC-MS/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:6

    Topics: Alkaloids; China; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Contamination; Injections; Paclitaxel; Tandem Mass Spectrometry; Taxoids

2016