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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and cytosine

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with cytosine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (33.33)18.2507
2000's5 (41.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bernelot-Moens, C; Glickman, BW; Gordon, AJ1
Geacintov, NE; Jelinsky, SA; Liu, T; Loechler, EL1
Romano, LJ; Weisenberger, DJ1
Gräslund, A; Jernström, B; Pradhan, P; Seidel, A1
Amin, S; Colgate, KC; Geacintov, NE; Huang, X; Kolbanovskiy, A1
Feng, Z; Hu, W; Tang, MS1
Bonala, RR; Dong, H; Grollman, AP; Johnson, F; Shibutani, S; Suzuki, N1
Guza, R; Matter, B; Tretyakova, N1
Glick, J; Lin, Y; Noronha, AM; Vouros, P; Wilds, CJ; Xiong, W1
Amin, S; Dissanayake, T; Giambasu, GM; Guza, R; Hudson, RH; Jankowiak, R; Jones, R; Kotandeniya, D; Lad, RR; Lin, C; Murphy, K; Sturla, SJ; Tretyakova, NY; Wojciechowski, F; York, DM1
Danell, AS; Hvastkovs, EG; Satterwhite, JE; Trumbo, CM1
Choudhary, D; Fu, YJ; Kadimisetty, K; Malla, S; Rusling, JF; Schenkman, JB1

Other Studies

12 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and cytosine

ArticleYear
Induction of specific frameshift and base substitution events by benzo[a]pyrene diol epoxide in excision-repair-deficient Escherichia coli.
    Carcinogenesis, 1990, Volume: 11, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Composition; Base Sequence; Cytosine; Dihydroxydihydrobenzopyrenes; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Guanine; Molecular Sequence Data; Mutation; Thymine

1990
The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G-->A and G-->C, in addition to G-->T, mutations.
    Biochemistry, 1995, Oct-17, Volume: 34, Issue:41

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenine; Base Sequence; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Adducts; Escherichia coli; Genes, Bacterial; Guanine; Molecular Sequence Data; Mutagenesis, Insertional; Mutagens; Oligodeoxyribonucleotides; Plasmids; Point Mutation; Restriction Mapping; Structure-Activity Relationship; Thymine

1995
Cytosine methylation in a CpG sequence leads to enhanced reactivity with Benzo[a]pyrene diol epoxide that correlates with a conformational change.
    The Journal of biological chemistry, 1999, Aug-20, Volume: 274, Issue:34

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetoxyacetylaminofluorene; Base Sequence; Carcinogens, Environmental; Circular Dichroism; Cytosine; Dinucleoside Phosphates; DNA; DNA Methylation; Humans; Molecular Sequence Data; Nucleic Acid Conformation; Stereoisomerism

1999
Implications of cytosine methylation on (+)-anti-Benzo[a]pyrene 7, 8-dihydrodiol 9,10-epoxide N(2)-dG adduct formation in 5'-d(CGT), 5'-d(CGA), and 5'-d(CGC) sequence contexts of single- and double-stranded oligonucleotides.
    Chemical research in toxicology, 1999, Volume: 12, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Carcinogens; Cytosine; Deoxyguanosine; DNA; DNA Adducts; DNA, Single-Stranded; Methylation; Molecular Sequence Data; Oligonucleotides; Thermodynamics

1999
Conformational changes of a benzo[a]pyrene diol epoxide-N(2)-dG adduct induced by a 5'-flanking 5-methyl-substituted cytosine in a (Me)CG double-stranded oligonucleotide sequence context.
    Chemical research in toxicology, 2002, Volume: 15, Issue:3

    Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; CpG Islands; Cytosine; Deoxyguanosine; DNA Adducts; Electrophoretic Mobility Shift Assay; Fluorescence; Hot Temperature; Methylation; Molecular Conformation; Oligonucleotides; Stereoisomerism

2002
Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms.
    Biochemistry, 2003, Aug-26, Volume: 42, Issue:33

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Aflatoxin B1; Bronchi; Carcinogens; Cells, Cultured; Codon; CpG Islands; Cytosine; DNA; DNA Adducts; DNA Damage; DNA Methylation; Endodeoxyribonucleases; Epithelial Cells; Escherichia coli Proteins; Exons; Fluorenes; Genes, ras; Humans; Mutation

2003
Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Biochemistry, 2004, Dec-21, Volume: 43, Issue:50

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Sequence; Chlorocebus aethiops; Codon; COS Cells; Cytosine; DNA Adducts; DNA Methylation; DNA, Single-Stranded; Genes, p53; Humans; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids

2004
Endogenous cytosine methylation and the formation of carcinogen carcinogen-DNA adducts.
    Nucleic acids symposium series (2004), 2008, Issue:52

    Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Pairing; Carcinogens; CpG Islands; Cytosine; Deoxyguanosine; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Stereoisomerism

2008
The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.
    Journal of mass spectrometry : JMS, 2009, Volume: 44, Issue:8

    Topics: 5-Methylcytosine; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Analytic Sample Preparation Methods; Benzo(a)pyrene; Carcinogens; Chromatography, High Pressure Liquid; Codon; Cytosine; DNA; DNA Adducts; DNA Methylation; Genes, p53; Guanine; Humans; Microchemistry; Mutagens; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2009
Influence of C-5 substituted cytosine and related nucleoside analogs on the formation of benzo[a]pyrene diol epoxide-dG adducts at CG base pairs of DNA.
    Nucleic acids research, 2011, Volume: 39, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Pairing; Chromatography, High Pressure Liquid; Cytosine; Deoxyguanosine; DNA Adducts; Genes, p53; Guanine; Isotope Labeling; Models, Molecular; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Electrochemical study on the effects of epigenetic cytosine methylation on anti-benzo[a]pyrene diol epoxide damage at TP53 oligomers.
    Analytical chemistry, 2013, Jan-15, Volume: 85, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cytosine; DNA Damage; DNA Methylation; Electrochemical Techniques; Electrodes; Epigenesis, Genetic; Genes, p53; Gold; Molecular Structure

2013
Methyl-Cytosine-Driven Structural Changes Enhance Adduction Kinetics of an Exon 7 fragment of the p53 Gene.
    Scientific reports, 2017, 01-19, Volume: 7

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Binding Sites; Chromatography, High Pressure Liquid; Circular Dichroism; CpG Islands; Cytosine; DNA Adducts; Exons; Humans; Kinetics; Molecular Docking Simulation; Nucleic Acid Conformation; Tandem Mass Spectrometry; Tumor Suppressor Protein p53

2017