7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and sch 23390

7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine has been researched along with sch 23390 in 1 studies

Compound Research Comparison

Studies (7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)	Trials (7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)	Recent Studies (post-2010) (7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)	Studies (sch 23390)	Trials (sch 23390)	Recent Studies (post-2010) (sch 23390)
5	0	0	803	0	585

Protein Interaction Comparison

Protein	Taxonomy	sch 23390 (IC50)
D(2) dopamine receptor	Homo sapiens (human)	1.0405
D	Rattus norvegicus (Norway rat)	0.001
D(1A) dopamine receptor	Homo sapiens (human)	0.0461
D(1B) dopamine receptor	Homo sapiens (human)	0.0011
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	0.0006
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	0.3891

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Billings, JJ; Chumpradit, S; Kung, HF; Kung, MP	1

Other Studies

1 other study(ies) available for 7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and sch 23390

Article	Year
Synthesis and resolution of (+-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor. Journal of medicinal chemistry, 1991, Volume: 34, Issue:3 Topics: Animals; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution	1991

Article

Year

Synthesis and resolution of (+-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor.

Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

Topics: Animals; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution

1991