Page last updated: 2024-09-04

7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene and benzo(a)pyrene

7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene has been researched along with benzo(a)pyrene in 2 studies

*Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke. [MeSH]

*Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke. [MeSH]

Compound Research Comparison

Studies
(7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene)
Trials
(7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene)
Recent Studies (post-2010)
(7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene)
Studies
(benzo(a)pyrene)
Trials
(benzo(a)pyrene)
Recent Studies (post-2010) (benzo(a)pyrene)
16007,311172,154

Protein Interaction Comparison

ProteinTaxonomy7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene (IC50)benzo(a)pyrene (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.04
Amine oxidase [flavin-containing] AHomo sapiens (human)5.972

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, FM1
Alekseyev, YO; Dzantiev, L; Romano, LJ1

Other Studies

2 other study(ies) available for 7,8-dihydroxy-9,10-epoxy-8-methyl-7,8,9,10-tetrahydrobenzo(a)pyrene and benzo(a)pyrene

ArticleYear
Denaturation and renaturation studies of benzo[a]pyrene metabolite modified DNAs.
    Biochemistry, 1987, Jul-14, Volume: 26, Issue:14

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; Circular Dichroism; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Isomerism; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Polydeoxyribonucleotides; Spectrometry, Fluorescence

1987
Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation.
    Biochemistry, 2001, Feb-20, Volume: 40, Issue:7

    Topics: Benzo(a)pyrene; Benzopyrenes; Binding Sites; Catalysis; Deoxyguanosine; DNA Adducts; DNA Polymerase I; DNA Primers; DNA, Bacterial; Electrophoresis; Escherichia coli; Hydrolysis; Kinetics; Mutagens; Stereoisomerism; Templates, Genetic; Trypsin

2001