Compounds > 7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
Page last updated: 2024-09-03

7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and propranolol

7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine has been researched along with propranolol in 1 studies

Compound Research Comparison

Studies
(7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)		Trials
(7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)		Recent Studies (post-2010)
(7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine)		Studies
(propranolol)		Trials
(propranolol)		Recent Studies (post-2010) (propranolol)
50033,3103,4063,218

Protein Interaction Comparison

ProteinTaxonomy7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine (IC50)propranolol (IC50)
Beta-1 adrenergic receptor Cavia porcellus (domestic guinea pig)0.0347
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0288
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)2.294
Cytochrome P450 1A2Homo sapiens (human)4
Beta-2 adrenergic receptorHomo sapiens (human)0.0114
Beta-1 adrenergic receptorHomo sapiens (human)0.0575
5-hydroxytryptamine receptor 1AHomo sapiens (human)3.9811
Beta-2 adrenergic receptorRattus norvegicus (Norway rat)0.012
Cytochrome P450 2D6Homo sapiens (human)2.9706
Beta-3 adrenergic receptorHomo sapiens (human)0.0493
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0288
Beta-1 adrenergic receptorRattus norvegicus (Norway rat)0.012
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0288
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0827
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0288
Beta-3 adrenergic receptorRattus norvegicus (Norway rat)0.012
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.466
5-hydroxytryptamine receptor 2CHomo sapiens (human)2.294
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0288
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.243
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0288
Sodium-dependent serotonin transporterHomo sapiens (human)0.38
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.342
5-hydroxytryptamine receptor 6Homo sapiens (human)3.065
Beta-2 adrenergic receptorCanis lupus familiaris (dog)0.017
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0288
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.828
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.1
Sodium/bile acid cotransporterHomo sapiens (human)5.5
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0288
GABA theta subunitRattus norvegicus (Norway rat)0.0288
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.87
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0288

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billings, JJ; Chumpradit, S; Kung, HF; Kung, MP1

Other Studies

1 other study(ies) available for 7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and propranolol

ArticleYear
Synthesis and resolution of (+-)-7-chloro-8-hydroxy-1-(3'-iodophenyl)-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine (TISCH): a high affinity and selective iodinated ligand for CNS D1 dopamine receptor.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Animals; Benzazepines; Binding, Competitive; Brain; Cell Membrane; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Tissue Distribution

1991