7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with guanine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.86) | 18.7374 |
| 1990's | 12 (42.86) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broyde, S; Geacintov, NE; Greenberg, JP; Hingerty, BE; Singh, SB; Singh, UC | 1 |
| Bernelot-Moens, C; Glickman, BW; Gordon, AJ | 1 |
| Marsch, GA; Rill, RL | 1 |
| Basu, AK; Benasutti, M; Essigmann, JM; Green, CL; Loechler, EL | 1 |
| Aulmann, W; Doerjer, G; Oesch, F; Platt, KL | 1 |
| Dixon, K; Gielen, JE; Levine, AS; Roilides, E; Tuteja, N | 1 |
| Pullman, B; Zakrzewska, K | 1 |
| Burbaum, JJ; Dommen, J; Miller, KJ; Taylor, ER | 1 |
| Bickers, DR; Hopfinger, AJ; Malhotra, D; Nakata, Y | 1 |
| Geacintov, NE; Jelinsky, SA; Liu, T; Loechler, EL | 1 |
| Birke, S; Geacintov, NE; Li, B; Mao, B; Swenberg, CE; Xu, J; Xu, R | 1 |
| Drouin, EE; Lech, J; Loechler, EL | 1 |
| Chary, P; Han, S; Harris, CM; Harris, TM; Kim, SJ; Latham, GJ; Lloyd, RS; Robberson, DL | 1 |
| Ariese, F; Geacintov, NE; Jankowiak, R; Mao, B; Small, GJ; Suh, M | 1 |
| Loechler, EL; Rodriguez, H | 1 |
| Denissenko, MF; Pao, A; Pfeifer, GP; Tang, M | 1 |
| Das, A; Gopalakrishnan, S; Tang, KS; Tomasz, M; Waring, MJ | 1 |
| Jiricny, J; Maher, VM; Marra, G; McCormick, JJ; Zhang, H | 1 |
| Broyde, S; Perlow, RA | 1 |
| Amin, S; Geacintov, NE; Kolbanovskiy, A; Zhuang, P | 1 |
| Kohno, T; Murakami, H; Nojima, Y; Saitoh, T; Shinmura, K; Shinmura, Y; Sunaga, N; Yamaguchi, S; Yamane, A; Yokota, J; Yoshimura, K | 1 |
| Jansson, I; Rusling, JF; Schenkman, JB; Wang, B | 1 |
| Geacintov, NE; Wang, J; Wang, Z; Zhao, B | 1 |
| Chang, JH; Cheng, YW; Chiang, CC; Chou, MC; Lai, TJ; Lee, H; Tsai, YY | 1 |
| Guza, R; Matter, B; Tretyakova, N | 1 |
| Glick, J; Lin, Y; Noronha, AM; Vouros, P; Wilds, CJ; Xiong, W | 1 |
| Amin, S; Dissanayake, T; Giambasu, GM; Guza, R; Hudson, RH; Jankowiak, R; Jones, R; Kotandeniya, D; Lad, RR; Lin, C; Murphy, K; Sturla, SJ; Tretyakova, NY; Wojciechowski, F; York, DM | 1 |
| Burrows, CJ; Fleming, AM; Johnson, RP; Perera, RT; White, HS | 1 |
1 review(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and guanine
| Article | Year |
|---|---|
The role of carcinogen DNA adduct structure in the induction of mutations.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; DNA; DNA Adducts; DNA Damage; Guanine; Models, Molecular; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Thymine | 1990 |
27 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and guanine
| Article | Year |
|---|---|
Structures of the (+)- and (-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne adducts to guanine-N2 in a duplex dodecamer.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Computer Simulation; DNA; DNA Damage; Guanine; Models, Molecular; Nucleic Acid Conformation; Thermodynamics; Water | 1991 |
Induction of specific frameshift and base substitution events by benzo[a]pyrene diol epoxide in excision-repair-deficient Escherichia coli.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Composition; Base Sequence; Cytosine; Dihydroxydihydrobenzopyrenes; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutation; Thymine | 1990 |
Sequence preferences of covalent DNA binding by anti-(+)- and anti-(-)-benzo[a]pyrene diol epoxides.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Composition; Base Sequence; Chemical Phenomena; Chemistry; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Guanine; Hydrogen-Ion Concentration; Methods; Molecular Sequence Data; Piperidines; Stereoisomerism; Structure-Activity Relationship | 1990 |
Individual differences in DNA repair capacities in man.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylation; Cells, Cultured; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; DNA Repair; Guanine; Humans; Kinetics; Lymphocytes | 1987 |
Mutational specificity of benzo[a]pyrene diolepoxide in monkey cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Composition; Base Sequence; Cell Line; Chlorocebus aethiops; Dihydroxydihydrobenzopyrenes; DNA Damage; Fibroblasts; Genetic Vectors; Guanine; Kidney; Molecular Sequence Data; Mutation | 1988 |
Sequence selectivity, a test of the nature of the covalent adduct formed between benzo[a]pyrene and DNA.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Benzo(a)pyrene; Carcinogens; Chemical Phenomena; Chemistry, Physical; DNA; Guanine; Intercalating Agents; Models, Molecular; Thermodynamics | 1987 |
Stereoselectivity of benzo[a]pyrene diol epoxides by DNA for adduct formation with N2 on guanine.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzopyrenes; DNA; Guanine; Nitrogen; Stereoisomerism | 1985 |
Intercalation of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene enantiomeric isomers with dinucleoside dimers: a basis for alkylation of the 2-amino group in guanine.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylation; Benzopyrenes; Deoxyribonucleosides; Guanine; Intercalating Agents; Nucleic Acid Conformation; Stereoisomerism | 1983 |
The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G-->A and G-->C, in addition to G-->T, mutations.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Adducts; Escherichia coli; Genes, Bacterial; Guanine; Molecular Sequence Data; Mutagenesis, Insertional; Mutagens; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Restriction Mapping; Structure-Activity Relationship; Thymine | 1995 |
Stereochemistry-dependent bending in oligonucleotide duplexes induced by site-specific covalent benzo[a]pyrene diol epoxide-guanine lesions.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenosine Triphosphate; Base Sequence; DNA Damage; Electrophoresis, Polyacrylamide Gel; Guanine; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Spectrum Analysis; Stereoisomerism | 1995 |
The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide can be unstable in double-stranded DNA.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; DNA; DNA Adducts; DNA, Single-Stranded; Guanine; Hot Temperature; Hydrogen-Ion Concentration; Magnesium; Mass Spectrometry; Molecular Sequence Data; Oligodeoxyribonucleotides | 1995 |
In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Sequence; Binding Sites; Blotting, Southern; Codon; DNA; DNA Adducts; DNA Primers; DNA Repair; DNA Replication; Escherichia coli; Genes, ras; Guanine; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Stereoisomerism; Templates, Genetic | 1995 |
Flanking base effects on the structural conformation of the (+)-trans-anti-benzo[a]pyrene diolepoxide adduct to N2-dG in sequence-defined oligonucleotides.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Benzo(a)pyrene; Benzopyrenes; Cold Temperature; DNA Adducts; DNA Damage; Electrophoresis, Polyacrylamide Gel; Guanine; Molecular Conformation; Molecular Sequence Data; Molecular Structure; Mutation; Nucleic Acid Conformation; Oligonucleotides | 1994 |
Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: what controls mutagenic specificity?
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Composition; Base Sequence; DNA, Bacterial; Escherichia coli; Frameshift Mutation; Freezing; Guanine; Hot Temperature; Molecular Sequence Data; Mutagenesis; Plasmids; Transformation, Bacterial | 1993 |
Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Cells, Cultured; Codon; DNA Adducts; DNA Damage; DNA Repair; Endodeoxyribonucleases; Escherichia coli Proteins; Exons; Fibroblasts; Genes, p53; Guanine; Humans; Kinetics; Molecular Sequence Data; Neoplasms; Point Mutation; Polymerase Chain Reaction; Thymine; Transcription, Genetic | 1998 |
Reactivity of guanine at m5CpG steps in DNA: evidence for electronic effects transmitted through the base pairs.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylation; Cross-Linking Reagents; DNA; DNA Fragmentation; Guanine; Magnetic Resonance Spectroscopy; Mitomycin; Mutation; Nucleic Acid Conformation | 1999 |
Mismatch repair is required for O(6)-methylguanine-induced homologous recombination in human fibroblasts.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Pair Mismatch; Carcinogens; Cell Line; DNA; DNA Adducts; DNA Damage; DNA Repair; Fibroblasts; Guanine; Humans; Methylnitronitrosoguanidine; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Recombination, Genetic | 2000 |
Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bacteriophage T7; Base Pair Mismatch; Base Pairing; Benzo(a)pyrene; Binding Sites; Carcinogens, Environmental; Computer Simulation; Deoxyadenine Nucleotides; DNA Adducts; DNA Damage; DNA Primers; DNA Replication; DNA-Directed DNA Polymerase; Genes, p53; Guanine; Hydrogen Bonding; Magnesium; Models, Molecular; Mutagenesis; Protein Conformation; Software; Stereoisomerism; Templates, Genetic | 2001 |
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Carcinogens, Environmental; Catalysis; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA Damage; DNA Polymerase I; DNA Primers; DNA Replication; Guanine; Kinetics; Mutagenesis; Mutagens; Polydeoxyribonucleotides; Pyrimidine Nucleotides; Sequence Analysis, DNA; Templates, Genetic; Thymine Nucleotides | 2001 |
Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Carbon-Oxygen Lyases; DNA Glycosylases; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Guanine; Humans; N-Glycosyl Hydrolases; Point Mutation; Tumor Cells, Cultured | 2003 |
Evaluating enzymes that generate genotoxic benzo[a]pyrene metabolites using sensor arrays.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Biosensing Techniques; Camphor 5-Monooxygenase; Chromatography, Liquid; Cytochrome P-450 CYP1A2; DNA; DNA Damage; Electrochemistry; Electrodes; Enzymes; Guanine; Horses; Humans; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Mutagens; Myoglobin; Organometallic Compounds; Oxidation-Reduction; Polyethylenes; Pseudomonas putida; Quaternary Ammonium Compounds | 2005 |
Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA-Directed DNA Polymerase; DNA, Fungal; Guanine; Models, Genetic; Mutagenesis; Nucleotidyltransferases; Point Mutation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymine | 2006 |
An association between BPDE-like DNA adduct levels and P53 gene mutation in pterygium.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aged; Aged, 80 and over; Deoxyguanosine; DNA Adducts; Female; Genes, p53; Guanine; Humans; Immunohistochemistry; Male; Middle Aged; Mutation; Pterygium; Staining and Labeling; Thymine; Tissue Distribution; Tumor Suppressor Protein p53 | 2006 |
Endogenous cytosine methylation and the formation of carcinogen carcinogen-DNA adducts.
Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Pairing; Carcinogens; CpG Islands; Cytosine; Deoxyguanosine; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Stereoisomerism | 2008 |
The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.
Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analytic Sample Preparation Methods; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; Codon; Cytosine; DNA; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Humans; Microchemistry; Mutagens; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2009 |
Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Pairing; Chromatography, High Pressure Liquid; Cytosine; Deoxyguanosine; DNA Adducts; Genes, p53; Guanine; Isotope Labeling; Models, Molecular; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2011 |
Detection of benzo[a]pyrene-guanine adducts in single-stranded DNA using the α-hemolysin nanopore.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylating Agents; Benzo(a)pyrene; DNA Adducts; DNA, Single-Stranded; Genome; Glass; Guanine; Hemolysin Proteins; Humans; Ions; Lipid Bilayers; Metals; Mutagenesis; Mutagens; Nanopores; Nanotechnology; Neoplasms; Oligonucleotides | 2015 |