Compounds > 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and alpha-naphthoflavone

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with alpha-naphthoflavone in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's4 (50.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holder, GM; McManus, ME; Scharping, CE1
Marnett, LJ; Nimesheim, A; Pruess-Schwartz, D1
Dock, L; Jernström, B; Martinez, M; Svensson, SA1
Hines, RN; Novak, RF; Quan, T; Runge-Morris, M; States, JC1
Burchiel, SW; Mounho, BJ1
Burchiel, SW; Lane, J; Lauer, FT; Tannheimer, SL1
Chirnomas, RB; Jeffy, BD; Romagnolo, DF1
Chun, YJ; Chung, JY; Hong, YP; Kim, JM; Kim, JY; Kim, WR; Kim, YJ; Lee, SG; Oh, S; Park, JE; Park, YC; Yoo, KS; Yoo, YH1

Other Studies

8 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and alpha-naphthoflavone

ArticleYear
NADPH-supported and arachidonic acid-supported metabolism of the enantiomers of trans-7,8-dihydrobenzo[a]pyrene-7,8-diol by human liver microsomal samples.
    Carcinogenesis, 1992, Volume: 13, Issue:7

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adolescent; Adult; Aged; Arachidonic Acid; Benzoflavones; Biotransformation; Butylated Hydroxyanisole; Child; Cytochrome P-450 Enzyme System; Humans; Male; Masoprocol; Microsomes, Liver; Middle Aged; NADP; Norpregnenes; Oxidation-Reduction; Progesterone Congeners; Stereoisomerism

1992
Peroxyl radical- and cytochrome P-450-dependent metabolic activation of (+)-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene in mouse skin in vitro and in vivo.
    Cancer research, 1989, Apr-01, Volume: 49, Issue:7

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; DNA Adducts; Epoxy Compounds; Female; In Vitro Techniques; Mice; NADP; Peroxides; Skin

1989
Metabolism of benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide to protein-binding products and glutathione conjugates in isolated rat hepatocytes.
    Carcinogenesis, 1984, Volume: 5, Issue:8

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzoflavones; Benzopyrenes; Chromatography, High Pressure Liquid; Dihydroxydihydrobenzopyrenes; Glutathione; Liver; Macromolecular Substances; Male; Maleates; Proteins; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence

1984
Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Sequence; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cadmium; Cadmium Compounds; Chimera; Cytochrome P-450 Enzyme System; DNA Repair; Enzyme Induction; Fibroblasts; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Isoenzymes; Mice; Molecular Sequence Data; Plasmids; RNA, Messenger; Sulfates; Transfection; Transformation, Genetic; Xeroderma Pigmentosum

1993
Alterations in human B cell calcium homeostasis by polycyclic aromatic hydrocarbons: possible associations with cytochrome P450 metabolism and increased protein tyrosine phosphorylation.
    Toxicology and applied pharmacology, 1998, Volume: 149, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; B-Lymphocytes; Benzo(a)pyrene; Benzoflavones; Benzoquinones; Calcium; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Humans; Lactams, Macrocyclic; Protein-Tyrosine Kinases; Quinones; Rifabutin

1998
Factors influencing elevation of intracellular Ca2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons.
    Molecular carcinogenesis, 1999, Volume: 25, Issue:1

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzoflavones; Benzopyrenes; Breast; Calcium; Carcinogens; Cell Line; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA-Binding Proteins; Egtazic Acid; Epithelial Cells; Humans; Methylcholanthrene; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; RNA, Messenger; Time Factors; Transcription Factors

1999
Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors.
    Environmental and molecular mutagenesis, 2002, Volume: 39, Issue:2-3

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzoflavones; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Carcinogens; DNA Damage; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation.
    Toxicology, 2007, Jun-03, Volume: 235, Issue:1-2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Benzoflavones; Carcinogens; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Down-Regulation; Ellipticines; Enzyme Induction; Enzyme Inhibitors; Liver Neoplasms, Experimental; Mice; Phosphorylation; Receptors, Aryl Hydrocarbon; Tumor Suppressor Protein p53

2007