7,8-dichloro-1,2,3,4-tetrahydroisoquinoline has been researched along with yohimbine in 4 studies
| Studies (7,8-dichloro-1,2,3,4-tetrahydroisoquinoline) | Trials (7,8-dichloro-1,2,3,4-tetrahydroisoquinoline) | Recent Studies (post-2010) (7,8-dichloro-1,2,3,4-tetrahydroisoquinoline) | Studies (yohimbine) | Trials (yohimbine) | Recent Studies (post-2010) (yohimbine) |
|---|---|---|---|---|---|
| 79 | 0 | 0 | 5,893 | 253 | 532 |
| Protein | Taxonomy | 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline (IC50) | yohimbine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.02 | |
| D(2) dopamine receptor | Homo sapiens (human) | 2.06 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0428 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0466 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.126 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.013 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.126 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.074 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.689 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matta, SG; Sharp, BM; Singh, J | 1 |
| Goldberg, MR; Hollister, AS; Robertson, D; Tung, CS | 1 |
| Guchhait, RB; Perry, BD; Stolk, JM; U'Prichard, DC; Vantini, G | 1 |
| Atobe, M; Kariya, T; Kubota, M; Nakagawara, M | 1 |
4 other study(ies) available for 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline and yohimbine
| Article | Year |
|---|---|
Catecholamines mediate nicotine-induced adrenocorticotropin secretion via alpha-adrenergic receptors.
Topics: Adrenocorticotropic Hormone; Animals; Benzylamines; Brain; Brain Stem; Catecholamines; Hydroxydopamines; Isoquinolines; Male; Nicotine; Norepinephrine; Oxidopamine; Prazosin; Rats; Receptors, Adrenergic, alpha; Tetrahydroisoquinolines; Yohimbine | 1990 |
Both alpha- and beta-adrenoreceptors contribute to the central depressor effect of catecholamines.
Topics: Animals; Blood Pressure; Brain; Catecholamines; Heart Rate; Injections, Intraventricular; Isoquinolines; Male; Medulla Oblongata; Nordefrin; Platelet Aggregation; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetrahydroisoquinolines; Timolol; Yohimbine | 1988 |
Assessment of the functional role of brain adrenergic neurons: chronic effects of phenylethanolamine N-methyltransferase inhibitors and alpha adrenergic receptor antagonists on brain norepinephrine metabolism.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Brain; Female; Isoquinolines; Norepinephrine; Phenylethanolamine N-Methyltransferase; Prazosin; Rats; Rats, Inbred F344; Tetrahydroisoquinolines; Tissue Distribution; Tyrosine 3-Monooxygenase; Yohimbine | 1984 |
Effect of phenylethanolamine N-methyltransferase inhibitor, CGS19281A, on the alpha-2-adrenoceptor function in the hypothalamus of rats in comparison with SKF29661, SKF64139 and yohimbine.
Topics: Animals; Carbolines; Clonidine; Hypothalamus; Isoquinolines; Male; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Tetrahydroisoquinolines; Yohimbine | 1996 |