7 alpha-hydroxy-4-cholesten-3-one has been researched along with simvastatin in 3 studies
| Studies (7 alpha-hydroxy-4-cholesten-3-one) | Trials (7 alpha-hydroxy-4-cholesten-3-one) | Recent Studies (post-2010) (7 alpha-hydroxy-4-cholesten-3-one) | Studies (simvastatin) | Trials (simvastatin) | Recent Studies (post-2010) (simvastatin) |
|---|---|---|---|---|---|
| 134 | 28 | 59 | 8,442 | 1,730 | 3,630 |
| Protein | Taxonomy | 7 alpha-hydroxy-4-cholesten-3-one (IC50) | simvastatin (IC50) |
|---|---|---|---|
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | 1.164 | |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | 4.426 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.7843 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 9.5 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0034 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0034 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0111 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 0.049 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikegami, T; Kano, M; Matsuzaki, Y; Miyamoto, J; Miyazaki, H; Osuga, T; Shoda, J; Tanaka, N | 1 |
| Anzivino, C; Bertolotti, M; Carulli, L; Carulli, N; Corna, F; Del Puppo, M; Gabbi, C; Kienle, MG; Loria, P; Pellegrini, E; Ricchi, M; Zambianchi, L | 1 |
| Ahrens, N; Black, A; Matysik, S; Orsó, E; Schmitz, G | 1 |
3 other study(ies) available for 7 alpha-hydroxy-4-cholesten-3-one and simvastatin
| Article | Year |
|---|---|
Simultaneous determination of plasma mevalonate and 7alpha-hydroxy-4-cholesten-3-one levels in hyperlipoproteinemia: convenient indices for estimating hepatic defects of cholesterol and bile acid syntheses and biliary cholesterol supersaturation.
Topics: Adult; Aged; Bile; Bile Acids and Salts; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Hyperlipoproteinemias; Intestinal Absorption; Liver; Lovastatin; Male; Mevalonic Acid; Middle Aged; RNA, Messenger; Simvastatin | 1997 |
Correlation between plasma levels of 7alpha-hydroxy-4-cholesten-3-one and cholesterol 7alpha-hydroxylation rates in vivo in hyperlipidemic patients.
Topics: Aged; Anticholesteremic Agents; Bezafibrate; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Complement C4; Data Interpretation, Statistical; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Kinetics; Male; Middle Aged; Reference Standards; Simvastatin | 2008 |
Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report.
Topics: Adult; Blood Chemical Analysis; Blood Component Removal; Chenodeoxycholic Acid; Cholestenones; Follow-Up Studies; Humans; Lipoproteins, LDL; Male; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous | 2011 |