7-chlorokynurenic acid and strychnine

7-chlorokynurenic acid has been researched along with strychnine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's21 (77.78)18.2507
2000's5 (18.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bostock, E; Sorrels, TL1
Inoue, K; Katayama, K; Morimoto, K; Namba, T; Otsuki, S; Yamada, N1
Peeters, BW; Vanderheyden, PM1
Bradford, HF; Croucher, MJ2
Kloog, Y; Lamdani-Itkin, H; Sokolovsky, M1
Oles, RJ; Singh, L; Tricklebank, MD1
Craig, CG; White, TD1
Chiamulera, C; Costa, S; Reggiani, A1
Britt, M; Klika, AB; Meiners, BA; Powel, RJ; Pullan, LM; Salama, AI; Stumpo, RJ1
Brugger, F; Fagg, GE; Nassenstein-Elton, D; Olpe, HR; Pozza, MF; Wicki, U1
Harris, KM; Miller, RJ1
Bubser, M; Kretschmer, BD; Schmidt, WJ1
Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M1
Berger, P; Farrel, K; Sharp, F; Skolnick, P1
Boje, KM; Skolnick, P; Wong, G1
Peterson, SL1
Biella, G; Lacerenza, M; Marchettini, P; Sotgiu, ML1
Bland, LR; Layer, RT; Skolnick, P1
Koch, M; Kretschmer, BD1
Kawabe, A; Maruoka, Y; Nakamura, M; Ohno, Y; Ohtani, K; Sakamoto, H; Tamamura, C; Tanaka, H; Yasuda, H1
Cugola, A; Donati, D; Micheli, F; Missio, A; Pecunioso, A; Reggiani, A; Tarzia, G1
Devau, G1
Johnson, SW; Zheng, F1
Barth, A; Barth, L; Newell, DW; Nguyen, LB1
DiGregorio, DA; Nielsen, TA; Sargent, PB; Saviane, C; Silver, RA1
Smothers, CT; Woodward, JJ1

Other Studies

27 other study(ies) available for 7-chlorokynurenic acid and strychnine

ArticleYear
Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
    Brain research, 1992, Feb-14, Volume: 572, Issue:1-2

    Topics: Analysis of Variance; Animals; Ataxia; Dose-Response Relationship, Drug; Feeding Behavior; Glycine; Injections, Intraventricular; Kynurenic Acid; Male; Muscle Contraction; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine

1992
Effects of strychnine-insensitive glycine receptor antagonist (7-chlorokynurenic acid) on amygdala kindling in rats.
    The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:2

    Topics: Amygdala; Analysis of Variance; Animals; Epilepsy; Kindling, Neurologic; Kynurenic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, Neurotransmitter; Strychnine

1992
In vitro and in vivo characterization of the NMDA receptor-linked strychnine-insensitive glycine site.
    Epilepsy research, 1992, Volume: 12, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Strychnine

1992
The influence of strychnine-insensitive glycine receptor agonists and antagonists on generalized seizure thresholds.
    Brain research, 1991, Mar-08, Volume: 543, Issue:1

    Topics: Alanine; Amygdala; Animals; Glycine; Kindling, Neurologic; Kynurenic Acid; Male; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine

1991
The glycine site of the N-methyl-D-aspartate receptor channel: differences between the binding of HA-966 and of 7-chlorokynurenic acid.
    Journal of neurochemistry, 1990, Volume: 54, Issue:5

    Topics: Animals; Binding Sites; Glycine; Ion Channels; Kynurenic Acid; Phencyclidine; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine

1990
Modulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex.
    British journal of pharmacology, 1990, Volume: 99, Issue:2

    Topics: Acoustic Stimulation; Animals; Aspartic Acid; Diazepam; Injections, Intraventricular; Ion Channels; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Piperazines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine

1990
Endogenous glycine modulates N-methyl-D-aspartate-evoked release of adenosine and [3H]noradrenaline from rat cortical slices.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Adenosine; Animals; Cerebral Cortex; Glycine; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Strychnine

1991
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraventricular; Kynurenic Acid; Learning; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine

1990
Stereoselective enhancement by (R)-HA-966 of the binding of [3H]CPP to the NMDA receptor complex.
    European journal of pharmacology, 1990, Sep-18, Volume: 189, Issue:2-3

    Topics: Animals; In Vitro Techniques; Kynurenic Acid; Piperazines; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spermine; Stereoisomerism; Strychnine; Synaptic Membranes

1990
Modulation of the NMDA receptor by D-serine in the cortex and the spinal cord, in vitro.
    European journal of pharmacology, 1990, Nov-20, Volume: 191, Issue:1

    Topics: Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Male; Pyrrolidinones; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Strychnine; Tetrodotoxin

1990
7-Chlorokynurenic acid, a strychnine-insensitive glycine receptor antagonist, inhibits limbic seizure kindling.
    Neuroscience letters, 1990, Oct-02, Volume: 118, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Electric Stimulation; Kindling, Neurologic; Kynurenic Acid; Limbic System; Male; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Strychnine

1990
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site.
    Brain research, 1989, Jun-05, Volume: 489, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine

1989
Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats.
    European journal of pharmacology, 1995, Jun-23, Volume: 280, Issue:1

    Topics: Animals; Behavior, Animal; Corpus Striatum; Cycloserine; Dopamine; Drug Interactions; Excitatory Amino Acid Antagonists; Kynurenic Acid; Locomotion; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Sensitivity and Specificity; Stereotyped Behavior; Strychnine

1995
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
    Journal of neurochemistry, 1993, Volume: 61, Issue:5

    Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine

1993
Drugs acting at the strychnine-insensitive glycine receptor do not induce HSP-70 protein in the cingulate cortex.
    Neuroscience letters, 1994, Feb-28, Volume: 168, Issue:1-2

    Topics: Amino Acids; Amino Acids, Cyclic; Animals; Dizocilpine Maleate; Gyrus Cinguli; Heat-Shock Proteins; Hippocampus; Immunohistochemistry; Kynurenic Acid; Male; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Strychnine

1994
Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures.
    Brain research, 1993, Feb-19, Volume: 603, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Molecular Sequence Data; Neurons; Neurotoxins; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Strychnine; Time Factors

1993
Diazepam potentiation by glycine in pentylenetetrazol seizures is antagonized by 7-chlorokynurenic acid.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:2

    Topics: Animals; Diazepam; Drug Synergism; Glycine; Injections, Intraventricular; Kynurenic Acid; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures; Strychnine

1994
Diverse modulation by systemic lidocaine of iontophoretic NMDA and quisqualic acid induced excitations on rat dorsal horn neurons.
    Neuroscience letters, 1993, Jul-23, Volume: 157, Issue:2

    Topics: Animals; Drug Synergism; Glycine; Injections, Intravenous; Iontophoresis; Kynurenic Acid; Lidocaine; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Strychnine

1993
MK-801, but not drugs acting at strychnine-insensitive glycine receptors, attenuate methamphetamine nigrostriatal toxicity.
    Brain research, 1993, Oct-15, Volume: 625, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Amino Acids, Cyclic; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Kynurenic Acid; Male; Methamphetamine; Mice; Mice, Inbred Strains; Receptors, Glycine; Strychnine; Substantia Nigra

1993
Role of the strychnine-insensitive glycine binding site in the nucleus accumbens and anterodorsal striatum in sensorimotor gating: a behavioral and microdialysis study.
    Psychopharmacology, 1997, Volume: 130, Issue:2

    Topics: Animals; Biogenic Monoamines; Chromatography, High Pressure Liquid; Dopamine; Electrochemistry; Glycine Agents; Kynurenic Acid; Male; Microdialysis; Microinjections; Neostriatum; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Reflex, Startle; Strychnine

1997
Selective depression of the spinal polysynaptic reflex by the NMDA receptor antagonists in an isolated spinal cord in vitro.
    General pharmacology, 1997, Volume: 29, Issue:4

    Topics: Animals; Depression, Chemical; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Monosynaptic; Serine; Spinal Cord; Spinal Nerve Roots; Strychnine; Valine

1997
2,3-Dihydro-6,7-dichloro-pyrido[2,3-b]pyrazine-8-oxide as selective glycine antagonist with in vivo activity.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:12

    Topics: Animals; Avoidance Learning; Binding Sites; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Mice; Motor Activity; N-Methylaspartate; Neuroprotective Agents; Pyrazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotyped Behavior; Strychnine

1997
Glycine induced calcium concentration changes in vestibular type I sensory cells.
    Hearing research, 2000, Volume: 140, Issue:1-2

    Topics: Animals; Calcium; Chelating Agents; Chlorides; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Guinea Pigs; Hair Cells, Vestibular; Kynurenic Acid; Models, Neurological; N-Methylaspartate; Strychnine

2000
Glycine receptor-mediated inhibition of dopamine and non-dopamine neurons of the rat ventral tegmental area in vitro.
    Brain research, 2001, Nov-23, Volume: 919, Issue:2

    Topics: Action Potentials; Animals; Dopamine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Kynurenic Acid; Male; Neural Inhibition; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Strychnine; Synaptic Transmission; Tetrodotoxin; Ventral Tegmental Area

2001
Glycine-induced neurotoxicity in organotypic hippocampal slice cultures.
    Experimental brain research, 2005, Volume: 161, Issue:3

    Topics: Alanine; Animals; Animals, Newborn; Brain Ischemia; Dose-Response Relationship, Drug; Drug Resistance; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Strychnine; Taurine

2005
Rapid vesicular release, quantal variability, and spillover contribute to the precision and reliability of transmission at a glomerular synapse.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Sep-07, Volume: 25, Issue:36

    Topics: Animals; Cerebellum; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Antagonists; In Vitro Techniques; Kynurenic Acid; Models, Neurological; Pyridazines; Quantum Theory; Rats; Rats, Sprague-Dawley; Strychnine; Synapses; Synaptic Transmission

2005
Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: Alanine; Animals; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Kynurenic Acid; Membrane Potentials; Mice; Mutation; Patch-Clamp Techniques; Pyrrolidinones; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Strychnine; Transfection

2007