7-chlorokynurenic acid has been researched along with serine in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 25 (69.44) | 18.2507 |
| 2000's | 10 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bostock, E; Sorrels, TL | 1 |
| Epstein, FH; Heyman, S; Rosen, S; Spokes, K | 1 |
| Berger, TW; Thiels, E; Weisz, DJ | 1 |
| Abarca, J; Bradberry, CW; Bustos, G; Forray, MI; Gysling, K; Roth, RH | 1 |
| Peeters, BW; Vanderheyden, PM | 1 |
| Lazarewicz, JW; Puka, M; Salińska, E | 1 |
| Bradford, HF; Croucher, MJ | 1 |
| Wayman, CP; Wilson, JF | 1 |
| Peterson, SL | 1 |
| Abe, K; Mizutani, A; Saito, H | 1 |
| Beart, PM; Conway, EL; Manallack, DT; Mercer, LD; O'Shea, RD | 1 |
| Oles, RJ; Singh, L; Tricklebank, MD | 1 |
| Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA | 1 |
| Keith, R; Patel, J; Salama, A; Thompson, C; Zinkand, WC | 1 |
| Brugger, F; Fagg, GE; Nassenstein-Elton, D; Olpe, HR; Pozza, MF; Wicki, U | 1 |
| Ferkany, JW; Kaplita, PV | 1 |
| Larson, J; Lynch, G; Oliver, MW | 1 |
| Ceserani, R; Gaviraghi, G; Maraia, G; Reggiani, A | 1 |
| Lehmann, JC; Procureur, D; Wood, PL | 1 |
| Woodward, JJ | 1 |
| Cattabeni, F; De Graan, PN; Di Luca, M; Gispen, WH; Ramakers, GM; Urban, IJ | 1 |
| Hirai, H; Okada, Y | 1 |
| Gebhart, GF; Kolhekar, R | 1 |
| Fujita, T; Ishizaki, K; Sudoh, M; Yoon, DM; Yoon, MH; Yoshida, N | 1 |
| Kawabe, A; Maruoka, Y; Nakamura, M; Ohno, Y; Ohtani, K; Sakamoto, H; Tamamura, C; Tanaka, H; Yasuda, H | 1 |
| Ivanovic, A; Kuhse, J; Laube, B; Reiländer, H | 1 |
| Hicks, TP; Ito, K | 1 |
| Bergeron, R; Krasteniakov, NV; Martina, M | 2 |
| Attwell, D; Billups, D | 1 |
| Lamas, M; Lee-Rivera, I; López-Colomé, AM | 1 |
| Cao, H; Guo, JD; Ji, RR; Ren, WH; Sha, H; Wang, H; Wang, PF; Zhang, YQ; Zhao, ZQ | 1 |
| Bittencourt, AS; Carobrez, AP; Santos, P; Schenberg, LC | 1 |
| Solís, JM; Suárez, LM | 1 |
| Sun, H; Wang, HL; Wang, S | 1 |
| Fernandez-Espejo, E; Moreno-Paublete, R; Portavella, M; Ramiro-Fuentes, S | 1 |
36 other study(ies) available for 7-chlorokynurenic acid and serine
| Article | Year |
|---|---|
Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
Topics: Analysis of Variance; Animals; Ataxia; Dose-Response Relationship, Drug; Feeding Behavior; Glycine; Injections, Intraventricular; Kynurenic Acid; Male; Muscle Contraction; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Strychnine | 1992 |
Mechanism of glycine protection in hypoxic injury: analogies with glycine receptor.
Topics: Animals; Dose-Response Relationship, Drug; Glycine; Hypoxia; In Vitro Techniques; Kidney; Kynurenic Acid; Male; Perfusion; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Serine | 1992 |
In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory site.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; Kynurenic Acid; Male; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine; Synapses | 1992 |
Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies.
Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Extracellular Space; Fluorometry; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Perfusion; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine | 1992 |
In vitro and in vivo characterization of the NMDA receptor-linked strychnine-insensitive glycine site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Strychnine | 1992 |
Glycine enhances extracellular 45Ca2+ response to NMDA application investigated with microdialysis of rabbit hippocampus in vivo.
Topics: Amino Acids; Animals; Calcium; Calcium Radioisotopes; Dialysis; Drug Synergism; Extracellular Space; Glycine; Hippocampus; Kynurenic Acid; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Serine | 1992 |
The influence of strychnine-insensitive glycine receptor agonists and antagonists on generalized seizure thresholds.
Topics: Alanine; Amygdala; Animals; Glycine; Kindling, Neurologic; Kynurenic Acid; Male; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine | 1991 |
Characteristics of NMDA receptors that stimulate release of hypothalamic alpha-MSH.
Topics: alpha-MSH; Animals; Hypothalamus; In Vitro Techniques; Ketamine; Kinetics; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine | 1991 |
Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Glycine; Kynurenic Acid; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine | 1991 |
Evidence for involvement of endogenous glycine in the induction of long-term potentiation in the dentate gyrus of anesthetized rats.
Topics: Anesthesia; Animals; Electric Stimulation; Glycine; Hippocampus; Kynurenic Acid; Male; Neuronal Plasticity; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Time Factors | 1991 |
Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate.
Topics: Animals; Autoradiography; Binding, Competitive; Cerebellar Cortex; Cerebral Cortex; Cycloserine; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Ligands; Male; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Serine | 1991 |
Modulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex.
Topics: Acoustic Stimulation; Animals; Aspartic Acid; Diazepam; Injections, Intraventricular; Ion Channels; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Piperazines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine | 1990 |
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Role of glycine in the N-methyl-D-aspartate-mediated neuronal cytotoxicity.
Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Serine | 1990 |
Modulation of the NMDA receptor by D-serine in the cortex and the spinal cord, in vitro.
Topics: Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Male; Pyrrolidinones; Rats; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Strychnine; Tetrodotoxin | 1990 |
Evidence for direct interactions between the NMDA and glycine recognition sites in brain.
Topics: Amino Acids; Animals; Brain Chemistry; In Vitro Techniques; Kynurenic Acid; Male; Pipecolic Acids; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Activation of the glycine site associated with the NMDA receptor is required for induction of LTP in neonatal hippocampus.
Topics: Animals; Animals, Newborn; Electric Stimulation; Electrophysiology; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine | 1990 |
Effect of 7-chloro kynurenic acid on glycine modulation of the N-methyl-D-aspartate response in guinea-pig myenteric plexus.
Topics: Animals; Aspartic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Male; Myenteric Plexus; N-Methylaspartate; Serine | 1989 |
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 1993 |
A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hippocampal slices.
Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Serine | 1994 |
The impaired long-term potentiation in the CA1 field of the hippocampus of cognitive deficient microencephalic rats is restored by D-serine.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Cognition Disorders; Electric Stimulation; Electrophysiology; Hippocampus; In Vitro Techniques; Kynurenic Acid; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Time Factors | 1993 |
Serine released from hippocampal slices during deprivation of oxygen and glucose enhances the effects of glutamate on neuronal function.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Dizocilpine Maleate; Glucose; Glutamates; Glutamic Acid; Guinea Pigs; Hippocampus; Hypoxia; In Vitro Techniques; Kynurenic Acid; Neurons; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 1993 |
Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Colon; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rectum; Serine; Skin; Spinal Cord; Synaptic Transmission | 1996 |
Intrathecally administered NMDA receptor antagonists reduce the MAC of isoflurane in rats.
Topics: Anesthetics, Inhalation; Animals; Excitatory Amino Acid Antagonists; Injections, Spinal; Isoflurane; Kynurenic Acid; Male; Piperazines; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine | 1996 |
Selective depression of the spinal polysynaptic reflex by the NMDA receptor antagonists in an isolated spinal cord in vitro.
Topics: Animals; Depression, Chemical; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Reflex, Monosynaptic; Serine; Spinal Cord; Spinal Nerve Roots; Strychnine; Valine | 1997 |
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
Topics: Animals; Baculoviridae; Binding Sites; Binding, Competitive; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indoles; Kynurenic Acid; Protein Binding; Protein Conformation; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Spodoptera | 1998 |
Effect of the glycine modulatory site of the N-methyl-D-aspartate receptor on synaptic responses in kitten visual cortex.
Topics: Animals; Binding Sites; Cats; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Glycine; Kynurenic Acid; Long-Term Potentiation; Male; Membrane Potentials; Neurons; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses; Synaptic Transmission; Visual Cortex | 2001 |
D-Serine differently modulates NMDA receptor function in rat CA1 hippocampal pyramidal cells and interneurons.
Topics: Animals; Axons; Electric Stimulation; Electrophysiology; Hippocampus; In Vitro Techniques; Interneurons; Kynurenic Acid; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Tetrodotoxin | 2003 |
Active release of glycine or D-serine saturates the glycine site of NMDA receptors at the cerebellar mossy fibre to granule cell synapse.
Topics: Animals; Animals, Newborn; Binding, Competitive; Cerebellum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Kynurenic Acid; Models, Biological; Nerve Fibers; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; Serine | 2003 |
Role of the glycine site of the N-methyl-D-aspartate receptor in synaptic plasticity induced by pairing.
Topics: Afferent Pathways; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Kynurenic Acid; Long-Term Potentiation; Neuronal Plasticity; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synapses | 2005 |
Cell-specific expression of N-methyl-D-aspartate receptor subunits in Müller glia and neurons from the chick retina.
Topics: Animals; Blotting, Western; Cells, Cultured; Chick Embryo; Glycine; Isoenzymes; Kynurenic Acid; Neuroglia; Neurons; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Retina; Reverse Transcriptase Polymerase Chain Reaction; Serine; Spermine; Synaptic Membranes | 2005 |
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect?
Topics: Animals; Anxiety; D-Amino-Acid Oxidase; Excitatory Amino Acid Antagonists; Fear; Glycine; Gyrus Cinguli; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Pain; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Stress, Psychological; Synaptic Transmission | 2006 |
Elevated T-maze evaluation of anxiety and memory effects of NMDA/glycine-B site ligands injected into the dorsal periaqueductal gray matter and the superior colliculus of rats.
Topics: Animals; Anxiety; Glycine; Kynurenic Acid; Ligands; Male; Maze Learning; Memory; Microinjections; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Stereoisomerism; Superior Colliculi | 2006 |
Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons.
Topics: Animals; Axons; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Taurine | 2006 |
D-serine relieves chronic lead exposure-impaired long-term potentiation in the CA1 region of the rat hippocampus in vitro.
Topics: Animals; Chronic Disease; Environmental Exposure; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Kynurenic Acid; Lead; Lead Poisoning, Nervous System; Long-Term Potentiation; Mossy Fibers, Hippocampal; Neuroprotective Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine | 2007 |
Role for D-serine within the ventral tegmental area in the development of cocaine's sensitization.
Topics: Analysis of Variance; Animals; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation, Enzymologic; Kynurenic Acid; Male; Microinjections; Motor Activity; Neuroprotective Agents; Rats; Rats, Wistar; Serine; Time Factors; Ventral Tegmental Area | 2008 |