Compounds > 7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
Page last updated: 2024-09-03

7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and spiperone

7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine has been researched along with spiperone in 1 studies

Compound Research Comparison

Studies
(7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)		Trials
(7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)		Recent Studies (post-2010)
(7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)		Studies
(spiperone)		Trials
(spiperone)		Recent Studies (post-2010) (spiperone)
5002,9441385

Protein Interaction Comparison

ProteinTaxonomy7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine (IC50)spiperone (IC50)
Bile salt export pumpHomo sapiens (human)10
D(2) dopamine receptorHomo sapiens (human)0.0008
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.097
D(4) dopamine receptorHomo sapiens (human)0.0005
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.097
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.097
D(3) dopamine receptorHomo sapiens (human)0.0635
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.097
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0001
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.955

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billings, JJ; Chumpradit, S; Kung, HF; Kung, MP1

Other Studies

1 other study(ies) available for 7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and spiperone

ArticleYear
Synthesis and resolution of (+-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Animals; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution

1991