7-chlorokynurenic acid and n-methylaspartate

7-chlorokynurenic acid has been researched along with n-methylaspartate in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (6.76)	18.7374
1990's	57 (77.03)	18.2507
2000's	10 (13.51)	29.6817
2010's	2 (2.70)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Nicklas, WJ; Zeevalk, GD	1
Abarca, J; Bradberry, CW; Bustos, G; Forray, MI; Gysling, K; Roth, RH	1
Lodge, D; Millar, JD; Pralong, E	1
Fink, K; Göthert, M; Schultheiss, R	1
Chapman, V; Dickenson, AH	1
Barun, S; Dalkara, T; Erdemli, G; Onur, R	1
Lazarewicz, JW; Puka, M; Salińska, E	1
DeFeo, PA; Hargrove, H; Patel, J; Salama, AI; Thompson, C; Zinkand, WC	1
Wayman, CP; Wilson, JF	1
Kemp, JA; Priestley, T	1
Collins, GG	1
Blair, R; Woodward, JJ	1
Oles, RJ; Singh, L; Tricklebank, MD	1
Ascher, P; Henderson, G; Johnson, JW	1
Haesslein, JL; Hunt, PF; Jouanen, A; Massardier, D; Tremblet, AM	1
Craig, CG; White, TD	1
Insel, TR; Skolnick, P; Trullas, R; Winslow, JT	1
Benveniste, M; Mayer, ML; Mienville, JM; Sernagor, E	1
Okamoto, K; Sakai, Y; Sekiguchi, M	1
Baimbridge, KG; Kessler, M; Lynch, G; Oliver, MW; Shacklock, JA	1
Kendall, DA; Robinson, JP	1
Dingledine, R; McNamara, D	1
Chiamulera, C; Costa, S; Reggiani, A	1
Keith, R; Patel, J; Salama, A; Thompson, C; Zinkand, WC	1
Aizenman, E; Reynolds, IJ; Rush, EA	1
Colpaert, FC; Koek, W	1
Ceserani, R; Gaviraghi, G; Maraia, G; Reggiani, A	1
Dingledine, R; Kleckner, NW	1
Harris, KM; Miller, RJ	1
Johnston, MV; McDonald, JW; Silverstein, FS; Uckele, JE	1
Foster, AC; Iversen, LL; Kemp, JA; Leeson, PD; Priestley, T; Tridgett, R; Woodruff, GN	1
Domenici, MR; Longo, R; Sagratella, S; Scotti de Carolis, A	1
Anantharam, V; Chu, B; Treistman, SN	1
MacDonald, JF; Wang, LY	1
Lehmann, JC; Procureur, D; Wood, PL	1
Flores, A; Soto, E; Vega, R	1
Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M	1
Woodward, JJ	1
Eróstegui, C; Flores, A; Soto, E; Vega, R	1
Bowser-Riley, F; Davies, SN; Shuker, MA	1
Carter, C; Fage, D; Voltz, C	1
Lux, HD; Parsons, CG; Zong, X	1
Biella, G; Lacerenza, M; Marchettini, P; Sotgiu, ML	1
Cler, JA; Cordi, AA; Dappen, MS; Emmett, MR; Gray, NM; Iyengar, S; Mick, SJ; Monahan, JB; Rao, TS; Wood, PL	1
Domenici, MR; Marinelli, S; Sagratella, S	1
Pattarini, R; Pittaluga, A; Raiteri, M; Severi, P	1
Gebhart, GF; Kolhekar, R	1
Gribkoff, VK; Molinoff, PB; Zhong, J	1
Badia, A; Clos, MV; Garcia Sanz, A; Trullas, R	1
Beninger, RJ; Boegman, RJ; Flesher, S; Jhamandas, KH; Pawley, AC	1
Johnson, SW; Wu, YN	1
Arnelle, DR; Choi, YB; D'Emilia, DM; Kim, WK; Kumar, S; Lipton, SA; Rayudu, PV; Stamler, JS	1
Bettelini, L; Corsi, M; Fina, P; Trist, DG	1
Butterfield, BS; Grewal, RS; Stanley, BG	1
Churchill, D; Jarvis, CR; Lu, WY; MacDonald, JF; MacVicar, BA; Plant, JR; Xiong, ZG	1
Mancini, L; Mennini, T; Reggiani, A; Trist, D	1
Turecek, R; Vlachová, V; Vyklický, L	1
Cugola, A; Donati, D; Micheli, F; Missio, A; Pecunioso, A; Reggiani, A; Tarzia, G	1
Capdevila, JL; Fossom, LH; Skolnick, P; Trullas, R; Viu, E; Zapata, A	1
Koch, M; Kretschmer, BD	1
Boje, KM; Lakhman, SS	1
Bertrand, S; Cazalets, JR	1
Devau, G	1
Arenare, L; Battaglia, G; Bonina, F; Bruno, V; Copani, A; Ippolito, R; La Russa, M; Nicoletti, F	1
Arenare, L; Battaglia, G; Boatto, G; Bonina, FP; Bruno, V; de Caprariis, P; Ippolito, R	1
Wu, E	1
Marszalec, W; Moriguchi, S; Narahashi, T; Yeh, JZ; Zhao, X	1
Ogonowski, AA; Smith, JB	1
Cao, H; Guo, JD; Ji, RR; Ren, WH; Sha, H; Wang, H; Wang, PF; Zhang, YQ; Zhao, ZQ	1
Solís, JM; Suárez, LM	1
Dubrovina, NI; Zinovyev, DR; Zinovyeva, DV	1
Chari, M; Cheung, GW; Kokorovic, A; Lai, TY; Lam, CK; Lam, TK; Su, BB; Wang, PY; Yang, CS	1
Harsing, LG; Kertesz, S; Levay, G; Matyus, P; Szabo, G; Udvari, S	1

Other Studies

74 other study(ies) available for 7-chlorokynurenic acid and n-methylaspartate

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Developmental differences in antagonism of NMDA toxicity by the polyamine site antagonist ifenprodil. Brain research. Developmental brain research, 1992, Feb-21, Volume: 65, Issue:2 Topics: Amino Acids; Animals; Biogenic Polyamines; Chick Embryo; Dizocilpine Maleate; Kynurenic Acid; N-Methylaspartate; Pipecolic Acids; Piperidines; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Retina	1992
Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies. Brain research, 1992, Jul-10, Volume: 585, Issue:1-2 Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Corpus Striatum; Dialysis; Dizocilpine Maleate; Extracellular Space; Fluorometry; Glutamates; Glutamic Acid; Kynurenic Acid; Male; N-Methylaspartate; Perfusion; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine	1992
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro. Neuroscience letters, 1992, Feb-17, Volume: 136, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord	1992
Stimulation of noradrenaline release in human cerebral cortex mediated by N-methyl-D-aspartate (NMDA) and non-NMDA receptors. British journal of pharmacology, 1992, Volume: 106, Issue:1 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Humans; Ibotenic Acid; Kainic Acid; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Norepinephrine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Tritium	1992
The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn. Brain research, 1992, Feb-28, Volume: 573, Issue:2 Topics: Afferent Pathways; Animals; Electric Stimulation; Hot Temperature; Injections, Spinal; Kynurenic Acid; Morphine; N-Methylaspartate; Naloxone; Nerve Fibers; Neurons; Pain; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Touch	1992
Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus. Brain research, 1992, Apr-03, Volume: 576, Issue:2 Topics: Animals; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Evoked Potentials; Glycine; Hippocampus; Iontophoresis; Ketamine; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Time Factors	1992
Glycine enhances extracellular 45Ca2+ response to NMDA application investigated with microdialysis of rabbit hippocampus in vivo. Acta neurobiologiae experimentalis, 1992, Volume: 52, Issue:2 Topics: Amino Acids; Animals; Calcium; Calcium Radioisotopes; Dialysis; Drug Synergism; Extracellular Space; Glycine; Hippocampus; Kynurenic Acid; N-Methylaspartate; Rabbits; Receptors, N-Methyl-D-Aspartate; Serine	1992
Quisqualate neurotoxicity in rat cortical cultures: pharmacology and mechanisms. European journal of pharmacology, 1992, Mar-03, Volume: 212, Issue:2-3 Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Kynurenic Acid; N-Methylaspartate; Neurons; Quinoxalines; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate	1992
Characteristics of NMDA receptors that stimulate release of hypothalamic alpha-MSH. Neuroreport, 1991, Volume: 2, Issue:8 Topics: alpha-MSH; Animals; Hypothalamus; In Vitro Techniques; Ketamine; Kinetics; Kynurenic Acid; Magnesium; Male; N-Methylaspartate; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Serine	1991
Effects of (+)-HA-966 and 7-chlorokynurenic acid on the kinetics of N-methyl-D-aspartate receptor agonist responses in rat cultured cortical neurons. Molecular pharmacology, 1991, Volume: 39, Issue:5 Topics: Animals; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Osmolar Concentration; Pyrrolidinones; Rats; Receptors, N-Methyl-D-Aspartate; Sodium	1991
Pharmacological evidence that NMDA receptors contribute to mono- and di-synaptic potentials in slices of mouse olfactory cortex. Neuropharmacology, 1991, Volume: 30, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Evoked Potentials; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Mice; N-Methylaspartate; Olfactory Bulb; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synapses	1991
Redox modulation of N-methyl-D-aspartate-stimulated neurotransmitter release from rat brain slices. Journal of neurochemistry, 1991, Volume: 57, Issue:6 Topics: Animals; Biguanides; Brain; Disulfides; Dithionitrobenzoic Acid; Dithiothreitol; Dose-Response Relationship, Drug; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Osmolar Concentration; Oxidation-Reduction; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Modulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex. British journal of pharmacology, 1990, Volume: 99, Issue:2 Topics: Acoustic Stimulation; Animals; Aspartic Acid; Diazepam; Injections, Intraventricular; Ion Channels; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Piperazines; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine; Strychnine	1990
Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor. The Journal of physiology, 1990, Volume: 430 Topics: Action Potentials; Animals; Brain; Cells, Cultured; Cerebral Cortex; Cycloserine; Diencephalon; Glycine; Ion Channels; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate	1990
GABA release from mouse striatal neurons in primary culture as a test for the functional activity of N-methyl-D-aspartate (NMDA) antagonists. Journal of neuroscience methods, 1991, Volume: 36, Issue:1 Topics: Animals; Cells, Cultured; Corpus Striatum; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Kynurenic Acid; Ligands; Mice; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate	1991
Endogenous glycine modulates N-methyl-D-aspartate-evoked release of adenosine and [3H]noradrenaline from rat cortical slices. European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1 Topics: Adenosine; Animals; Cerebral Cortex; Glycine; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Strychnine	1991
Rat pup isolation calls are reduced by functional antagonists of the NMDA receptor complex. European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Female; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Social Isolation; Vocalization, Animal	1990
Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons. Journal of neurophysiology, 1990, Volume: 63, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Aspartic Acid; Cells, Cultured; Glycine; Hippocampus; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Osmolar Concentration; Piperazines	1990
Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:7 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cerebellum; Electric Conductivity; Female; Glycine; Guinea Pigs; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Oocytes; Phencyclidine; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; RNA, Messenger; Xenopus laevis	1990
The glycine site modulates NMDA-mediated changes of intracellular free calcium in cultures of hippocampal neurons. Neuroscience letters, 1990, Jul-03, Volume: 114, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Calcium; Cells, Cultured; Embryo, Mammalian; Glycine; Hippocampus; Ketamine; Kinetics; Kynurenic Acid; Macromolecular Substances; N-Methylaspartate; Neurons; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Serine	1990
The glycine antagonist 7-chlorokynurenic acid blocks the effects of N-methyl-D-aspartate on agonist-stimulated phosphoinositide hydrolysis in guinea-pig brain slices. Journal of neurochemistry, 1990, Volume: 55, Issue:6 Topics: Animals; Brain; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; Hydrolysis; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Phosphatidylinositols; Receptors, N-Methyl-D-Aspartate	1990
Dual effect of glycine on NMDA-induced neurotoxicity in rat cortical cultures. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:12 Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Kynurenic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Degeneration; Neurons; Oocytes; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Taurine; Xenopus	1990
Effect of NMDA- and strychnine-insensitive glycine site antagonists on NMDA-mediated convulsions and learning. Psychopharmacology, 1990, Volume: 102, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Injections, Intraventricular; Kynurenic Acid; Learning; Male; Mice; N-Methylaspartate; Piperazines; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine	1990
Role of glycine in the N-methyl-D-aspartate-mediated neuronal cytotoxicity. Journal of neurochemistry, 1990, Volume: 54, Issue:3 Topics: Animals; Aspartic Acid; Cell Survival; Cells, Cultured; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Piperazines; Pyrrolidinones; Serine	1990
Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: Animals; Calcium; Dithionitrobenzoic Acid; Dithiothreitol; Dizocilpine Maleate; Fluorescence; Fura-2; Glutamates; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine	1990
Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1 Topics: Animals; Aspartic Acid; Dose-Response Relationship, Drug; Glycine; Kainic Acid; Kynurenic Acid; Male; Mice; Motor Activity; N-Methylaspartate; Oxadiazoles; Phencyclidine; Pyrrolidinones; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures	1990
Effect of 7-chloro kynurenic acid on glycine modulation of the N-methyl-D-aspartate response in guinea-pig myenteric plexus. European journal of pharmacology, 1989, Sep-01, Volume: 168, Issue:1 Topics: Animals; Aspartic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Kynurenic Acid; Male; Myenteric Plexus; N-Methylaspartate; Serine	1989
Selectivity of quinoxalines and kynurenines as antagonists of the glycine site on N-methyl-D-aspartate receptors. Molecular pharmacology, 1989, Volume: 36, Issue:3 Topics: Animals; Aspartic Acid; Binding Sites; Binding, Competitive; Biological Assay; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Structure-Activity Relationship; Xenopus laevis	1989
CNQX (6-cyano-7-nitroquinoxaline-2,3-dione) antagonizes NMDA-evoked [3H]GABA release from cultured cortical neurons via an inhibitory action at the strychnine-insensitive glycine site. Brain research, 1989, Jun-05, Volume: 489, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Strychnine	1989
Effect of glycine and glycine receptor antagonists on NMDA-induced brain injury. Neuroscience letters, 1989, Dec-15, Volume: 107, Issue:1-3 Topics: Animals; Aspartic Acid; Brain; Dose-Response Relationship, Drug; Glycine; Kynurenic Acid; N-Methylaspartate; Organ Size; Rats; Rats, Inbred Strains	1989
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:17 Topics: Animals; Animals, Newborn; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Electric Conductivity; Glycine; In Vitro Techniques; Kynurenic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1988
Felbamate selectively blocks in vitro hippocampal kainate-induced irreversible electrical changes. Life sciences, 1995, Volume: 56, Issue:21 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Electrophysiology; Felbamate; Hippocampus; Kainic Acid; Kynurenic Acid; Lamotrigine; Male; N-Methylaspartate; Pentobarbital; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar; Triazines	1995
Ethanol inhibition of recombinant heteromeric NMDA channels in the presence and absence of modulators. Journal of neurochemistry, 1995, Volume: 65, Issue:1 Topics: Animals; Electrophysiology; Ethanol; Female; Ion Channels; Kynurenic Acid; Magnesium; N-Methylaspartate; Oxidation-Reduction; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus laevis; Zinc	1995
Modulation by magnesium of the affinity of NMDA receptors for glycine in murine hippocampal neurones. The Journal of physiology, 1995, Jul-01, Volume: 486 ( Pt 1) Topics: Animals; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Hippocampus; In Vitro Techniques; Ion Channel Gating; Kynurenic Acid; Magnesium; Mice; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1995
7-Chlorokynurenate prevents NMDA-induced and kainate-induced striatal lesions. Brain research, 1993, Aug-20, Volume: 620, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Choline O-Acetyltransferase; Corpus Striatum; Dose-Response Relationship, Drug; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serine	1993
NMDA-mediated potentiation of the afferent synapse in the inner ear. Neuroreport, 1994, Oct-03, Volume: 5, Issue:15 Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Amplifiers, Electronic; Animals; Dizocilpine Maleate; Electrophysiology; Glycine; In Vitro Techniques; Kynurenic Acid; N-Methylaspartate; Neurons, Afferent; Physical Stimulation; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synapses; Vestibule, Labyrinth	1994
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures. Journal of neurochemistry, 1993, Volume: 61, Issue:5 Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine	1993
A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hippocampal slices. Journal of neurochemistry, 1994, Volume: 62, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Ethanol; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Serine	1994
Evidence for NMDA receptor in the afferent synaptic transmission of the vestibular system. Brain research, 1994, Jan-07, Volume: 633, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Ambystoma; Animals; Glycine; Hair Cells, Auditory; In Vitro Techniques; Kynurenic Acid; Magnesium; N-Methylaspartate; Nerve Fibers; Neurons, Afferent; Receptors, N-Methyl-D-Aspartate; Semicircular Canals; Synapses; Synaptic Transmission; Vestibule, Labyrinth	1994
Possible NMDA antagonist properties of drugs that affect high pressure neurological syndrome. British journal of pharmacology, 1994, Volume: 111, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Alkaloids; Animals; Benzimidazoles; High Pressure Neurological Syndrome; Hippocampus; Indole Alkaloids; Kynurenic Acid; Mephenesin; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1994
Synergism between the NMDA receptor antagonistic effects of ifenprodil and the glycine antagonist, 7-chlorokynurenate, in vivo. European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3 Topics: Animals; Chromatography, High Pressure Liquid; Drug Synergism; Glycine; Injections; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine	1994
Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization. British journal of pharmacology, 1993, Volume: 109, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Female; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses	1993
Diverse modulation by systemic lidocaine of iontophoretic NMDA and quisqualic acid induced excitations on rat dorsal horn neurons. Neuroscience letters, 1993, Jul-23, Volume: 157, Issue:2 Topics: Animals; Drug Synergism; Glycine; Injections, Intravenous; Iontophoresis; Kynurenic Acid; Lidocaine; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Strychnine	1993
Indole-2-carboxylates, novel antagonists of the N-methyl-D-aspartate (NMDA)-associated glycine recognition sites: in vivo characterization. Neuropharmacology, 1993, Volume: 32, Issue:2 Topics: Animals; Brain; Cerebellum; Cyclic GMP; Harmaline; Indoleacetic Acids; Kynurenic Acid; Ligands; Male; Mice; N-Methylaspartate; Pyrrolidinones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1993
Effects of felbamate, kynurenic acid derivatives and NMDA antagonists on in vitro kainate-induced epileptiform activity. Life sciences, 1996, May-24, Volume: 58, Issue:26 Topics: Animals; Anticonvulsants; Excitatory Amino Acid Antagonists; Felbamate; Hippocampus; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar	1996
Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120. AIDS (London, England), 1996, Volume: 10, Issue:5 Topics: Adult; Aged; Allosteric Site; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; Gene Products, env; Glycine; HIV Envelope Protein gp120; HIV-1; Humans; Kynurenic Acid; Male; Middle Aged; N-Methylaspartate; Norepinephrine; Peptide Fragments; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synaptosomes	1996
Modulation of spinal visceral nociceptive transmission by NMDA receptor activation in the rat. Journal of neurophysiology, 1996, Volume: 75, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Afferent Pathways; Animals; Colon; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Neurons; Nociceptors; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rectum; Serine; Skin; Spinal Cord; Synaptic Transmission	1996
Use of subunit-specific antisense oligodeoxynucleotides to define developmental changes in the properties of N-methyl-D-aspartate receptors. Molecular pharmacology, 1996, Volume: 50, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Base Sequence; Cerebral Cortex; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kynurenic Acid; Macromolecular Substances; Molecular Sequence Data; N-Methylaspartate; Oligonucleotides, Antisense; Oocytes; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus laevis	1996
Effect of 1-aminocyclopropanecarboxylic acid on N-methyl-D-aspartate-stimulated [3H]-noradrenaline release in rat hippocampal synaptosomes. British journal of pharmacology, 1996, Volume: 118, Issue:4 Topics: Adrenergic alpha-Antagonists; Animals; Cyclopropanes; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Tritium	1996
Differential action of NMDA antagonists on cholinergic neurotoxicity produced by N-methyl-D-aspartate and quinolinic acid. British journal of pharmacology, 1996, Volume: 117, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain; Choline O-Acetyltransferase; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Antagonism; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; N-Methylaspartate; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1996
Pharmacological characterization of inward current evoked by N-methyl-D-aspartate in dopamine neurons in the rat brain slice. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2 Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; In Vitro Techniques; Kynurenic Acid; Magnesium; Male; Membrane Potentials; N-Methylaspartate; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Sodium; Spermine; Substantia Nigra; Ventral Tegmental Area	1996
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proceedings of the National Academy of Sciences of the United States of America, 1997, May-27, Volume: 94, Issue:11 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adult; Animals; Cells, Cultured; Cerebral Cortex; Child; Dizocilpine Maleate; Embryo, Mammalian; Evoked Potentials; Glycine; Homocysteine; Humans; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1997
Estimation of the relative potency of two glycine antagonists on NMDA-induced depolarizations in BRSC and ARCS. Annals of the New York Academy of Sciences, 1997, May-30, Volume: 812 Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Potassium Chloride; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Synaptic Transmission	1997
NMDA receptor coagonist glycine site: evidence for a role in lateral hypothalamic stimulation of feeding. The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hypothalamic Area, Lateral; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1997
Neurotrophin modulation of NMDA receptors in cultured murine and isolated rat neurons. Journal of neurophysiology, 1997, Volume: 78, Issue:5 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Corpus Striatum; Dynorphins; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Ion Channel Gating; Kynurenic Acid; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Nerve Growth Factors; Neurons; Neurotrophin 3; Protein Kinase Inhibitors; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1997
GV 150526A, 7-Cl-kynurenic acid and HA 966 antagonize the glycine enhancement of N-methyl-D-aspartate-induced [3H]noradrenaline and [3H]dopamine release. European journal of pharmacology, 1997, Oct-08, Volume: 336, Issue:2-3 Topics: Animals; Dopamine; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indoles; Kynurenic Acid; Male; N-Methylaspartate; Neostriatum; Norepinephrine; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Synaptosomes	1997
Spontaneous openings of NMDA receptor channels in cultured rat hippocampal neurons. The European journal of neuroscience, 1997, Volume: 9, Issue:10 Topics: Animals; Animals, Newborn; Cells, Cultured; Evoked Potentials; Hippocampus; Ion Channel Gating; Kynurenic Acid; Likelihood Functions; Magnesium; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate	1997
2,3-Dihydro-6,7-dichloro-pyrido[2,3-b]pyrazine-8-oxide as selective glycine antagonist with in vivo activity. Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:12 Topics: Animals; Avoidance Learning; Binding Sites; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Mice; Motor Activity; N-Methylaspartate; Neuroprotective Agents; Pyrazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotyped Behavior; Strychnine	1997
Glycine site antagonists and partial agonists inhibit N-methyl-D-aspartate receptor-mediated [3H]arachidonic acid release in cerebellar granule cells. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:2 Topics: Amino Acids; Amino Acids, Cyclic; Animals; Arachidonic Acid; Cerebellum; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1998
The ventral pallidum mediates disruption of prepulse inhibition of the acoustic startle response induced by dopamine agonists, but not by NMDA antagonists. Brain research, 1998, Jul-06, Volume: 798, Issue:1-2 Topics: Acoustic Stimulation; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Globus Pallidus; Injections; Kynurenic Acid; Male; N-Methylaspartate; Neural Inhibition; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reflex, Startle	1998
Chronic dosing with 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, modulates NMDA inhibition of muscarinic-coupled PI hydrolysis in rat cortical slices. Neurochemical research, 1998, Volume: 23, Issue:9 Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hydrolysis; In Vitro Techniques; Inositol; Kynurenic Acid; Male; Muscarinic Agonists; N-Methylaspartate; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1998
Regulation by glycine, Mg2+ and polyamines of the N-methyl-D-aspartate-induced locomotion in the neonatal rat spinal cord in vitro. Neuroscience, 1999, Volume: 94, Issue:4 Topics: Animals; Biguanides; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kynurenic Acid; Magnesium; Motor Activity; Motor Neurons; N-Methylaspartate; Polyamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermine; Spinal Cord; Synapses	1999
Glycine induced calcium concentration changes in vestibular type I sensory cells. Hearing research, 2000, Volume: 140, Issue:1-2 Topics: Animals; Calcium; Chelating Agents; Chlorides; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Guinea Pigs; Hair Cells, Vestibular; Kynurenic Acid; Models, Neurological; N-Methylaspartate; Strychnine	2000
Systemically administered D-glucose conjugates of 7-chlorokynurenic acid are centrally available and exert anticonvulsant activity in rodents. Brain research, 2000, Mar-31, Volume: 860, Issue:1-2 Topics: Animals; Anticonvulsants; Astrocytes; Biotransformation; Blood-Brain Barrier; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Excitatory Amino Acid Antagonists; Galactose; Glucose; Injections, Intraperitoneal; Kynurenic Acid; Male; Mice; Microdialysis; Molecular Structure; N-Methylaspartate; Neurons; Neuroprotective Agents; Prodrugs; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship	2000
Synthesis, pharmacokinetics and anticonvulsant activity of 7-chlorokynurenic acid prodrugs. International journal of pharmaceutics, 2000, Jul-20, Volume: 202, Issue:1-2 Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Esters; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Prodrugs; Seizures	2000
Evidence against the presence of NMDA receptors at a central glutamatergic synapse in leeches. Invertebrate neuroscience : IN, 2002, Volume: 4, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Association Learning; Central Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Kynurenic Acid; Leeches; Motor Neurons; N-Methylaspartate; Neurons, Afferent; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex; Synapses; Synaptic Transmission	2002
Potentiation of N-methyl-D-aspartate-induced currents by the nootropic drug nefiracetam in rat cortical neurons. The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1 Topics: Animals; Cells, Cultured; Cerebral Cortex; Electrophysiology; Female; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Nootropic Agents; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate	2003
Behavioral effects of NMDA receptor agonists and antagonists in combination with nitric oxide-related compounds. European journal of pharmacology, 2003, Jun-20, Volume: 471, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Conditioning, Operant; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Gallic Acid; Guanidines; Indazoles; Injections, Intraperitoneal; Kynurenic Acid; Molsidomine; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroprusside; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2003
Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect? Journal of neurochemistry, 2006, Volume: 96, Issue:6 Topics: Animals; Anxiety; D-Amino-Acid Oxidase; Excitatory Amino Acid Antagonists; Fear; Glycine; Gyrus Cinguli; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Organ Culture Techniques; Pain; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Stress, Psychological; Synaptic Transmission	2006
Taurine potentiates presynaptic NMDA receptors in hippocampal Schaffer collateral axons. The European journal of neuroscience, 2006, Volume: 24, Issue:2 Topics: Animals; Axons; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Male; N-Methylaspartate; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission; Taurine	2006
N-methyl-D-aspartate receptors and amnesia in mice with depression-like state. Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:5 Topics: Amnesia; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Cycloserine; Depression; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Receptors, Amino Acid	2007
Activation of N-methyl-D-aspartate (NMDA) receptors in the dorsal vagal complex lowers glucose production. The Journal of biological chemistry, 2010, Jul-16, Volume: 285, Issue:29 Topics: 2-Amino-5-phosphonovalerate; Animals; Gene Knockdown Techniques; Glucose; Glycine; Humans; Kynurenic Acid; Liver; Male; N-Methylaspartate; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vagotomy; Vagus Nerve	2010
Temporal alteration of spreading depression by the glycine transporter type-1 inhibitors NFPS and Org-24461 in chicken retina. Brain research, 2013, Jan-25, Volume: 1492 Topics: Animals; Chickens; CHO Cells; Cortical Spreading Depression; Cricetinae; Cricetulus; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine Plasma Membrane Transport Proteins; Humans; Kynurenic Acid; N-Methylaspartate; Retina; Sarcosine	2013