7 alpha-hydroxy-4-cholesten-3-one has been researched along with atorvastatin in 3 studies
| Studies (7 alpha-hydroxy-4-cholesten-3-one) | Trials (7 alpha-hydroxy-4-cholesten-3-one) | Recent Studies (post-2010) (7 alpha-hydroxy-4-cholesten-3-one) | Studies (atorvastatin) | Trials (atorvastatin) | Recent Studies (post-2010) (atorvastatin) |
|---|---|---|---|---|---|
| 134 | 28 | 59 | 7,420 | 2,058 | 3,782 |
| Protein | Taxonomy | 7 alpha-hydroxy-4-cholesten-3-one (IC50) | atorvastatin (IC50) |
|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.0064 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0002 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0002 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0054 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 4.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Axelson, M; Dunn, S; Naoumova, RP; Neuwirth, CK; O'Neill, FH; Taylor, GW; Thompson, GR | 1 |
| Bourbon, M; Knight, BL; Naoumova, RP; Neuwirth, CK; O'Neill, FH; Patel, DD; Soutar, AK; Taylor, GW; Thompson, GR | 1 |
| Adachi, R; Amano, Y; Ishikawa, E; Miura, S; Shimada, M; Shinozawa, E; Tozawa, R | 1 |
2 trial(s) available for 7 alpha-hydroxy-4-cholesten-3-one and atorvastatin
| Article | Year |
|---|---|
Effect of inhibiting HMG-CoA reductase on 7 alpha-hydroxy-4-cholesten-3-one, a marker of bile acid synthesis: contrasting findings in patients with and without prior up-regulation of the latter pathway.
Topics: Anticholesteremic Agents; Atorvastatin; Bile Acids and Salts; Biomarkers; Cholestenones; Female; Heptanoic Acids; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Jejunoileal Bypass; Lipids; Lipoproteins; Male; Mevalonic Acid; Middle Aged; Pyrroles; Up-Regulation | 1999 |
Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia.
Topics: Anticholesteremic Agents; Atorvastatin; Cholestenones; Cholesterol, LDL; Cholestyramine Resin; Colestipol; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hyperlipoproteinemia Type II; Male; Mevalonic Acid; Middle Aged; Mutation; Pyrroles; Receptors, LDL; RNA, Messenger | 2001 |
1 other study(ies) available for 7 alpha-hydroxy-4-cholesten-3-one and atorvastatin
| Article | Year |
|---|---|
Combinational effects of farnesoid X receptor antagonist and statin on plasma lipid levels and low-density lipoprotein clearance in guinea pigs.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Benzoates; Cholestenones; Cholesterol; Cholesterol, LDL; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, HDL; Male; Pyrazoles; Pyrroles; Receptors, Cytoplasmic and Nuclear; Time Factors | 2014 |