7-amino-4-methylcoumarin has been researched along with warfarin in 103 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (12.62) | 18.7374 |
| 1990's | 18 (17.48) | 18.2507 |
| 2000's | 35 (33.98) | 29.6817 |
| 2010's | 32 (31.07) | 24.3611 |
| 2020's | 5 (4.85) | 2.80 |
| Authors | Studies |
|---|---|
| Hoke, RA; Linn, CP; Mize, PD; Pitner, JB; Quante, JM | 1 |
| Abuknesha, RA; al-Mazeedi, HM; Price, RG | 1 |
| Kundu, GC; Wilson, IB | 1 |
| Abe, K; Tomono, Y; Watanabe, K | 1 |
| Ennis, M; Irvine, GB; Williams, CH | 1 |
| Beckmann, J; Mehlich, A; Tschesche, H; Wenzel, HR | 1 |
| Grant, AJ; Raghavan, D; Russell, PJ | 1 |
| Kohoutek, M; Kolár, Z; Kovarík, J; Krepela, E; Rypka, M; Vicar, J | 1 |
| Khorlin, AIa; Markin, VA; Nasonov, VV; Shiian, SD | 1 |
| Chrétien, M; Cromlish, JA; Hamelin, J; Johnson, DA; Marcinkiewicz, M; Seidah, NG | 1 |
| Cannon, JK; Garg, LC; Olbricht, CJ; Tisher, CC | 1 |
| Gossrau, R; Hartmann, K | 1 |
| Coombs, GH; Pupkis, MF | 1 |
| Dufek, V; Hrebícek, M; Matous, B | 1 |
| Deelder, AM; Dresden, MH; Koper, G; Ploem, JS; Rotmans, JP | 1 |
| Prakash, C; Vijay, IK | 1 |
| Kato, T; Nagatsu, T; Okada, M | 1 |
| Board, PG | 1 |
| Ebert, W; Schwartz-Albiez, R; Spiess, E; Ulbricht, B | 1 |
| Basak, A; Boudreault, A; Jean, F; Lazure, C; Seidah, NG | 1 |
| Chun, J; Goodfellow, M; Hamid, ME; Magee, JG; Minnikin, DE | 1 |
| Dauphin, C; Hamon, M; Zhou, JY | 1 |
| Brooks, E; Kalejs, U; Karlson, J; Kreishman, G; Petrova, M; Tetere, Z; Zicane, D | 1 |
| Heyduk, E; Heyduk, T | 1 |
| Nerli, B; Picó, G; Romanini, D | 1 |
| Gallagher, SP; O'Connor, B; O'Leary, RM | 1 |
| Harrow, ID; Isaac, RE; Sajid, M | 1 |
| Chiba, K; Hoshi, M; Sato, E | 1 |
| Bridges, CA; Dai, Y; Hindsgaul, O; Isogai, Y; Li, L; Whittal, RM | 1 |
| Acosta, D; Carmona, C; Goñi, F | 1 |
| Chan, VJ; McKerrow, JH; Sakanari, JA; Selzer, PM | 1 |
| Alves, LC; Davy, A; Juliano, MA; Simpson, DJ; Svendsen, I; Thomsen, KK | 1 |
| Ataullakhanov, FI; Krasotkina, YV; Sinauridze, EI | 1 |
| Coolen, MJ; Overmann, J | 1 |
| Boedeker, RH; Gonzáles, JR; Herrmann, JM; Meyle, J; Vonholdt, J | 1 |
| Chiba, H; Shimoke, K | 1 |
| Dietrich, R; Ninkovic, M; Riester, D; Schwienhorst, A; Wirsching, F | 1 |
| Bulaeva, NN; Kochukov, MY; Stroev, EA | 1 |
| Birney, YA; O'Connor, BF | 1 |
| Baba, H; Fujihara, H; Qi, S; Shimoji, K; Taga, K; Wu, C; Yamakura, T; Zhan, RZ | 1 |
| Goodman, JM; Stewart, MQ; van Dijk, R; Veenhuis, M | 1 |
| Ataullakhanov, FI; Kondratovich, AY; Pokhilko, AV | 1 |
| Ellis, KA; Hudig, D; Kam, CM; Powers, JC; Tran, TV | 1 |
| Callanan, MJ; Klaenhammer, TR; Tuler, TR | 1 |
| Brown, J; Kagawa, Y; Kurokawa, M; Shiraki, K | 1 |
| Anantharam, V; Kanthasamy, A; Kanthasamy, AG; Kaul, S; Kitazawa, M | 1 |
| Hildmann, C; Riester, D; Schwienhorst, A; Wegener, D | 1 |
| Kasili, PM; Song, JM; Vo-Dinh, T | 1 |
| He, L; Li, H; Li, Y; Liu, J; Wu, S; Yang, G; Zhong, B | 1 |
| Conn, MT; Misialek, S; Schultz, BE; Tahilramani, R; Tang, J; Wong, L; Wu, J | 1 |
| Heltweg, B; Jung, M; Trapp, J | 1 |
| Fischer, L; Patett, F | 1 |
| Hata, K; Hiwatashi, K; Hori, K; Itoh, Y; Ogasawara, H; Sugiyama, T; Tachibana, T; Takahashi, S | 1 |
| Bartley, D; Davis-Taber, R; Faltynek, C; Harlan, J; Holzman, TF; Kage, KL; Lubben, T; Pereda-Lopez, A; Richardson, PL; Scott, VE; Severin, J; Solomon, L; Surowy, CS; Traphagen, L; Vos, MH; Walter, K; Warrior, U | 1 |
| Chen, Y; Lu, Z | 1 |
| Hara, M; Kyle, R; Mitsuda, Y; Nishiyama, Y; Paul, S; Planque, S; Taguchi, H | 1 |
| Chen, X; Dong, M; Jiang, M; Liu, X; Lv, X; Zhou, J | 1 |
| Brak, K; Doyle, PS; Ellman, JA; McKerrow, JH | 1 |
| Ohta, Y; Suzuki, S; Tani, A; Yodoshi, M | 1 |
| Desaki, M; Hamachi, I; Hirayama, T; Iyoshi, S; Ojida, A; Taki, M; Yamamoto, Y | 1 |
| Al-Kindy, SM; Miller, JN | 1 |
| Abuknesha, RA; Jeganathan, F; Price, RG; Wildeboer, D | 1 |
| Chen, W; Cui, J; Ling, X; Mou, K; Xu, B; Xu, P | 1 |
| Creaven, BS; Devereux, M; Karcz, D; Kellett, A; McCann, M; Noble, A; Walsh, M | 1 |
| Chen, K; Chen, L; Feng, Y; Jiang, H; Liu, D; Luo, C; Shen, X; Wu, J | 1 |
| Hou, Q; Ling, L; Pei, Z; Wang, F; Xing, S; Zeng, J | 1 |
| Budic, M; Cigić, B; Kidric, M; Meglic, V | 1 |
| Chawla, S; Khan, MS; Khan, ZH; Qaiser, D; Singh, RD | 1 |
| Amodeo, V; Diamandis, EP; Eissa, A; Smith, CR | 1 |
| Chen, Q; Rausch, KG; Schönherr, H; Vancso, GJ | 1 |
| Kawashima, Y; Nakano, H; Sakata, T | 1 |
| Brodbelt, JS; Ko, BJ | 1 |
| Becher, T; Berdel, P; Braunstein, J; Gravius, S; Mayer, G; Müller, J; Oldenburg, J; Pötzsch, B; Rohrbach, F | 1 |
| Choi, MG; Chung, HS; Jang, SH; Lee, C; Lee, E | 1 |
| Aggarwal, N; Arya, A; Baghel, AS; Bose, M; Gupta, G; Nath, M; Parmar, VS; Pathak, R; Ponnan, P; Prasad, AK; Raj, HG; Tandon, R | 1 |
| Davies, KJ; Pickering, AM | 1 |
| Hemker, HC; Rutjes, FP; van Berkel, SS; van Delft, FL; van der Lee, B; Wagenvoord, R | 1 |
| Ambrosini, M; García Vallejo, JJ; Kalay, H; Parren, PW; van Berkel, PH; van Kooyk, Y | 1 |
| Li, B; Li, T; Li, Y; Liu, Z; Qin, D; Wang, B; Wang, M; Wang, Q; Yan, M; Yang, Z | 1 |
| Essmann, F; Huber, SM; Rudner, J; Trivigno, D | 1 |
| Bagnaresi, P; Bastos, EL; Ferreira, AG; Gonçalves, LC; Mortara, RA; Tonelli, RR | 1 |
| Fang, GM; Huang, Y; Li, JB; Li, YT; Liang, J; Liu, L | 1 |
| Hayakawa, T; Ikeda, N; Kakehi, K; Nagata, M; Nishida, N; Suzuki, S; Yamaguchi, N; Yodoshi, M | 1 |
| Asada, Y; Kinoshita, M; Nagai, E; Suzuki, S; Yamamoto, S | 1 |
| Mallik, S; Srivastava, DK; Sule, NV; Ugrinov, A | 1 |
| Chmurzyński, L; Jacewicz, D; Wiczk, W; Zaborowski, B; Żamojć, K | 1 |
| Roslev, P; Ørsted, M | 1 |
| He, B; Huang, W; Li, Y; Xie, T; You, L | 1 |
| He, B; Huang, W; Li, Y; Liu, J; You, L; Zhu, H | 1 |
| Hanaoka, K; Kawaguchi, M; Komatsu, T; Kuriki, Y; Nagano, T; Nakada, A; Onagi, J; Terai, T; Ueno, T; Urano, Y; Yoshioka, K | 1 |
| Callewaert, M; De Malsche, W; Desmet, G; Ottevaere, H | 1 |
| Acres, RG; Feyer, V; Plekan, O; Prince, KC; Wang, F; Wickrama Arachchilage, AP | 1 |
| Finel, M; Ge, GB; Järvinen, E; Troberg, J; Yang, L | 1 |
| Bryant, JR; Toro, TB; Watt, TJ | 1 |
| Cui, H; He, Y; Hu, Z; Wen, H; Wu, F; Xue, N; Zhang, G | 1 |
| Bernatowicz, M; Bolkun, L; Galar, M; Kalita, J; Kloczko, J; Ostrowska, H; Romaniuk, W | 1 |
| Galisteo-González, F; Martínez, A; Medina-O'Donnell, M; Molina-Bolívar, JA; Parra, A; Ruiz, CC | 1 |
| Cadel, S; Darmon, C; Désert, A; Foulon, T; Ghélis, T; Lafont, R; Mahbouli, M; Piesse, C | 1 |
| Baca, M; De Malsche, W; Gelin, P; Kryj, A; Laha, P; Naghdi, E; Ottevaere, H; Sukas, S; Terryn, H | 1 |
| Laguna, R; Matos, MJ; Rodríguez-Enríquez, F; Uriarte, E; Viña, D | 1 |
| Figueiredo, F; Macedo-Ribeiro, S; Martins, PM; Pereira, PJB; Pinto, MF; Pombinho, AR; Rocha, F; Silva, A | 1 |
| Feinhals, A; Friedrichs, JJ; Hey-Hawkins, E; Kellert, M; Lönnecke, P; Tepper, J; Ullrich, NA | 1 |
| Guo, Y; Li, H; Sun, X; Wen, R | 1 |
1 trial(s) available for 7-amino-4-methylcoumarin and warfarin
| Article | Year |
|---|---|
Microassay for the detection of elastase activity in the gingival crevice.
Topics: Adult; Clinical Enzyme Tests; Coumarins; Double-Blind Method; Fluorometry; Gingival Crevicular Fluid; Gingivitis; Humans; Indicators and Reagents; Leukocyte Elastase; Male; Periodontal Index; Prospective Studies; Regression Analysis; Statistics, Nonparametric; Substrate Specificity | 2001 |
102 other study(ies) available for 7-amino-4-methylcoumarin and warfarin
| Article | Year |
|---|---|
Synthesis of serine-AMC-carbamate: a fluorogenic tryptophanase substrate.
Topics: Coumarins; Fluorescent Dyes; Indicators and Reagents; Kinetics; Molecular Structure; Serine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophanase | 1992 |
AMC-anti-FITC conjugates: novel reagents for amplified immunochemical techniques. Immunofluorescent staining of human fibroblasts.
Topics: Animals; Antibodies; Coumarins; Fibroblasts; Fibronectins; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique; Humans; Immunoglobulin G; Immunohistochemistry; Indicators and Reagents; Rabbits; Sensitivity and Specificity; Sheep; Staining and Labeling | 1992 |
Identification of endothelin converting enzyme in bovine lung membranes using a new fluorogenic substrate.
Topics: Animals; Aspartic Acid Endopeptidases; Cattle; Cell Membrane; Chromatography, Affinity; Chromatography, High Pressure Liquid; Coumarins; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Kinetics; Lung; Metalloendopeptidases; Oligopeptides; Protein Precursors; Substrate Specificity | 1992 |
High-performance liquid affinity chromatography and in situ fluorescent labeling on thin-layer chromatography of glycosphingolipids.
Topics: Animals; Boronic Acids; Chromatography, Affinity; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Colitis; Coumarins; Fluorescent Dyes; Glycosphingolipids; Humans; Liver Cirrhosis; Microchemistry; Rats | 1990 |
Visual detection of peptidase activity using fluorogenic substrates in a microtiter plate assay.
Topics: Aminopeptidases; Animals; Coumarins; Fluorescence; Helix, Snails; Microchemistry; Oligopeptides; Ultraviolet Rays | 1990 |
Aprotinin derivatives with chromophoric leaving groups can be used as highly selective active-site titrants for serine proteinases and permit the determination of kinetic constants of enzyme-inhibitor complexes.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Aprotinin; Binding Sites; Chromatography, High Pressure Liquid; Chymotrypsin; Coumarins; Fluorometry; Humans; Indicators and Reagents; Kallikreins; Kinetics; Leukocytes; Lysine; Molecular Sequence Data; Pancreatic Elastase; Serine Endopeptidases; Spectrophotometry; Trypsin | 1988 |
Elastase activities of human bladder cancer cell lines derived from high grade invasive tumours.
Topics: Alanine; Animals; Carcinoma, Transitional Cell; Cell Line; Coumarins; Humans; Membrane Proteins; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Pancreatic Elastase; Protease Inhibitors; Substrate Specificity; Urinary Bladder Neoplasms | 1989 |
Clinical experience with the testing of serum proteinase activity by cathepsin B-like sensitive amino acid derivatives of 7-amino-4-methylcoumarine.
Topics: Adult; Breast Neoplasms; Cathepsin B; Colonic Neoplasms; Coumarins; Cysteine; Edetic Acid; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Male; Middle Aged; Neoplasm Staging; Peptide Hydrolases; Protease Inhibitors; Rectal Neoplasms | 1987 |
[Fluorescent derivatives of carbohydrates in the analysis of the structure of glycoconjugates. N-(4-methylcoumarin-7-yl) glycamines in the study of asparagine-bound carbohydrate chains of glycoproteins].
Topics: Asparagine; Chromatography, High Pressure Liquid; Coumarins; Fluorescent Dyes; Glycoproteins; Hydrolysis; Oligosaccharides | 1987 |
Human pituitary tryptase: molecular forms, NH2-terminal sequence, immunocytochemical localization, and specificity with prohormone and fluorogenic substrates.
Topics: Amino Acid Sequence; Binding Sites; Coumarins; Electrophoresis, Polyacrylamide Gel; Fluoresceins; Fluorescent Dyes; Histocytochemistry; Humans; Hydrogen-Ion Concentration; Immunologic Tests; Kinetics; Lung; Macromolecular Substances; Mast Cells; Molecular Weight; Peptide Fragments; Peptide Hydrolases; Pituitary Gland; Protein Precursors; Sodium Chloride; Substrate Specificity | 1987 |
Activities of cathepsins B and L in isolated nephron segments from proteinuric and nonproteinuric rats.
Topics: Aging; Animals; Cathepsin B; Cathepsin L; Cathepsins; Coumarins; Cysteine Endopeptidases; Endopeptidases; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Nephrons; Protease Inhibitors; Proteinuria; Rats; Rats, Inbred Strains; Reference Values; Serum Albumin, Bovine; Sex Characteristics; Time Factors | 1986 |
[Suitability of amino methylcoumarin and naphthylamine substrates for microchemical peptidase determination].
Topics: 2-Naphthylamine; Aminopeptidases; CD13 Antigens; Chemical Phenomena; Chemistry; Coumarins; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Fluorometry; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Naphthalenes; Trypsin | 1983 |
Purification and characterization of proteolytic enzymes of Leishmania mexicana mexicana amastigotes and promastigotes.
Topics: Animals; Chromatography, Gel; Chromatography, Ion Exchange; Coumarins; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Leishmania; Peptide Hydrolases; Protease Inhibitors; Substrate Specificity | 1984 |
[Fluorometric determination of serum levels of cathepsin B using 7-amino-4-methylcoumarin as the specific substrate].
Topics: Adult; Cathepsin B; Cathepsins; Coumarins; Female; Fluorometry; Humans; Male; Substrate Specificity | 1983 |
Automated measurement of proteinase activity with a fluorogenic substrate using an inverted fluorescence microscope.
Topics: Coumarins; Dipeptides; Endopeptidases; Indicators and Reagents; Microscopy, Fluorescence; Photometry; Schistosoma mansoni | 1982 |
A new fluorescent tag for labeling of saccharides.
Topics: Acetylglucosamine; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Coumarins; Disaccharides; Glucosamine; Glycoside Hydrolases; Hydrolysis; Spectrometry, Fluorescence; Trisaccharides | 1983 |
Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues.
Topics: Brain; Cerebral Cortex; Chromatography, Gel; Copper; Coumarins; Dipeptides; Endopeptidases; Humans; Kidney; Molecular Weight; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Tissue Distribution; Zinc | 1980 |
The use of fluorogenic peptide substrates for the detection of coagulation factors II and X after electrophoresis.
Topics: Coumarins; Electrophoresis, Agar Gel; Factor X; Humans; Indicators and Reagents; Oligopeptides; Prothrombin | 1982 |
Quantification of intracellular cathepsin activities in human lung tumor cell lines by flow cytometry.
Topics: 2-Naphthylamine; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cathepsin B; Cathepsin L; Cathepsins; Coumarins; Cysteine Endopeptidases; Endopeptidases; Flow Cytometry; Humans; Indicators and Reagents; Lung Neoplasms; Rhodamines; Substrate Specificity; Tumor Cells, Cultured | 1995 |
Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor.
Topics: Amino Acid Sequence; Aspartic Acid Endopeptidases; Catalysis; Coumarins; Fluorescent Dyes; Furin; Humans; Hydrolysis; Molecular Sequence Data; Oligopeptides; Proprotein Convertases; Substrate Specificity; Subtilisins | 1995 |
Rapid characterisation and identification of mycobacteria using fluorogenic enzyme tests.
Topics: Clinical Enzyme Tests; Coumarins; Fluorescent Dyes; Mycobacterium; Nocardia | 1994 |
[Use of 7-amino-4-methylcoumarin for the spectrophotometric determination of nitrites].
Topics: Amines; Coumarins; Nitrites; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1993 |
Side reactions in the pyroglutamic acid-7-amino-4-methylcoumarin synthesis.
Topics: Chlorides; Coumarins; Dicyclohexylcarbodiimide; Phosphorus; Phosphorus Compounds; Pyrrolidonecarboxylic Acid | 1996 |
Thiol-reactive, luminescent Europium chelates: luminescence probes for resonance energy transfer distance measurements in biomolecules.
Topics: Base Sequence; Chelating Agents; Coumarins; Edetic Acid; Energy Transfer; Europium; Fluorescent Dyes; Luminescent Measurements; Metals, Rare Earth; Pentetic Acid; Polydeoxyribonucleotides; Spectrometry, Fluorescence; Sulfhydryl Reagents | 1997 |
Structural specificity requirements in the binding of beta lactam antibiotics to human serum albumin.
Topics: Acid-Base Equilibrium; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Binding Sites; Binding, Competitive; Cephalosporins; Coumarins; Esterases; Fatty Acids; Glycosylation; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indicators and Reagents; Kinetics; Ligands; Lysine; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Ultrafiltration | 1997 |
The development of two fluorimetric assays for the determination of pyroglutamyl aminopeptidase type-II activity.
Topics: Aminopeptidases; Animals; Cattle; Coumarins; Cyclization; Dipeptidyl Peptidase 4; Oligopeptides; Pyrrolidonecarboxylic Acid; Spectrometry, Fluorescence | 1997 |
Purification and properties of a membrane aminopeptidase from Ascaris suum muscle that degrades neuropeptides AF1 and AF2.
Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Ascaris suum; Cell Membrane; Chromatography, Ion Exchange; Coumarins; Hydrolysis; Isoelectric Point; Kinetics; Molecular Weight; Muscle, Skeletal; Neuropeptides; Peptides; Protease Inhibitors; Solubility | 1997 |
Detection of in vivo proteasome activity in a starfish oocyte using membrane-impermeant substrate.
Topics: Adenine; Aminopeptidases; Animals; Cell Membrane Permeability; Coumarins; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytosol; Fluorescent Dyes; Hydrolysis; Kinetics; Leucine; Leupeptins; Meiosis; Mesylates; Multienzyme Complexes; Oligopeptides; Oocytes; Proteasome Endopeptidase Complex; Spectrometry, Fluorescence; Starfish | 1997 |
Matrix-assisted laser desorption ionization mass spectrometry for the analysis of monosulfated oligosaccharides.
Topics: Azo Compounds; Carbohydrate Conformation; Carbohydrate Sequence; Coumaric Acids; Coumarins; Molecular Sequence Data; N-Acetylneuraminic Acid; Oligosaccharides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfates; Thymine; Triazines | 1997 |
Characterization and partial purification of a leucine aminopeptidase from Fasciola hepatica.
Topics: Animals; Cattle; Chromatography, Affinity; Chromatography, Gel; Coumarins; Deoxycholic Acid; Electrophoresis, Polyacrylamide Gel; Fasciola hepatica; Histocytochemistry; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Leucyl Aminopeptidase; Metals; Molecular Weight; Protease Inhibitors; Substrate Specificity | 1998 |
Expression and alteration of the S2 subsite of the Leishmania major cathepsin B-like cysteine protease.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cathepsin B; Coumarins; Dipeptides; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Leishmania major; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Pichia; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Sulfones | 1999 |
Purification and characterization of barley dipeptidyl peptidase IV.
Topics: Amino Acid Sequence; Chromatography, Ion Exchange; Coumarins; Dipeptidyl Peptidase 4; Electrophoresis, Polyacrylamide Gel; Hordeum; Hydrogen-Ion Concentration; Peptides; Substrate Specificity | 2000 |
Spatiotemporal dynamics of fibrin formation and spreading of active thrombin entering non-recalcified plasma by diffusion.
Topics: alpha-Macroglobulins; Antithrombins; Arginine; Blood Coagulation; Calcium; Coumarins; Diffusion; Fibrin; Fibrinogen; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Kinetics; Models, Theoretical; Pipecolic Acids; Plasma; Solutions; Sulfonamides; Thrombin | 2000 |
Functional exoenzymes as indicators of metabolically active bacteria in 124,000-year-Old sapropel layers of the eastern Mediterranean Sea.
Topics: Alkaline Phosphatase; Aminopeptidases; Bacteria; beta-Glucosidase; Colony Count, Microbial; Coumarins; Fluorescent Dyes; Fossils; Geologic Sediments; Hymecromone; Kinetics; Mediterranean Sea; Seawater; Water Microbiology | 2000 |
Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Chloromethyl Ketones; Amino Acid Substitution; Animals; Apoptosis; Caspase 3; Caspases; Chromones; Coumarins; Cysteine Proteinase Inhibitors; Dopamine Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Genes, Dominant; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; Mutagenesis, Site-Directed; Neoplasm Proteins; Nerve Growth Factor; Oligopeptides; Parkinson Disease; Parkinsonian Disorders; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Fusion Proteins; Signal Transduction; Transfection | 2001 |
Fluorogenic assay for penicillin G acylase activity.
Topics: Coumarins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorescent Dyes; Indicators and Reagents; Penicillin Amidase; Recombinant Fusion Proteins; Sensitivity and Specificity; Spectrometry, Fluorescence; Time Factors | 2001 |
Intracellular distribution and regulation of calpains in the thyroid gland.
Topics: Animals; Calcium; Calpain; Cell Fractionation; Cell Membrane; Coumarins; Indicators and Reagents; Male; Rats; Thyroid Gland; Thyrotropin | 2001 |
Purification and characterization of a Z-pro-prolinal-insensitive Z-Gly-Pro-7-amino-4-methyl coumarin-hydrolyzing peptidase from bovine serum--a new proline-specific peptidase.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Coumarins; Dimerization; Dipeptides; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Prolyl Oligopeptidases; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity | 2001 |
Sublethal cerebral ischemia inhibits caspase-3 activation induced by subsequent prolonged ischemia in the C57Black/Crj6 strain mouse.
Topics: Animals; Brain Ischemia; Caspase 3; Caspase Inhibitors; Caspases; Corpus Striatum; Coumarins; Enzyme Activation; Ischemic Preconditioning; Mice; Mice, Inbred C57BL; Neurons; Prosencephalon; Reperfusion; Time Factors | 2001 |
Monomeric alcohol oxidase is preferentially digested by a novel protease from Candida boidinii.
Topics: Alcohol Oxidoreductases; Binding Sites; Candida; Centrifugation, Density Gradient; Chromatography; Coumarins; Endopeptidases; Enzyme Stability; Hydrogen-Ion Concentration; Indicators and Reagents; Peptides; Peroxisomes; Protease Inhibitors; Protein Folding; Substrate Specificity | 2002 |
Spatiotemporal dynamics of contact activation factors of blood coagulation.
Topics: Algorithms; Binding Sites; Blood Coagulation; Cluster Analysis; Coumarins; Enzyme Activation; Factor XIa; Glass; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Models, Theoretical; Plasma Kallikrein; Polystyrenes; Temperature; Time Factors | 2002 |
Dipeptidyl peptidase I: importance of progranzyme activation sequences, other dipeptide sequences, and the N-terminal amino group of synthetic substrates for enzyme activity.
Topics: Catalytic Domain; Cathepsin C; Coumarins; Hydrogen-Ion Concentration; Kinetics; Substrate Specificity | 2002 |
Overexpression of peptidases in Lactococcus and evaluation of their release from leaky cells.
Topics: Aminopeptidases; Bacterial Proteins; Cloning, Molecular; Coumarins; DNA Restriction Enzymes; Escherichia coli; Gene Expression; Genetic Vectors; Glutamyl Aminopeptidase; Lactococcus; Lactococcus lactis; Metalloendopeptidases; Oligopeptides; Peptide Hydrolases; Plasmids; Promoter Regions, Genetic; Substrate Specificity; Transformation, Bacterial | 2002 |
Cytokine-regulatory activity and therapeutic efficacy of cinnamyl derivatives in endotoxin shock.
Topics: Animals; Coumarins; Cytokines; Female; Lipopolysaccharides; Mice; Mice, Inbred DBA; Propanols; Shock, Septic | 2003 |
Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Benzimidazoles; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Line; Coumarins; Cytochromes c; DNA Fragmentation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Gene Expression; Herbicides; In Vitro Techniques; Manganese Compounds; Mesencephalon; Metalloporphyrins; Nerve Degeneration; Organometallic Compounds; Oxidative Stress; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Rats; Reactive Oxygen Species; Time Factors; Transfection | 2003 |
Improved fluorogenic histone deacetylase assay for high-throughput-screening applications.
Topics: Acetylation; Amidohydrolases; Animals; Coumarins; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescent Dyes; Fluorometry; Histone Deacetylases; Hydroxamic Acids; Kinetics; Liver; Rats; Trypsin | 2003 |
Optical sensor for the detection of caspase-9 activity in a single cell.
Topics: Aminolevulinic Acid; Apoptosis; Biosensing Techniques; Breast Neoplasms; Caspase 9; Caspases; Cell Line, Tumor; Coumarins; Humans; Microscopy, Fluorescence; Nanotechnology; Oligopeptides; Optics and Photonics; Photochemotherapy | 2004 |
High pressure effects on the emission properties and crystal structure of coumarin 120.
Topics: Coumarins; Crystallization; Crystallography, X-Ray; Fluorescence; Phase Transition; Pressure; Spectrum Analysis; Time Factors | 2004 |
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases.
Topics: Binding Sites; Binding, Competitive; Coumarins; Enzyme Activation; Enzyme Inhibitors; Histone Deacetylase 1; Histone Deacetylase 2; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Isoenzymes; Kinetics; Lysine; Phosphorylation; Recombinant Proteins; Repressor Proteins; Substrate Specificity | 2004 |
In vitro assays for the determination of histone deacetylase activity.
Topics: Animals; Catalysis; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Coumarins; Histone Deacetylases; Histones; Humans; Isotopes; NAD; Radioisotopes; Sirtuins; Spectrometry, Fluorescence | 2005 |
delta-(D -alpha-Aminoadipoyl)-cleaving amidase of Ochrobactrum anthropi.
Topics: 2-Aminoadipic Acid; Amidohydrolases; Biodegradation, Environmental; Cell Division; Cell Fractionation; Cell Membrane; Cephalosporins; Coumarins; Molecular Structure; Nitrogen Compounds; Ochrobactrum anthropi; Transglutaminases | 2005 |
Paenidase, a novel D-aspartyl endopeptidase from Paenibacillus sp. B38: purification and substrate specificity.
Topics: Anilides; Aniline Compounds; Aspartic Acid; Aspartic Acid Endopeptidases; Bacillaceae; Coumarins; Enzyme Activation; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Molecular Sequence Data; Molecular Weight; Protease Inhibitors; Substrate Specificity; Temperature | 2006 |
A high throughput fluorescent assay for measuring the activity of fatty acid amide hydrolase.
Topics: Amidohydrolases; Automation; Biological Assay; Coumarins; Fluorescent Dyes; Humans; Indicators and Reagents; Reproducibility of Results | 2007 |
Dye sensitized luminescent europium nanoparticles and its time-resolved fluorometric assay for DNA.
Topics: Chemical Phenomena; Chemistry, Physical; Coloring Agents; Coumarins; DNA; Emulsions; Europium; Magnetics; Microspheres; Models, Chemical; Nanoparticles; Oligonucleotides; Pentetic Acid; Silicon Dioxide; Spectrometry, Fluorescence | 2007 |
Naturally occurring catalytic antibodies: evidence for preferred development of the catalytic function in IgA class antibodies.
Topics: Amino Acid Sequence; Antibodies, Catalytic; Catalysis; Coumarins; Humans; Hydrolysis; Immunoglobulin A; Immunoglobulin G; Peptides; Saliva; Serine Proteinase Inhibitors; Serum; Substrate Specificity | 2007 |
Antimicrobial activity of an endophytic Xylaria sp.YX-28 and identification of its antimicrobial compound 7-amino-4-methylcoumarin.
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Candida albicans; Coumarins; Ginkgo biloba; Gram-Negative Bacteria; Gram-Positive Bacteria; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillium; Xylariales | 2008 |
Identification of a new class of nonpeptidic inhibitors of cruzain.
Topics: Amino Acid Sequence; Animals; Cathepsins; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Design; Ketones; Macrophages; Mice; Molecular Sequence Data; Protozoan Proteins; Sequence Alignment; Structure-Activity Relationship; Sulfones; Triazoles; Trypanosoma cruzi | 2008 |
Optimized conditions for high-performance liquid chromatography analysis of oligosaccharides using 7-amino-4-methylcoumarin as a reductive amination reagent.
Topics: Chromatography, High Pressure Liquid; Coumarins; Fluorometry; Monosaccharides; Oligosaccharides; Polysaccharides; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2008 |
Fluorescence imaging of intracellular cadmium using a dual-excitation ratiometric chemosensor.
Topics: Biosensing Techniques; Cadmium; Coumarins; Ethylenediamines; Fluorescent Dyes; HeLa Cells; Humans; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
High-performance liquid chromatography determination of nitrated polycyclic aromatic hydrocarbons by indirect fluorescence detection.
Topics: Azo Compounds; Chromatography, High Pressure Liquid; Coumarins; Fluorescence; Fluorescent Dyes; Linear Models; Naphthols; Nitro Compounds; Polycyclic Aromatic Hydrocarbons; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Water | 2009 |
Characterization of bacterial proteases with a panel of fluorescent peptide substrates.
Topics: Bacterial Proteins; Coumarins; Fluorescent Dyes; Kinetics; Peptide Hydrolases; Peptides; Protease Inhibitors; Pseudomonas aeruginosa; Substrate Specificity | 2009 |
Capillary electrophoresis for screening of 20S proteasome inhibitors.
Topics: Animals; Coumarins; Drug Evaluation, Preclinical; Electrophoresis, Capillary; Esters; Hydrolysis; Inhibitory Concentration 50; Leupeptins; Linear Models; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rabbits; Reproducibility of Results | 2009 |
Copper(II) complexes of coumarin-derived Schiff bases and their anti-Candida activity.
Topics: Aldehydes; Antifungal Agents; Candida albicans; Chelating Agents; Copper; Coumarins; Crystallography, X-Ray; Drug Design; Ligands; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Organometallic Compounds; Schiff Bases; Spectrophotometry; Transition Temperature | 2009 |
A fluorometric assay of SIRT1 deacetylation activity through quantification of nicotinamide adenine dinucleotide.
Topics: Catechin; Coumarins; Fluorescent Dyes; NAD; Peptides; Resveratrol; Sirtuin 1; Spectrometry, Fluorescence; Stilbenes | 2009 |
Endostatin expression in neurons during the early stage of cerebral ischemia is associated with neuronal apoptotic cell death in adult hypertensive rat model of stroke.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Caspase 3; Cathepsin B; Coumarins; Dipeptides; Disease Models, Animal; Endostatins; Enzyme Inhibitors; Hypertension; Infarction, Middle Cerebral Artery; Male; Neurons; Random Allocation; Rats; Rats, Sprague-Dawley; Stroke; Time Factors | 2010 |
A quantitative technique for determining proteases and their substrate specificities and pH optima in crude enzyme extracts.
Topics: Aminopeptidases; Arginine; Coumarins; Electrophoresis, Polyacrylamide Gel; Enzyme Assays; Fluorescent Dyes; Hydrogen-Ion Concentration; Peptide Hydrolases; Phaseolus; Plant Extracts; Plant Leaves; Plant Proteins; Substrate Specificity | 2009 |
Förster's resonance energy transfer between Fullerene C60 and Coumarin C440.
Topics: Coumarins; Dimerization; Fluorescence Resonance Energy Transfer; Fullerenes; Models, Biological; Models, Molecular; Spectrometry, Fluorescence | 2010 |
Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade.
Topics: Amino Acid Sequence; Antimicrobial Cationic Peptides; Biocatalysis; Cell Differentiation; Coumarins; Enzyme Activation; Enzyme Precursors; Epidermal Cells; Epidermis; Gene Expression Regulation, Enzymologic; Humans; Hydrogen-Ion Concentration; Kallikreins; Keratinocytes; Kinetics; Models, Molecular; Molecular Sequence Data; Protease Inhibitors; Protein Conformation; Recombinant Proteins; Substrate Specificity; Sweat | 2011 |
α-Chymotrypsin-catalyzed reaction confined in block-copolymer vesicles.
Topics: Acrylic Resins; Biocatalysis; Chymotrypsin; Coumarins; Hydrolysis; Kinetics; Nanotechnology; Polymers; Polystyrenes; Spectrophotometry, Ultraviolet | 2010 |
Solvent effect on the absorption spectra of coumarin 120 in water: A combined quantum mechanical and molecular mechanical study.
Topics: Coumarins; Molecular Dynamics Simulation; Quantum Theory; Solvents; Spectrum Analysis; Water | 2011 |
Ultraviolet photodissociation of chromophore-labeled oligosaccharides via reductive amination and hydrazide conjugation.
Topics: Amination; Coumarins; Hydrazines; Oligosaccharides; Photochemical Processes; Tandem Mass Spectrometry; Ultraviolet Rays | 2011 |
Profiling of active thrombin in human blood by supramolecular complexes.
Topics: Aptamers, Nucleotide; Arginine; Binding Sites; Blood Coagulation; Coumarins; Enzyme Assays; Humans; Limit of Detection; Peptides; Pipecolic Acids; Sensitivity and Specificity; Sulfonamides; Thrombin | 2011 |
A fluorogenic method for measuring enteropeptidase activity: spectral shift in the emission of GD4K-conjugated 7-amino-4-methylcoumarin.
Topics: 2-Naphthylamine; Amino Acid Sequence; Animals; Cattle; Coumarins; Enteropeptidase; Fluorescent Dyes; Kinetics; Molecular Sequence Data; Peptides; Spectrum Analysis | 2011 |
Characterization of 7-amino-4-methylcoumarin as an effective antitubercular agent: structure-activity relationships.
Topics: Antitubercular Agents; Cell Wall; Coumarins; Drug Resistance, Multiple, Bacterial; Drug Synergism; Ethambutol; Isoniazid; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Mycolic Acids; Rifampin; Streptomycin; Structure-Activity Relationship | 2011 |
A simple fluorescence labeling method for studies of protein oxidation, protein modification, and proteolysis.
Topics: Animals; Borohydrides; Carboxylic Acids; Cells, Cultured; Coumarins; Enzyme Assays; Fluorescent Dyes; Mice; Oxidation-Reduction; Oxidative Stress; Peptide Hydrolases; Protein Denaturation; Protein Processing, Post-Translational; Protein Stability; Proteins; Proteolysis; Spectrometry, Fluorescence; Staining and Labeling | 2012 |
Fluorogenic peptide-based substrates for monitoring thrombin activity.
Topics: Amides; Coumarins; Dipeptides; Factor Xa; Fluorescent Dyes; Humans; Hydrolysis; Kinetics; Malonates; Peptides; Thrombin; Triazoles | 2012 |
Online nanoliquid chromatography-mass spectrometry and nanofluorescence detection for high-resolution quantitative N-glycan analysis.
Topics: Antibodies, Monoclonal; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Coumarins; Fluorescent Dyes; Glycoproteins; Glycosylation; Nanotechnology; Polysaccharides; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization | 2012 |
Magnetic nanoparticles modified with DTPA-AMC-rare earth for fluorescent and magnetic resonance dual mode imaging.
Topics: Animals; Contrast Media; Coumarins; Europium; Gadolinium; HeLa Cells; Humans; Liver; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Microscopy, Fluorescence; Pentetic Acid; Spectrometry, Fluorescence | 2012 |
Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1.
Topics: Apoptosis; Blotting, Western; Coumarins; Flow Cytometry; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunoenzyme Techniques; Immunoprecipitation; Jurkat Cells; Membrane Potential, Mitochondrial; Myeloid Cell Leukemia Sequence 1 Protein; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Radiation, Ionizing; RNA, Small Interfering; Tumor Stem Cell Assay; Ubiquitin; Ubiquitin Thiolesterase | 2012 |
A nature-inspired betalainic probe for live-cell imaging of Plasmodium-infected erythrocytes.
Topics: Animals; Betalains; Biomimetic Materials; Cell Survival; Coumarins; Erythrocytes; Fluorescent Dyes; Mice; Microscopy, Fluorescence; Molecular Imaging; Plasmodium falciparum; Pyridines | 2013 |
New semi-synthesis of ubiquitin C-terminal conjugate with 7-amino-4-methylcoumarin.
Topics: Chemistry Techniques, Synthetic; Coumarins; Electrophoresis, Polyacrylamide Gel; Molecular Structure; Recombinant Proteins; Ubiquitin C | 2014 |
A novel condition for capillary electrophoretic analysis of reductively aminated saccharides without removal of excess reagents.
Topics: Animals; Cattle; Chickens; Coumarins; Electrophoresis, Capillary; Glycoproteins; Humans; Limit of Detection; Monosaccharides; Oligosaccharides | 2013 |
A rapid and highly sensitive microchip electrophoresis of mono- and mucin-type oligosaccharides labeled with 7-amino-4-methylcoumarin.
Topics: Coumarins; Electrophoresis, Microchip; Glycoproteins; Oligosaccharides; Sensitivity and Specificity | 2015 |
Bridging of a substrate between cyclodextrin and an enzyme's active site pocket triggers a unique mode of inhibition.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Aminopeptidases; beta-Cyclodextrins; Binding Sites; Biocatalysis; Catalytic Domain; Coumarins; Crystallography, X-Ray; Cyclodextrins; Enzyme Inhibitors; Escherichia coli Proteins; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Spectrophotometry; Substrate Specificity | 2015 |
Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives.
Topics: Coumarins; Cyclic N-Oxides; Fluorescence; Kinetics; Spectrometry, Fluorescence | 2015 |
A fluorescence-based hydrolytic enzyme activity assay for quantifying toxic effects of Roundup® to Daphnia magna.
Topics: Alkaline Phosphatase; Animals; Chromates; Coumarins; Daphnia; Enzymes; Fluorescent Dyes; Herbicides; Hydrolysis; Potassium Compounds; Toxicity Tests; Umbelliferones; Water Pollutants, Chemical | 2015 |
A FRET-based assay for screening SIRT5 specific modulators.
Topics: Amino Acid Sequence; Coumarins; Enzyme Assays; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kinetics; Molecular Sequence Data; p-Dimethylaminoazobenzene; Peptides; Sirtuins; Substrate Specificity | 2015 |
A FRET-based assay for screening SIRT6 modulators.
Topics: Coumarins; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Molecular Structure; Sirtuins; Structure-Activity Relationship | 2015 |
Identification of tissue-restricted bioreaction suitable for in vivo targeting by fluorescent substrate library-based enzyme discovery.
Topics: Anilides; Carboxylesterase; Coumarins; Enzyme Activation; Fluorescence; Humans; Kidney; Liver; Substrate Specificity | 2015 |
Detailed kinetic performance analysis of micromachined radially elongated pillar array columns for liquid chromatography.
Topics: Chromatography, Liquid; Coumarins; Diffusion; Kinetics; Lab-On-A-Chip Devices; Permeability | 2016 |
X-ray Photoemission Spectra and Electronic Structure of Coumarin and its Derivatives.
Topics: 4-Hydroxycoumarins; Carbon; Coumarins; Isomerism; Oxygen; Photoelectron Spectroscopy; Quantum Theory | 2016 |
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
Topics: Animals; Blotting, Western; Camptothecin; Chromatography, High Pressure Liquid; Coumarins; Diclofenac; Estradiol; Estrone; Flavonoids; Glucuronosyltransferase; Humans; Hymecromone; Intestinal Mucosa; Irinotecan; Kinetics; Microsomes, Liver | 2017 |
Lysine Deacetylases Exhibit Distinct Changes in Activity Profiles Due to Fluorophore Conjugation of Substrates.
Topics: Coumarins; Histone Deacetylases; Humans; Substrate Specificity | 2017 |
Exploration of the Fluorescent Properties and the Modulated Activities against Sirtuin Fluorogenic Assays of Chromenone-Derived Natural Products.
Topics: Coumarins; Flavones; Fluorescence; Humans; Isoflavones; Sirtuin 1 | 2018 |
High chymotrypsin-like activity in the plasma of patients with newly diagnosed multiple myeloma treated with bortezomib is predictive of a better response and longer PFS.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bortezomib; Combined Modality Therapy; Coumarins; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Targeted Therapy; Multiple Myeloma; Neoplasm Proteins; Proportional Hazards Models; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Serine Endopeptidases; Treatment Outcome | 2018 |
Maslinic acid conjugate with 7-amino-4-methylcoumarin as probe to monitor the temperature dependent conformational changes of human serum albumin by FRET.
Topics: Circular Dichroism; Coumarins; Fluorescence Resonance Energy Transfer; Hot Temperature; Humans; Hydrogen-Ion Concentration; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence | 2019 |
The effects of curcumin, mangiferin, resveratrol and other natural plant products on aminopeptidase B activity.
Topics: Aminopeptidases; Animals; Biological Products; Coumaric Acids; Coumarins; Curcumin; Kinetics; Molecular Docking Simulation; Protease Inhibitors; Rats; Recombinant Proteins; Resveratrol; Xanthones | 2019 |
Performance of laterally elongated pillar array columns in capillary electrochromatography mode.
Topics: Capillary Electrochromatography; Coumarins; Equipment Design; Lab-On-A-Chip Devices | 2020 |
7-Amidocoumarins as Multitarget Agents against Neurodegenerative Diseases: Substitution Pattern Modulation.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Coumarins; Drug Design; Humans; Hydrogen Peroxide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Rats; Structure-Activity Relationship | 2021 |
Major Improvements in Robustness and Efficiency during the Screening of Novel Enzyme Effectors by the 3-Point Kinetics Assay.
Topics: Artifacts; Ataxin-3; Coumarins; Deubiquitinating Enzymes; Drug Discovery; Drug Repositioning; Enzyme Activators; Enzyme Inhibitors; Enzymes; High-Throughput Screening Assays; Humans; Kinetics; Repressor Proteins; Sensitivity and Specificity; Ubiquitin | 2021 |
Modular Synthetic Approach to Carboranyl‒Biomolecules Conjugates.
Topics: Amines; Boron Compounds; Carboxylic Acids; Coumarins; Folic Acid; Glycine | 2021 |
A highly sensitive and selective ratiometric sensing platform based on 7-amino-4-methylcoumarin for naked-eye visual fluorescence sensing of Cu
Topics: Coumarins; Fluorescent Dyes; Quantum Dots; Spectrometry, Fluorescence | 2022 |