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7,8-dihydromethysticin and kavain

7,8-dihydromethysticin has been researched along with kavain in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (35.29)18.2507
2000's5 (29.41)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elzaawely, AA; Fukuta, M; Tawata, S; Xuan, TD1
Hermanson, DL; Shaik, AA; Xing, C1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Berger, M; Grunze, H; von Wegerer, J; Walden, J; Winter, U1
Grunze, H; Walden, J1
Beck, MA; Boonen, G; Häberlein, H1
Friese, J; Gleitz, J1
Boonen, G; Ferger, B; Häberlein, H; Kuschinsky, K1
Boonen, G; Häberlein, H1
Bueter, B; Bueter, KB; Dinh, LD; Lundstrom, K; Schaffner, W; Simmen, U1
Benet, LZ; Cummins, C; Holzgrabe, U; Jacobsen, W; Unger, M1
Blanchfield, JT; Bone, KM; Lehmann, RP; Matthias, A; Penman, KG; Toth, I1
Fu, S; Ramzan, I; Rowe, A1
Ahmad, R; Amin, A; Apers, S; Exarchou, V; Hermans, N; Pieters, L; Tuenter, E; Upadhyay, A1
Ganzera, M; Murauer, A1
Avery, BA; Eans, SO; Fujioka, N; Haddad, L; McLaughlin, J; Narayanapillai, SC; Sharma, A; Stacy, HM; Wang, Y; Xing, C1
Brown, PN; Liu, Y; Lund, JA; Murch, SJ1

Other Studies

17 other study(ies) available for 7,8-dihydromethysticin and kavain

ArticleYear
Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum).
    Journal of agricultural and food chemistry, 2006, Feb-08, Volume: 54, Issue:3

    Topics: Colletotrichum; Fungicides, Industrial; Fusarium; Gas Chromatography-Mass Spectrometry; Herbicides; Kava; Lactones; Plant Roots; Plants; Trichoderma

2006
Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity.
    Bioorganic & medicinal chemistry letters, 2009, Oct-01, Volume: 19, Issue:19

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Kava; NF-kappa B; Pyrans

2009
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Effects of kawain and dihydromethysticin on field potential changes in the hippocampus.
    Progress in neuro-psychopharmacology & biological psychiatry, 1997, Volume: 21, Issue:4

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; Membrane Potentials; Pyrones

1997
Reduction of the frequency of occurrence of low magnesium induced field potentials in the hippocampus slice preparation of guinea pigs: a good screening tool for calcium antagonistic effects of anticonvulsant and antipsychotic drugs.
    Magnesium research, 1997, Volume: 10, Issue:2

    Topics: Animals; Anticonvulsants; Antipsychotic Agents; Buspirone; Calcium Channel Blockers; Carbamazepine; Drug Evaluation, Preclinical; Epilepsy; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Lamotrigine; Magnesium; Male; Pyrimidines; Pyrones; Triazines

1997
Contribution to the quantitative and enantioselective determination of kavapyrones by high-performance liquid chromatography on ChiraSpher NT material.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Nov-21, Volume: 702, Issue:1-2

    Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Pyrans; Pyrones; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism

1997
Kavain, dihydrokavain, and dihydromethysticin non-competitively inhibit the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels.
    Planta medica, 1998, Volume: 64, Issue:5

    Topics: Animals; Batrachotoxins; Cerebral Cortex; Ion Channel Gating; Male; Protein Binding; Pyrones; Rats; Rats, Wistar; Sodium Channels; Synaptosomes; Tritium

1998
In vivo effects of the kavapyrones (+)-dihydromethysticin and (+/-)-kavain on dopamine, 3,4-dihydroxyphenylacetic acid, serotonin and 5-hydroxyindoleacetic acid levels in striatal and cortical brain regions.
    Planta medica, 1998, Volume: 64, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Cerebral Cortex; Corpus Striatum; Dopamine; Hydroxyindoleacetic Acid; Male; Pyrones; Rats; Serotonin

1998
Influence of genuine kavapyrone enantiomers on the GABA-A binding site.
    Planta medica, 1998, Volume: 64, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Bicuculline; Cerebral Cortex; Plants, Medicinal; Pyrans; Pyrones; Rats; Receptors, GABA-A; Stereoisomerism; Tritium

1998
Interaction of various Piper methysticum cultivars with CNS receptors in vitro.
    Planta medica, 2001, Volume: 67, Issue:4

    Topics: Animals; Brain; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Cricetinae; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Kava; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal; Pyrans; Pyrones; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Dopamine D2; Receptors, GABA-A; Receptors, Histamine; Receptors, Opioid; Receptors, Serotonin; Semliki forest virus

2001
Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava).
    Planta medica, 2002, Volume: 68, Issue:12

    Topics: Anisoles; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Kava; Lactones; Mass Spectrometry; Molecular Structure; Phytotherapy; Plant Extracts; Pyrans; Pyrones; Rhizome

2002
Permeability studies of Kavalactones using a Caco-2 cell monolayer model.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:3

    Topics: Biological Availability; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Humans; Kava; Kinetics; Lactones; Models, Biological; Molecular Structure; Plant Extracts; Pyrans; Pyrones; Rhizome

2007
Kavalactone metabolism in rat liver microsomes.
    Phytotherapy research : PTR, 2012, Volume: 26, Issue:7

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Female; Isoenzymes; Male; Membrane Proteins; Microsomes, Liver; Pyrans; Pyrones; Rats; Rats, Sprague-Dawley; Sex Factors

2012
Kavalactones, a novel class of protein glycation and lipid peroxidation inhibitors.
    Planta medica, 2014, Volume: 80, Issue:12

    Topics: Animals; Caenorhabditis elegans; Chelating Agents; Glucose; Glycation End Products, Advanced; Glycosylation; Guanidines; Lactones; Linoleic Acid; Lipid Peroxidation; Lipoproteins, LDL; Longevity; Oxidative Stress; Plant Extracts; Pyrans; Pyrones; Thiobarbituric Acid Reactive Substances

2014
Quantitative Determination of Lactones in Piper methysticum (Kava-Kava) by Supercritical Fluid Chromatography.
    Planta medica, 2017, Volume: 83, Issue:12-13

    Topics: Chromatography, Supercritical Fluid; Kava; Lactones; Molecular Structure; Plant Roots; Pyrans; Pyrones

2017
A stable isotope dilution tandem mass spectrometry method of major kavalactones and its applications.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Animals; Humans; Kava; Lactones; Male; Mice; Mice, Inbred C57BL; Pyrones; Radioisotope Dilution Technique; Tandem Mass Spectrometry; Tissue Distribution; Urinalysis

2018
Single-Lab Validation for Determination of Kavalactones and Flavokavains in Piper methysticum (Kava).
    Planta medica, 2018, Volume: 84, Issue:16

    Topics: Calibration; Chromatography, High Pressure Liquid; Dietary Supplements; Kava; Lactones; Limit of Detection; Plant Roots; Pyrans; Pyrones

2018